UFM1 specific peptidase 2 is a protein that in humans is encoded by the UFSP2 gene. [5]
UFM1 specific peptidase 2 is a protein that in humans is encoded by the UFSP2 gene. [5]
This gene encodes a highly conserved cysteine protease. The protein cleaves two C-terminal residues from ubiquitin-fold modifier 1, a ubiquitin-like post-translational modifier protein. Activation of ubiquitin-fold modifier 1 by the encoded protein exposes a C-terminal glycine residue that allows interaction with other proteins and transfer to its target protein. An allelic variant of this gene has been associated with Beukes hip dysplasia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016].
Sentrin-specific protease 6 is an enzyme that in humans is encoded by the SENP6 gene.
Ubiquitin specific peptidase 18 (USP18), also known as UBP43, is an isopeptidase that in human is encoded by the USP18 gene. USP18 is a member of the deubiquitinating protease family of enzymes. It is thought to remove ISG15 adducts from a broad range of protein substrates, a process known as deISGylation. In mice, deletion of this enzyme results in increased inflammatory response to type I interferons, suggesting that USP18 may, in part, regulate interferon responsiveness.
Ubiquitin carboxyl-terminal hydrolase 1 is an enzyme that in humans is encoded by the USP1 gene.
Ubiquitin-like modifier-activating enzyme 5 is a protein that in humans is encoded by the UBA5 gene.
Ubiquitin carboxyl-terminal hydrolase 48 is an enzyme that in humans is encoded by the USP48 gene.
Ubiquitin-specific protease 14 is an enzyme that in humans is encoded by the USP14 gene.
Ubiquitin-fold modifier 1, also known as UFM1, is a protein which in humans is encoded by the UFM1 gene.
Ubiquitin carboxyl-terminal hydrolase 40 is an enzyme that in humans is encoded by the USP40 gene.
Ubiquitin carboxyl-terminal hydrolase 34 is an enzyme that in humans is encoded by the USP34 gene.
CTU2 is a human gene located on chromosome 16. The mRNA encodes the longer isoform. The gene encodes a cytoplasmic protein that plays a probable role in tRNA modification.
Tripartite motif containing 69 is a protein that in humans is encoded by the TRIM69 gene.
Ubiquitin specific peptidase 19 is a protein that in humans is encoded by the USP19 gene.
Ubiquitin specific peptidase 38 is a protein that in humans is encoded by the USP38 gene.
Ubiquitin conjugating enzyme E2 Z (UBE2Z), also known as UBA6-specific E2 enzyme 1 (USE1), is an enzyme that in humans is encoded by the UBE2Z gene on chromosome 17. It is ubiquitously expressed in many tissues and cell types. UBE2Z is an E2 ubiquitin conjugating enzyme and participates in the second step of protein ubiquitination during proteolysis. A genome-wide association study (GWAS) revealed the UBE2Z gene to be associated with chronic kidney disease. The UBE2Z gene also contains one of 27 SNPs associated with increased risk of coronary artery disease.
Ubiquitin specific peptidase 54 is a protein that in humans is encoded by the USP54 gene.
Lon peptidase 2, peroxisomal is a protein that in humans is encoded by the LONP2 gene.
Zinc finger containing ubiquitin peptidase 1 is a protein that in humans is encoded by the ZUP1 gene.
Peptidase inhibitor 15 is a protein that in humans is encoded by the PI15 gene.
Ubiquitin-fold modifier conjugating enzyme 1 is a protein that in humans is encoded by the UFC1 gene.
UFM1 specific peptidase 1 (inactive) is a protein that in humans is encoded by the UFSP1 gene.
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This article incorporates text from the United States National Library of Medicine, which is in the public domain.