VMP1

VMP1
Identifiers
Aliases	VMP1 , EPG3, TANGO5, TMEM49, vacuole membrane protein 1
External IDs	OMIM: 611753; MGI: 1923159; HomoloGene: 23686; GeneCards: VMP1; OMA:VMP1 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	59,842,255 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	86,574,662 bp
RNA expression pattern
	Top expressed in
	blood; ; monocyte; ; gallbladder; ; rectum; ; mucosa of urinary bladder; ; islet of Langerhans; ; pericardium; ; upper lobe of left lung; ; appendix; ; spleen;
	Top expressed in
	jejunum; ; yolk sac; ; ileum; ; duodenum; ; lacrimal gland; ; seminal vesicula; ; parotid gland; ; globus pallidus; ; Region I of hippocampus proper; ; conjunctival fornix;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding ;
Cellular component	vacuolar membrane ; integral component of membrane ; vacuole ; plasma membrane ; autophagosome membrane ; nucleolus ; endoplasmic reticulum ; membrane ; phagophore assembly site ; endoplasmic reticulum-Golgi intermediate compartment membrane ;
Biological process	autophagy ; cell adhesion ; Golgi organization ; embryo implantation ; endoplasmic reticulum organization ; exocytosis ; cell junction assembly ; cell-cell adhesion ; autophagosome assembly ;
	Sources:Amigo / QuickGO
Orthologs
	81671
	75909
	ENSG00000062716
	ENSMUSG00000018171
	Q96GC9
	Q99KU0
NM_001329394 ; NM_001329395 ; NM_001329396 ; NM_001329397 ; NM_001329398 ;
	NM_001329399 ; NM_001329400 ; NM_001329401 ; NM_001329402 ; NM_030938
	NM_029478 ; NM_001356531 ; NM_001379040 ; NM_001379041
NP_001316323 ; NP_001316324 ; NP_001316325 ; NP_001316326 ; NP_001316327 ;
	NP_001316328 ; NP_001316329 ; NP_001316330 ; NP_001316331 ; NP_112200
	NP_083754 ; NP_001343460 ; NP_001365969 ; NP_001365970
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated May 26, 2024

Vacuole membrane protein 1 is a protein that in humans is encoded by the VMP1 gene.^[5]^[6]^[7]

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000062716 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000018171 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072 . PMID 11230166.
↑ Dusetti NJ, Jiang Y, Vaccaro MI, Tomasini R, Azizi Samir A, Calvo EL, Ropolo A, Fiedler F, Mallo GV, Dagorn JC, Iovanna JL (Jan 2002). "Cloning and expression of the rat vacuole membrane protein 1 (VMP1), a new gene activated in pancreas with acute pancreatitis, which promotes vacuole formation". Biochem Biophys Res Commun. 290 (2): 641–9. doi:10.1006/bbrc.2001.6244. PMID 11785947.
↑ "VMP1 vacuole membrane protein 1 [ Homo sapiens (human) ]".

Ropolo A, Grasso D, Pardo R, et al. (2008). "The pancreatitis-induced vacuole membrane protein 1 triggers autophagy in mammalian cells". J. Biol. Chem. 282 (51): 37124–33. doi: 10.1074/jbc.M706956200 . PMID 17940279.
Sauermann M, Sahin O, Sültmann H, et al. (2008). "Reduced expression of vacuole membrane protein 1 affects the invasion capacity of tumor cells". Oncogene. 27 (9): 1320–6. doi:10.1038/sj.onc.1210743. PMID 17724469. S2CID 1805602.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501 . PMID 16381901.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930 . PMID 15489336.
Starkuviene V, Liebel U, Simpson JC, et al. (2004). "High-content screening microscopy identifies novel proteins with a putative role in secretory membrane traffic". Genome Res. 14 (10A): 1948–56. doi:10.1101/gr.2658304. PMC 524419 . PMID 15466293.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732 . PMID 11256614.
Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948 . PMID 11076863.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000062716 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000018171 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11230166-5] Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072 . PMID 11230166.

[pmid11785947-6] Dusetti NJ, Jiang Y, Vaccaro MI, Tomasini R, Azizi Samir A, Calvo EL, Ropolo A, Fiedler F, Mallo GV, Dagorn JC, Iovanna JL (Jan 2002). "Cloning and expression of the rat vacuole membrane protein 1 (VMP1), a new gene activated in pancreas with acute pancreatitis, which promotes vacuole formation". Biochem Biophys Res Commun. 290 (2): 641–9. doi:10.1006/bbrc.2001.6244. PMID 11785947.

[entrez-7] "VMP1 vacuole membrane protein 1 [ Homo sapiens (human) ]".

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VMP1

Related Research Articles

References

Further reading