VPS26B

VPS26B
Identifiers
Aliases	VPS26B , Pep8b, VPS26 retromer complex component B, VPS26, retromer complex component B
External IDs	OMIM: 610027; MGI: 1917656; HomoloGene: 3601; GeneCards: VPS26B; OMA:VPS26B - orthologs
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11q25 Start 134,224,671 bp [1] End 134,247,788 bp [1]
Gene location (Mouse) Chr. Chromosome 9 (mouse) [2] Band 9|9 A4 Start 26,919,067 bp [2] End 26,941,361 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right hemisphere of cerebellum skin of arm ganglionic eminence granulocyte right frontal lobe prefrontal cortex skin of leg Brodmann area 9 skin of abdomen cingulate gyrus Top expressed in ascending aorta aortic valve granulocyte Region I of hippocampus proper subiculum nucleus accumbens supraoptic nucleus cerebellar cortex barrel cortex olfactory tubercle More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding Cellular component cytoplasm retromer complex late endosome early endosome membrane retromer, cargo-selective complex endosome cytosol phagocytic vesicle Biological process protein transport retrograde transport, endosome to Golgi regulation of macroautophagy intracellular protein transport cellular response to interferon-gamma signal transduction Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 112936 69091 Ensembl ENSG00000151502 ENSMUSG00000031988 UniProt Q4G0F5 Q8C0E2 RefSeq (mRNA) NM_052875 NM_178027 RefSeq (protein) NP_443107 NP_443107.1 NP_821170 Location (UCSC) Chr 11: 134.22 – 134.25 Mb Chr 9: 26.92 – 26.94 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Vacuolar protein sorting 26 homolog B (S. pombe) is a protein in humans that is encoded by the VPS26B gene. ^[5]

References

1. GRCh38: Ensembl release 89: ENSG00000151502 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000031988 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: Vacuolar protein sorting 26 homolog B (S. pombe)".

Further reading

• Haft CR, de la Luz Sierra M, Bafford R, Lesniak MA, Barr VA, Taylor SI (December 2000). "Human orthologs of yeast vacuolar protein sorting proteins Vps26, 29, and 35: assembly into multimeric complexes". Mol. Biol. Cell. 11 (12): 4105–16. doi:10.1091/mbc.11.12.4105. PMC   15060 . PMID   11102511.
• Kerr MC, Bennetts JS, Simpson F, Thomas EC, Flegg C, Gleeson PA, Wicking C, Teasdale RD (November 2005). "A novel mammalian retromer component, Vps26B". Traffic. 6 (11): 991–1001. doi:10.1111/j.1600-0854.2005.00328.x. PMID   16190980. S2CID   31954489.