VPS72

VPS72
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 5FUG
Identifiers
Aliases	VPS72 , CFL1, Swc2, TCFL1, YL-1, YL1, vacuolar protein sorting 72 homolog
External IDs	OMIM: 600607; MGI: 1202305; HomoloGene: 110905; GeneCards: VPS72; OMA:VPS72 - orthologs
Gene location (Human) Chr. Chromosome 1 (human) [1] Band 1q21.3 Start 151,176,304 bp [1] End 151,195,321 bp [1]
Gene location (Mouse) Chr. Chromosome 3 (mouse) [2] Band 3|3 F2.1 Start 95,018,333 bp [2] End 95,030,362 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in secondary oocyte ganglionic eminence ventricular zone Achilles tendon gastrocnemius muscle islet of Langerhans muscle of thigh smooth muscle tissue stromal cell of endometrium prefrontal cortex Top expressed in ventricular zone muscle of thigh medial ganglionic eminence neural tube zygote lip internal carotid artery external carotid artery neural layer of retina embryo More reference expression data BioGPS More reference expression data
Gene ontology Molecular function DNA binding protein binding histone binding Cellular component nucleus nucleoplasm nuclear speck protein-containing complex Biological process chromatin remodeling regulation of transcription, DNA-templated negative regulation of transcription by RNA polymerase II somatic stem cell population maintenance transcription, DNA-templated histone exchange chromatin organization Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 6944 21427 Ensembl ENSG00000163159 ENSMUSG00000008958 UniProt Q15906 Q62481 RefSeq (mRNA) NM_005997 NM_001271087 NM_001271088 NM_009336 RefSeq (protein) NP_001258016 NP_001258017 NP_005988 NP_033362 Location (UCSC) Chr 1: 151.18 – 151.2 Mb Chr 3: 95.02 – 95.03 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Vacuolar protein sorting-associated protein 72 homolog is a protein that in humans is encoded by the VPS72 gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000163159 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000008958 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Horikawa I, Tanaka H, Yuasa Y, Suzuki M, Oshimura M (Mar 1995). "Molecular cloning of a novel human cDNA on chromosome 1q21 and its mouse homolog encoding a nuclear protein with DNA-binding ability". Biochemical and Biophysical Research Communications. 208 (3): 999–1007. doi:10.1006/bbrc.1995.1433. PMID   7702631.
6. "Entrez Gene: VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae)".

Further reading

• Maruyama K, Sugano S (Jan 1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID   8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (Oct 1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID   9373149.
• Cai Y, Jin J, Florens L, Swanson SK, Kusch T, Li B, Workman JL, Washburn MP, Conaway RC, Conaway JW (Apr 2005). "The mammalian YL1 protein is a shared subunit of the TRRAP/TIP60 histone acetyltransferase and SRCAP complexes". The Journal of Biological Chemistry. 280 (14): 13665–70. doi: 10.1074/jbc.M500001200 . PMID   15647280.
• Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID   16189514. S2CID   4427026.
• Denoeud F, Kapranov P, Ucla C, Frankish A, Castelo R, Drenkow J, Lagarde J, Alioto T, Manzano C, Chrast J, Dike S, Wyss C, Henrichsen CN, Holroyd N, Dickson MC, Taylor R, Hance Z, Foissac S, Myers RM, Rogers J, Hubbard T, Harrow J, Guigó R, Gingeras TR, Antonarakis SE, Reymond A (Jun 2007). "Prominent use of distal 5' transcription start sites and discovery of a large number of additional exons in ENCODE regions". Genome Research. 17 (6): 746–59. doi:10.1101/gr.5660607. PMC   1891335 . PMID   17567994.