UNC84B

SUN2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3UNP, 4DXS, 4DXT, 4FI9
Identifiers
Aliases	SUN2 , UNC84B, Sad1 and UNC84 domain containing 2
External IDs	OMIM: 613569 MGI: 2443011 HomoloGene: 9113 GeneCards: SUN2
Gene location (Human)
Chr.	Chromosome 22 (human)
End	38,794,143 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	79,626,737 bp
RNA expression pattern
	Top expressed in
	gastric mucosa; ; right coronary artery; ; thoracic aorta; ; popliteal artery; ; ascending aorta; ; right lung; ; left coronary artery; ; sural nerve; ; left uterine tube; ; internal globus pallidus;
	Top expressed in
	ascending aorta; ; aortic valve; ; ankle joint; ; lip; ; hair follicle; ; calvaria; ; ankle; ; temporal muscle; ; thymus; ; sternocleidomastoid muscle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	microtubule binding ; protein binding ; identical protein binding ; lamin binding ; protein-membrane adaptor activity ;
Cellular component	integral component of membrane ; endosome ; nuclear membrane ; nuclear envelope ; membrane ; integral component of nuclear inner membrane ; condensed nuclear chromosome ; nuclear inner membrane ; meiotic nuclear membrane microtubule tethering complex ; endosome membrane ; nucleus ;
Biological process	nuclear matrix anchoring at nuclear membrane ; nuclear envelope organization ; nuclear migration along microfilament ; centrosome localization ; positive regulation of cell migration ; mitotic spindle organization ; nuclear migration ; nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration ; meiosis ;
	Sources:Amigo / QuickGO
Orthologs
	25777
	223697
	ENSG00000100242
	ENSMUSG00000042524
	Q9UH99
	Q8BJS4
	NM_001199579 ; NM_001199580 ; NM_015374
	NM_001205345 ; NM_001205346 ; NM_194342
	NP_001186508 ; NP_001186509 ; NP_056189
	NP_001192274 ; NP_001192275 ; NP_919323
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated August 17, 2023

Protein unc-84 homolog B is a protein that in humans is encoded by the UNC84B gene.^[5]^[6]^[7]

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000100242 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000042524 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Raff JW (Feb 2000). "The missing (L) UNC?". Curr Biol. 9 (18): R708–10. doi: 10.1016/S0960-9822(99)80446-1 . PMID 10508607.
↑ Malone CJ, Fixsen WD, Horvitz HR, Han M (Aug 1999). "UNC-84 localizes to the nuclear envelope and is required for nuclear migration and anchoring during C. elegans development". Development. 126 (14): 3171–81. doi:10.1242/dev.126.14.3171. PMID 10375507.
↑ "Entrez Gene: UNC84B unc-84 homolog B (C. elegans)".

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Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Schirmer EC, Florens L, Guan T, et al. (2003). "Nuclear membrane proteins with potential disease links found by subtractive proteomics". Science. 301 (5638): 1380–2. Bibcode:2003Sci...301.1380S. doi:10.1126/science.1088176. PMID 12958361. S2CID 23832536.
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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000100242 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000042524 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10508607-5] Raff JW (Feb 2000). "The missing (L) UNC?". Curr Biol. 9 (18): R708–10. doi: 10.1016/S0960-9822(99)80446-1 . PMID 10508607.

[pmid10375507-6] Malone CJ, Fixsen WD, Horvitz HR, Han M (Aug 1999). "UNC-84 localizes to the nuclear envelope and is required for nuclear migration and anchoring during C. elegans development". Development. 126 (14): 3171–81. doi:10.1242/dev.126.14.3171. PMID 10375507.

[entrez-7] "Entrez Gene: UNC84B unc-84 homolog B (C. elegans)".

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UNC84B

Related Research Articles

References

Further reading