Villin 1 is a protein that in humans is encoded by the VIL1 gene. [5]
This gene encodes a member of a family of calcium-regulated actin-binding proteins. This protein represents a dominant part of the brush border cytoskeleton which functions in the capping, severing, and bundling of actin filaments. Two mRNAs of 2.7 kb and 3.5 kb have been observed; they result from utilization of alternate poly-adenylation signals present in the terminal exon. [provided by RefSeq, Jul 2008].
Cofilin 1 , also known as CFL1, is a human gene, part of the ADF/cofilin family.
Cortactin is a monomeric protein located in the cytoplasm of cells that can be activated by external stimuli to promote polymerization and rearrangement of the actin cytoskeleton, especially the actin cortex around the cellular periphery. It is present in all cell types. When activated, it will recruit Arp2/3 complex proteins to existing actin microfilaments, facilitating and stabilizing nucleation sites for actin branching. Cortactin is important in promoting lamellipodia formation, invadopodia formation, cell migration, and endocytosis.
Ezrin also known as cytovillin or villin-2 is a protein that in humans is encoded by the EZR gene.
Filamin A, alpha (FLNA) is a protein that in humans is encoded by the FLNA gene.
LIM domain kinase 1 is an enzyme that in humans is encoded by the LIMK1 gene.
Dynamin-2 is a protein that in humans is encoded by the DNM2 gene.
Alpha-actinin-1 is a protein that in humans is encoded by the ACTN1 gene.
Vasodilator-stimulated phosphoprotein is a protein that in humans is encoded by the VASP gene.
Ras GTPase-activating-like protein IQGAP1 (IQGAP1) also known as p195 is a ubiquitously expressed protein that in humans is encoded by the IQGAP1 gene. IQGAP1 is a scaffold protein involved in regulating various cellular processes ranging from organization of the actin cytoskeleton, transcription, and cellular adhesion to regulating the cell cycle.
RhoC is a small signaling G protein, and is a member of the Rac subfamily of the family Rho family of GTPases. It is encoded by the gene RHOC.
Zyxin is a protein that in humans is encoded by the ZYX gene.
Proto-oncogene tyrosine-protein kinase FER is an enzyme that in humans is encoded by the FER gene.
CD2-associated protein is a protein that in humans is encoded by the CD2AP gene.
Chloride intracellular channel 4, also known as CLIC4,p644H1,HuH1, is a eukaryotic gene.
Profilin-2 is a protein that in humans is encoded by the PFN2 gene.
Ena/VASP-like protein is a member of the Ena/VASP family of proteins that in humans is encoded by the EVL gene.
Vinexin is a protein that in humans is encoded by the SORBS3 gene.
Neurabin-2 is a protein that in humans is encoded by the PPP1R9B gene.
Macrophage-capping protein (CAPG) also known as actin regulatory protein CAP-G is a protein that in humans is encoded by the CAPG gene.
Filamin-binding LIM protein 1 is a protein that in humans is encoded by the FBLIM1 gene.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.