Variecolactone

Last updated
Variecolactone.svg
Names
IUPAC name
(1S,3R,6S,9S,10S,11S,13E,17R,19S,20R)-17-hydroxy-3,6,19-trimethyl-9-prop-1-en-2-yl-16-oxapentacyclo[12.5.1.03,11.06,10.017,20]icos-13-en-15-one
Preferred IUPAC name
[1S,2aR,2a1R,4a(5)E,6aS,6bS,7S,9aS,11aR,12aS]-2a-Hydroxy-1,9a,11a-trimethyl-7-(prop-1-en-2-yl)-1,2,2a,2a1,6,6a,6b,7,8,9,9a,10,11,11a,12,12a-hexadecahydro-4H-3-oxapentaleno[1′,6′:4,5,6]cycloocta[1,2-a]inden-4-one
Identifiers
  • 216445-01-1 X mark.svgN
3D model (JSmol)
PubChem CID
  • InChI=1S/C25H36O3/c1-14(2)16-8-9-23(4)10-11-24(5)13-18-15(3)12-25(27)20(18)17(22(26)28-25)6-7-19(24)21(16)23/h6,15-16,18-21,27H,1,7-13H2,2-5H3/b17-6+/t15-,16+,18-,19-,20-,21-,23-,24+,25+/m0/s1
    Key: FHJWMBGJDFBYNQ-SSPKKXFYSA-N
  • C[C@H]1C[C@@]2([C@@H]/3[C@H]1C[C@]4(CC[C@@]5(CC[C@@H]([C@H]5[C@@H]4C/C=C3/C(=O)O2)C(=C)C)C)C)O
Properties
C25H36O3
Molar mass 384.560 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Variecolactone is a bio-active ascomycete isolate. [1]

Related Research Articles

Ascomycota Division or phylum of fungi

Ascomycota is a phylum of the kingdom Fungi that, together with the Basidiomycota, forms the subkingdom Dikarya. Its members are commonly known as the sac fungi or ascomycetes. It is the largest phylum of Fungi, with over 64,000 species. The defining feature of this fungal group is the "ascus", a microscopic sexual structure in which nonmotile spores, called ascospores, are formed. However, some species of the Ascomycota are asexual, meaning that they do not have a sexual cycle and thus do not form asci or ascospores. Familiar examples of sac fungi include morels, truffles, brewer's yeast and baker's yeast, dead man's fingers, and cup fungi. The fungal symbionts in the majority of lichens such as Cladonia belong to the Ascomycota.

The hymenium is the tissue layer on the hymenophore of a fungal fruiting body where the cells develop into basidia or asci, which produce spores. In some species all of the cells of the hymenium develop into basidia or asci, while in others some cells develop into sterile cells called cystidia (basidiomycetes) or paraphyses (ascomycetes). Cystidia are often important for microscopic identification. The subhymenium consists of the supportive hyphae from which the cells of the hymenium grow, beneath which is the hymenophoral trama, the hyphae that make up the mass of the hymenophore.

Sordariomycetes Class of fungi

Sordariomycetes is a class of fungi in the subdivision Pezizomycotina (Ascomycota), consisting of 28 orders, 90 families, 1344 genera. Sordariomycetes is from the Latin sordes (filth) because some species grow in animal feces, though growth habits vary widely across the class.

Operculum (botany)


In botany, an operculum or calyptra is a cap-like structure in some flowering plants, mosses, and fungi. It is a covering, hood or lid, describing a feature in plant morphology.

Saccharomycetes Class of fungi

Saccharomycetes belongs to the kingdom of Fungi and the division Ascomycota. It is the only class in the subdivision Saccharomycotina, the budding yeasts. Saccharomycetes contains a single order: Saccharomycetales.

Čeláre

Čeláre is a village and municipality in the Veľký Krtíš District of the Banská Bystrica Region of southern Slovakia.

Mating types are the microorganism equivalent to gender in higher organisms and is thought to be the ancestor to sexes.

Hont, Hungary

Hont is a village in Nógrád County in Hungary.

Onygenales Order of fungi

The Onygenales are an order of Ascomycetes, within the eurotiomycetes Ascomycetes.

<i>Verpa</i> Genus of fungi

Verpa is a genus of ascomycete fungi related to the morels. Resembling the latter genus in edibility and form, the common name early morels is popular. There are five species in the widespread genus.

Morchellaceae Family of fungi

The Morchellaceae are a family of ascomycete fungi in the order Pezizales. According to a standard reference work, the family has contained at least 49 species distributed among four genera. However, in 2012, five genera that produce ascoma that are sequestrate and hypogeous were added. The best-known members are the highly regarded and commercially picked true morels of the genus Morchella, the thimble morels of the genus Verpa, and a genus of cup-shaped fungi Disciotis. The remaining four genera produce the sequestrate fruit bodies.

Laurel Mill, also known as just Laurel, is an unincorporated community in northeastern Franklin County, North Carolina, United States. It is located west of Centerville, at an elevation of 292 feet. The primary cross roads where the community is located are Laurel Mill-Centerville Road, Jones Chapel Road and Laurel Mill Road.

Helvellaceae Family of fungi

The Helvellaceae are a family of ascomycete fungi, the best-known members of which are the elfin saddles of the genus Helvella. Originally erected by Elias Magnus Fries in 1823 as Elvellacei, it contained many genera. Several of these, such as Gyromitra and Discina, have been found to be more distantly related in a molecular study of ribosomal DNA by mycologist Kerry O'Donnell in 1997, leaving a much smaller core clade now redefined as Helvellaceae. Instead, this narrowly defined group is most closely related to the true truffles of the Tuberaceae. Although the Dictionary of the Fungi considered the Helvellaceae to contain six genera and 63 species, genetic analysis has shown that Leucangium, previously classified in this family, is more closely related to the Morchellaceae.

Homothallic refers to the possession, within a single organism, of the resources to reproduce sexually; i.e., having male and female reproductive structures on the same thallus. The opposite sexual functions are performed by different cells of a single mycelium.

Clark Thomas Rogerson American mycologist (1918–2001)

Clark Thomas Rogerson,, was an American mycologist. He was known for his work in the Hypocreales (Ascomycota), particularly Hypomyces, a genus of fungi that parasitize other fungi. After receiving his doctorate from Cornell University in 1950, he went on to join the faculty of Kansas State University. In 1958, he became a curator at The New York Botanical Garden, and served as editor for various academic journals published by the Garden. Rogerson was involved with the Mycological Society of America, serving in various positions, including President in 1969. He was Managing Editor (1958–89) and Editor-in-chief (1960–65) of the scientific journal Mycologia.

Variecolol Chemical compound

Variecolol is an immunosuppressant/antiviral compound isolated from ascomycete.

Siege of Paris (1429)

The siege of Paris was an assault undertaken in September 1429 during the Hundred Years' War by the troops of the recently crowned King Charles VII of France, with the notable presence of Joan of Arc, to take the city held by the English and the Burgundians. King Charles's French troops failed to enter Paris, defended by the governor Jean de Villiers de L'Isle-Adam and the provost Simon Morhier, with the support of much of the city's population.

NGC 1436 Barred spiral galaxy in the constellation Eridanus

NGC 1436 is a barred spiral galaxy approximately 58 million light-years away from Earth in the constellation of Eridanus. It is a member of the Fornax I cluster.

Marie-Agnès Letrouit-Galinou is a French botanist, mycologist, and lichenologist, known for her contribution to revolutionizing the scientific understanding of ascomycete development and classification.

Saccharomyceta

Saccharomyceta is a clade of fungi containing Pezizomycotina and Saccharomycotina, or all Ascomycete fungi except Taphrinomycotina according to the 2007 fungal phylogeny "The Mycota: A Comprehensive Treatise on Fungi as Experimental Systems for Basic and Applied Research" and Tedersoo et al. 2018.

References

  1. Fujimoto, Haruhiro; Nakamura, Etsuko; Okuyama, Emi; Ishibashi, Masami (2000). "Immunomodulatory Constituents from an Ascomycete, Emericella aurantio-brunnea". Chemical and Pharmaceutical Bulletin. 48 (10): 1436–1441. doi:10.1248/cpb.48.1436. PMID   11045446.