VTI1A

Last updated
VTI1A
PDB 2nps EBI.png
Identifiers
Aliases VTI1A , MMDS3, MVti1, VTI1RP2, Vti1-rp2, vesicle transport through interaction with t-SNAREs 1A
External IDs OMIM: 614316 MGI: 1855699 HomoloGene: 39963 GeneCards: VTI1A
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001293685
NM_001293686
NM_016862
NM_001360431
NM_001360432

RefSeq (protein)

NP_001280614
NP_001280615
NP_058558
NP_001347360
NP_001347361

Location (UCSC) Chr 10: 112.45 – 112.82 Mb Chr 19: 55.3 – 55.62 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Vesicle transport through interaction with t-SNAREs homolog 1A is a protein that in humans is encoded by the VTI1A gene. [5] [6]

The protein encoded by the VTI1A gene is a vesicular-SNARE (v-SNARE) protein which is located in the membranes of target vesicle compartments. [7]

Related Research Articles

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Syntaxin-8 is a protein that in humans is encoded by the STX8 gene. Syntaxin 8 directly interacts with HECTd3 and has similar subcellular localization. The protein has been shown to form the SNARE complex with syntaxin 7, vti1b and endobrevin. These function as the machinery for the homotypic fusion of late endosomes.

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References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000151532 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000024983 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: vesicle transport through interaction with t-SNAREs homolog 1A (yeast)".
  6. Fischer von Mollard G, Stevens TH (January 1998). "A human homolog can functionally replace the yeast vesicle-associated SNARE Vti1p in two vesicle transport pathways". J. Biol. Chem. 273 (5): 2624–30. doi: 10.1074/jbc.273.5.2624 . PMID   9446565.
  7. "VTI1A vesicle transport through interaction with t-SNAREs 1A [Homo sapiens (Human)] - Gene - NCBI".

Further reading