UNKL

For the airport with the ICAO code "UNKL", see Yemelyanovo International Airport.

UNKL
Identifiers
Aliases	UNKL , C16orf28, ZC3H5L, ZC3HDC5L, unkempt family like zinc finger, unk like zinc finger
External IDs	OMIM: 617463 MGI: 1921404 HomoloGene: 62673 GeneCards: UNKL
Gene location (Human) Chr. Chromosome 16 (human) [1] Band 16p13.3 Start 1,363,205 bp [1] End 1,414,751 bp [1]
Gene location (Mouse) Chr. Chromosome 17 (mouse) [2] Band 17|17 A3.3 Start 25,188,397 bp [2] End 25,234,443 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in secondary oocyte sural nerve germinal epithelium right uterine tube Brodmann area 23 parietal pleura visceral pleura Right adrenal gland middle temporal gyrus Left adrenal gland Top expressed in otolith organ utricle trigeminal ganglion cerebellar vermis ciliary body mammillary body supraoptic nucleus medial dorsal nucleus medial geniculate nucleus Paneth cell More reference expression data BioGPS n/a
Gene ontology Molecular function metal ion binding protein binding ubiquitin-protein transferase activity transferase activity DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component nucleus cytoplasm cytosol Biological process protein ubiquitination protein polyubiquitination regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 64718 74154 Ensembl ENSG00000059145 ENSMUSG00000015127 UniProt Q9H9P5 Q5FWH2 RefSeq (mRNA) NM_001037125 NM_001193388 NM_001193389 NM_001276414 NM_001367622 NM_001370526 NM_001372107 NM_024023 NM_001197024 NM_001290736 NM_028789 NM_001357876 NM_001357877 RefSeq (protein) NP_001032202 NP_001180317 NP_001180318 NP_001263343 NP_001354551 NP_001357455 NP_001359036 NP_001183953 NP_001277665 NP_083065 NP_001344805 NP_001344806 Location (UCSC) Chr 16: 1.36 – 1.41 Mb Chr 17: 25.19 – 25.23 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

RING finger protein unkempt-like is a protein that in humans is encoded by the UNKL gene. ^[5]

References

1. GRCh38: Ensembl release 89: ENSG00000059145 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000015127 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: UNKL unkempt homolog (Drosophila)-like".

Further reading

• Mohler J, Weiss N, Murli S, et al. (1992). "The embryonically active gene, unkempt, of Drosophila encodes a Cys3His finger protein". Genetics. 131 (2): 377–88. doi:10.1093/genetics/131.2.377. PMC   1205012 . PMID   1339381.
• Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi: 10.1101/gr.6.9.791 . PMID   8889548.
• Daniels RJ, Peden JF, Lloyd C, et al. (2001). "Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16". Hum. Mol. Genet. 10 (4): 339–52. doi: 10.1093/hmg/10.4.339 . PMID   11157797.
• Venter JC, Adams MD, Myers EW, et al. (2001). "The sequence of the human genome". Science. 291 (5507): 1304–51. Bibcode:2001Sci...291.1304V. doi: 10.1126/science.1058040 . PMID   11181995.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Martin J, Han C, Gordon LA, et al. (2005). "The sequence and analysis of duplication-rich human chromosome 16". Nature. 432 (7020): 988–94. Bibcode:2004Natur.432..988M. doi: 10.1038/nature03187 . PMID   15616553.
• Barrios-Rodiles M, Brown KR, Ozdamar B, et al. (2005). "High-throughput mapping of a dynamic signaling network in mammalian cells". Science. 307 (5715): 1621–5. Bibcode:2005Sci...307.1621B. doi:10.1126/science.1105776. PMID   15761153. S2CID   39457788.
• Oh JH, Yang JO, Hahn Y, et al. (2006). "Transcriptome analysis of human gastric cancer". Mamm. Genome. 16 (12): 942–54. doi:10.1007/s00335-005-0075-2. PMID   16341674. S2CID   69278.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC   1356129 . PMID   16344560.