UTP6

UTP6
Identifiers
Aliases	UTP6 , C17orf40, HCA66, small subunit processome component, UTP6 small subunit processome component
External IDs	MGI: 2445193; HomoloGene: 41265; GeneCards: UTP6; OMA:UTP6 - orthologs
Gene location (Human) Chr. Chromosome 17 (human) [1] Band 17q11.2 Start 31,860,904 bp [1] End 31,901,708 bp [1]
Gene location (Mouse) Chr. Chromosome 11 (mouse) [2] Band 11 B5|11 47.29 cM Start 79,823,147 bp [2] End 79,853,216 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Achilles tendon cerebellar hemisphere ventricular zone granulocyte monocyte right hemisphere of cerebellum ganglionic eminence anterior pituitary tibial nerve right testis Top expressed in epiblast otic placode otic vesicle ventricular zone abdominal wall mandibular prominence maxillary prominence Epithelium of choroid plexus neural layer of retina primitive streak More reference expression data BioGPS More reference expression data
Gene ontology Molecular function snoRNA binding Cellular component small-subunit processome Pwp2p-containing subcomplex of 90S preribosome nucleolus nucleus nucleoplasm Biological process RNA processing maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) rRNA processing Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55813 216987 Ensembl ENSG00000108651 ENSMUSG00000035575 UniProt Q9NYH9 Q8VCY6 RefSeq (mRNA) NM_018428 NM_144826 RefSeq (protein) NP_060898 NP_659075 Location (UCSC) Chr 17: 31.86 – 31.9 Mb Chr 11: 79.82 – 79.85 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

U3 small nucleolar RNA-associated protein 6 homolog is a protein that in humans is encoded by the UTP6 gene. ^{[5] [6] [7]}

See also

• Fibrillarin
• Small nucleolar RNA U3
• RCL1
• RRP9
• UTP11L
• UTP14A
• UTP15

References

1. GRCh38: Ensembl release 89: ENSG00000108651 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000035575 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Jenne DE, Tinschert S, Stegmann E, Reimann H, Nurnberg P, Horn D, Naumann I, Buske A, Thiel G (Jul 2000). "A common set of at least 11 functional genes is lost in the majority of NF1 patients with gross deletions". Genomics. 66 (1): 93–7. doi:10.1006/geno.2000.6179. PMID   10843809.
6. Venturin M, Bentivegna A, Moroni R, Larizza L, Riva P (Sep 2005). "Evidence by expression analysis of candidate genes for congenital heart defects in the NF1 microdeletion interval". Ann Hum Genet. 69 (Pt 5): 508–16. doi:10.1111/j.1529-8817.2005.00203.x. PMID   16138909. S2CID   45891228.
7. "Entrez Gene: UTP6 UTP6, small subunit (SSU) processome component, homolog (yeast)".

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID   8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID   9373149.
• Wang Y, Han KJ, Pang XW, et al. (2002). "Large scale identification of human hepatocellular carcinoma-associated antigens by autoantibodies". J. Immunol. 169 (2): 1102–9. doi: 10.4049/jimmunol.169.2.1102 . PMID   12097419.
• Scherl A, Couté Y, Déon C, et al. (2003). "Functional proteomic analysis of human nucleolus". Mol. Biol. Cell. 13 (11): 4100–9. doi:10.1091/mbc.E02-05-0271. PMC   133617 . PMID   12429849.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. Bibcode:2005Natur.433...77A. doi:10.1038/nature03207. PMID   15635413. S2CID   4344740.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID   16189514. S2CID   4427026.
• Piddubnyak V, Rigou P, Michel L, et al. (2007). "Positive regulation of apoptosis by HCA66, a new Apaf-1 interacting protein, and its putative role in the physiopathology of NF1 microdeletion syndrome patients". Cell Death Differ. 14 (6): 1222–33. doi: 10.1038/sj.cdd.4402122 . PMID   17380155.
• Douglas J, Cilliers D, Coleman K, et al. (2007). "Mutations in RNF135, a gene within the NF1 microdeletion region, cause phenotypic abnormalities including overgrowth". Nat. Genet. 39 (8): 963–5. doi:10.1038/ng2083. PMID   17632510. S2CID   35797973.