USP51

USP51
Identifiers
Aliases	USP51 , ubiquitin specific peptidase 51
External IDs	MGI: 3588217 HomoloGene: 71495 GeneCards: USP51
Gene location (Human) Chr. X chromosome (human) [1] Band Xp11.21 Start 55,484,616 bp [1] End 55,489,848 bp [1]
Gene location (Mouse) Chr. X chromosome (mouse) [2] Band X|X F3 Start 151,789,465 bp [2] End 151,792,412 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in corpus epididymis caput epididymis bronchial epithelial cell retinal pigment epithelium endothelial cell germinal epithelium islet of Langerhans Stromal cell of endometrium parietal pleura smooth muscle tissue Top expressed in yolk sac secondary oocyte morula placenta mesencephalon mirror islet of Langerhans adrenal gland neural tube hypothalamus More reference expression data BioGPS n/a
Gene ontology Molecular function thiol-dependent deubiquitinase zinc ion binding peptidase activity cysteine-type peptidase activity hydrolase activity metal ion binding chromatin binding histone binding Cellular component chromosome Biological process protein deubiquitination ubiquitin-dependent protein catabolic process proteolysis histone deubiquitination regulation of response to DNA damage stimulus regulation of cell cycle process regulation of double-strand break repair via homologous recombination regulation of double-strand break repair via nonhomologous end joining DNA repair cellular response to DNA damage stimulus Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 158880 635253 Ensembl ENSG00000247746 ENSMUSG00000067215 UniProt Q70EK9 B1AY15 RefSeq (mRNA) NM_201286 NM_001137547 RefSeq (protein) NP_958443 NP_001131019 Location (UCSC) Chr X: 55.48 – 55.49 Mb Chr X: 151.79 – 151.79 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Ubiquitin carboxyl-terminal hydrolase 51 is an enzyme that in humans is encoded by the USP51 gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000247746 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000067215 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Puente XS, Sanchez LM, Overall CM, Lopez-Otin C (Jul 2003). "Human and mouse proteases: a comparative genomic approach". Nat Rev Genet. 4 (7): 544–58. doi:10.1038/nrg1111. PMID   12838346. S2CID   2856065.
6. "Entrez Gene: USP51 ubiquitin specific peptidase 51".

Further reading

• Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome". Nature. 434 (7031): 325–37. Bibcode:2005Natur.434..325R. doi:10.1038/nature03440. PMC   2665286 . PMID   15772651.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Puente XS, López-Otín C (2004). "A genomic analysis of rat proteases and protease inhibitors". Genome Res. 14 (4): 609–22. doi:10.1101/gr.1946304. PMC   383305 . PMID   15060002.
• Xie H, Diber A, Pollock S, et al. (2004). "Bridging expressed sequence alignments through targeted cDNA sequencing". Genomics. 83 (4): 572–6. doi:10.1016/j.ygeno.2003.07.003. PMID   15028280.
• Quesada V, Díaz-Perales A, Gutiérrez-Fernández A, et al. (2004). "Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases". Biochem. Biophys. Res. Commun. 314 (1): 54–62. doi:10.1016/j.bbrc.2003.12.050. PMID   14715245.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Dias Neto E, Correa RG, Verjovski-Almeida S, et al. (2000). "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags". Proc. Natl. Acad. Sci. U.S.A. 97 (7): 3491–6. Bibcode:2000PNAS...97.3491D. doi: 10.1073/pnas.97.7.3491 . PMC   16267 . PMID   10737800.