UBXD2

UBXN4
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2KXJ
Identifiers
Aliases	UBXN4 , UBXD2, UBXDC1, erasin, UBX domain protein 4
External IDs	OMIM: 611216 MGI: 1915062 HomoloGene: 40962 GeneCards: UBXN4
Gene location (Human)
Chr.	Chromosome 2 (human)
End	135,785,056 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	128,207,115 bp
RNA expression pattern
	Top expressed in
	sperm; ; pylorus; ; cardia; ; secondary oocyte; ; optic nerve; ; seminal vesicula; ; body of pancreas; ; nipple; ; endometrium; ; corpus epididymis;
	Top expressed in
	lacrimal gland; ; left lobe of liver; ; supraoptic nucleus; ; prostate; ; salivary gland; ; seminal vesicula; ; retinal pigment epithelium; ; parotid gland; ; motor neuron; ; pituitary gland;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	protein binding ;
Cellular component	nuclear envelope ; endoplasmic reticulum ; endoplasmic reticulum membrane ; nucleus ; membrane ; cytosol ;
Biological process	response to unfolded protein ; ubiquitin-dependent ERAD pathway ;
	Sources:Amigo / QuickGO
Orthologs
	23190
	67812
	ENSG00000144224
	ENSMUSG00000026353
	Q92575
	Q8VCH8
	NM_014607
	NM_026390 ; NM_001356529
	NP_055422
	NP_080666 ; NP_001343458
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated January 14, 2024

UBX domain-containing protein 4 is a protein that in humans is encoded by the UBXN4 gene.^[5]^[6]

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000144224 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000026353 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Liang J, Yin C, Doong H, Fang S, Peterhoff C, Nixon RA, Monteiro MJ (Sep 2006). "Characterization of erasin (UBXD2): a new ER protein that promotes ER-associated protein degradation". J Cell Sci. 119 (Pt 19): 4011–24. doi:10.1242/jcs.03163. PMID 16968747. S2CID 1194226.
↑ "Entrez Gene: UBXD2 UBX domain containing 2".

Nagase T, Seki N, Ishikawa K, et al. (1997). "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain". DNA Res. 3 (5): 321–9, 341–54. CiteSeerX 10.1.1.319.3770 . doi: 10.1093/dnares/3.5.321 . PMID 9039502.
Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948 . PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072 . PMID 11230166.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID 14702039.
Suzuki Y, Yamashita R, Shirota M, et al. (2004). "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions". Genome Res. 14 (9): 1711–8. doi:10.1101/gr.2435604. PMC 515316 . PMID 15342556.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930 . PMID 15489336.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501 . PMID 16381901.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000144224 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000026353 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid16968747-5] Liang J, Yin C, Doong H, Fang S, Peterhoff C, Nixon RA, Monteiro MJ (Sep 2006). "Characterization of erasin (UBXD2): a new ER protein that promotes ER-associated protein degradation". J Cell Sci. 119 (Pt 19): 4011–24. doi:10.1242/jcs.03163. PMID 16968747. S2CID 1194226.

[entrez-6] "Entrez Gene: UBXD2 UBX domain containing 2".

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UBXD2

Related Research Articles

References

Further reading