USP22 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Aliases | USP22 , USP3L, ubiquitin specific peptidase 22 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 612116 MGI: 2144157 HomoloGene: 52664 GeneCards: USP22 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Ubiquitin specific peptidase 22 is a protein that in humans is encoded by the USP22 gene on chromosome 17. [5] USP22 is known to function as a histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. [6]
Histone deacetylase 1 (HDAC1) is an enzyme that in humans is encoded by the HDAC1 gene.
Histone deacetylase 2 (HDAC2) is an enzyme that in humans is encoded by the HDAC2 gene. It belongs to the histone deacetylase class of enzymes responsible for the removal of acetyl groups from lysine residues at the N-terminal region of the core histones. As such, it plays an important role in gene expression by facilitating the formation of transcription repressor complexes and for this reason is often considered an important target for cancer therapy.
Histone deacetylase 6 is an enzyme that in humans is encoded by the HDAC6 gene. HDAC6 has emerged as a highly promising candidate to selectively inhibit as a therapeutic strategy to combat several types of cancer and neurodegenerative disorders.
DNA damage-binding protein 2 is a protein that in humans is encoded by the DDB2 gene.
Histone acetyltransferase KAT5 is an enzyme that in humans is encoded by the KAT5 gene. It is also commonly identified as TIP60.
Protein SET, also known as Protein SET 1, is a protein that in humans is encoded by the SET gene.
Inhibitor of growth protein 1 is a protein that in humans is encoded by the ING1 gene.
Proteasome subunit alpha type-7 also known as 20S proteasome subunit alpha-4 is a protein that in humans is encoded by the PSMA7 gene. This protein is one of the 17 essential subunits that contributes to the complete assembly of 20S proteasome complex.
Histone deacetylase 9 is an enzyme that in humans is encoded by the HDAC9 gene.
Histone H2A type 2-A is a protein that in humans is encoded by the HIST2H2AA3 gene.
Core histone macro-H2A.1 is a protein that in humans is encoded by the H2AFY gene.
Ubiquitin-specific-processing protease 7 (USP7), also known as ubiquitin carboxyl-terminal hydrolase 7 or herpesvirus-associated ubiquitin-specific protease (HAUSP), is an enzyme that in humans is encoded by the USP7 gene.
Sin3A-associated protein, 30kDa, also known as SAP30, is a protein which in humans is encoded by the SAP30 gene.
Mortality factor 4-like protein 1 is a protein that in humans is encoded by the MORF4L1 gene.
Metastasis-associated protein MTA2 is a protein that in humans is encoded by the MTA2 gene.
Inhibitor of growth protein 2 is a protein that in humans is encoded by the ING2 gene.
Ubiquitin specific peptidase 10, also known as USP10, is an enzyme which in humans is encoded by the USP10 gene.
K(lysine) acetyltransferase 8 (KAT8) is an enzyme that in humans is encoded by the KAT8 gene.
JADE1 is a protein that in humans is encoded by the JADE1 gene.
Ubiquitin-specific protease 14 is an enzyme that in humans is encoded by the USP14 gene.