UBXD2

UBXN4
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2KXJ
Identifiers
Aliases	UBXN4 , UBXD2, UBXDC1, erasin, UBX domain protein 4
External IDs	OMIM: 611216; MGI: 1915062; HomoloGene: 40962; GeneCards: UBXN4; OMA:UBXN4 - orthologs
Gene location (Human) Chr. Chromosome 2 (human) [1] Band 2q21.3 Start 135,741,734 bp [1] End 135,785,056 bp [1]
Gene location (Mouse) Chr. Chromosome 1 (mouse) [2] Band 1|1 E3 Start 128,171,701 bp [2] End 128,207,115 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in sperm pylorus cardia secondary oocyte optic nerve seminal vesicula body of pancreas nipple endometrium corpus epididymis Top expressed in lacrimal gland Rostral migratory stream left lobe of liver tail of embryo supraoptic nucleus prostate salivary gland lobe of prostate seminal vesicula retinal pigment epithelium More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding Cellular component nuclear envelope endoplasmic reticulum endoplasmic reticulum membrane nucleus membrane cytosol Biological process response to unfolded protein ubiquitin-dependent ERAD pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 23190 67812 Ensembl ENSG00000144224 ENSMUSG00000026353 UniProt Q92575 Q8VCH8 RefSeq (mRNA) NM_014607 NM_026390 NM_001356529 RefSeq (protein) NP_055422 NP_080666 NP_001343458 Location (UCSC) Chr 2: 135.74 – 135.79 Mb Chr 1: 128.17 – 128.21 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

UBX domain-containing protein 4 is a protein that in humans is encoded by the UBXN4 gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000144224 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000026353 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Liang J, Yin C, Doong H, Fang S, Peterhoff C, Nixon RA, Monteiro MJ (Sep 2006). "Characterization of erasin (UBXD2): a new ER protein that promotes ER-associated protein degradation". J Cell Sci. 119 (Pt 19): 4011–24. doi:10.1242/jcs.03163. PMID   16968747. S2CID   1194226.
6. "Entrez Gene: UBXD2 UBX domain containing 2".

Further reading

• Nagase T, Seki N, Ishikawa K, et al. (1997). "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain". DNA Res. 3 (5): 321–9, 341–54. CiteSeerX   10.1.1.319.3770 . doi: 10.1093/dnares/3.5.321 . PMID   9039502.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC   310948 . PMID   11076863.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC   311072 . PMID   11230166.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Suzuki Y, Yamashita R, Shirota M, et al. (2004). "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions". Genome Res. 14 (9): 1711–8. doi:10.1101/gr.2435604. PMC   515316 . PMID   15342556.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC   528930 . PMID   15489336.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC   1347501 . PMID   16381901.