USP42

USP42
Identifiers
Aliases	USP42 , ubiquitin specific peptidase 42
External IDs	MGI: 1924050; HomoloGene: 35425; GeneCards: USP42; OMA:USP42 - orthologs
Gene location (Human) Chr. Chromosome 7 (human) [1] Band 7p22.1 Start 6,104,949 bp [1] End 6,161,564 bp [1]
Gene location (Mouse) Chr. Chromosome 5 (mouse) [2] Band 5 G2|5 82.5 cM Start 143,696,080 bp [2] End 143,718,035 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in sperm pancreatic epithelial cell mucosa of ileum pancreatic ductal cell testicle Brodmann area 23 tibialis anterior muscle nipple cartilage tissue postcentral gyrus Top expressed in cumulus cell vas deferens utricle tail of embryo seminiferous tubule abdominal wall maxillary prominence genital tubercle mandibular prominence foot More reference expression data BioGPS n/a
Gene ontology Molecular function cysteine-type peptidase activity protein binding peptidase activity hydrolase activity thiol-dependent deubiquitinase cysteine-type endopeptidase activity Cellular component nucleoplasm Biological process ubiquitin-dependent protein catabolic process spermatogenesis proteolysis cell differentiation protein deubiquitination regulation of apoptotic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 84132 76800 Ensembl ENSG00000106346 ENSMUSG00000051306 UniProt Q9H9J4 B2RQC2 RefSeq (mRNA) NM_032172 NM_001365764 NM_001389650 NM_029749 RefSeq (protein) NP_115548 NP_001352693 NP_084025 Location (UCSC) Chr 7: 6.1 – 6.16 Mb Chr 5: 143.7 – 143.72 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Ubiquitin carboxyl-terminal hydrolase 42 is an enzyme that in humans is encoded by the USP42 gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000106346 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000051306 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Puente XS, Sanchez LM, Overall CM, Lopez-Otin C (Jul 2003). "Human and mouse proteases: a comparative genomic approach". Nat Rev Genet. 4 (7): 544–58. doi:10.1038/nrg1111. PMID   12838346. S2CID   2856065.
6. "Entrez Gene: USP42 ubiquitin specific peptidase 42".

Further reading

• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi: 10.1016/j.cell.2006.09.026 . PMID   17081983. S2CID   7827573.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi: 10.1073/pnas.0404720101 . PMC   514446 . PMID   15302935.
• Quesada V, Díaz-Perales A, Gutiérrez-Fernández A, et al. (2004). "Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases". Biochem. Biophys. Res. Commun. 314 (1): 54–62. doi:10.1016/j.bbrc.2003.12.050. PMID   14715245.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi: 10.1101/gr.6.9.791 . PMID   8889548.