WD repeat-containing protein 1 is a protein that in humans is encoded by the WDR1 gene. [5] [6]
This gene encodes a protein containing 9 WD repeats. WD repeats are approximately 30- to 40-amino acid domains containing several conserved residues, mostly including a trp-asp at the C-terminal end. WD domains are involved in protein-protein interactions. The encoded protein may help induce the disassembly of actin filaments. Two transcript variants encoding different isoforms have been found for this gene. [6]
Drebrin is a protein that in humans is encoded by the DBN1 gene.
LIM domain and actin-binding protein 1 is a protein that in humans is encoded by the LIMA1 gene.
WD repeat-containing protein 33 is a protein that in humans is encoded by the WDR33 gene.
60S ribosomal protein L18a is a protein that in humans is encoded by the RPL18A gene.
WD repeat-containing protein 5 is a protein that in humans is encoded by the WDR5 gene.
WD repeat-containing protein 44 is a protein that in humans is encoded by the WDR44 gene.
Protein SEC13 homolog is a protein that in humans is encoded by the SEC13 gene.
Actin-related protein 2/3 complex subunit 3 is a protein that in humans is encoded by the ARPC3 gene.
Adenylyl cyclase-associated protein 1 is an enzyme that in humans is encoded by the CAP1 gene.
Cdc42 effector protein 1 is a protein that in humans is encoded by the CDC42EP1 gene.
Coronin-1C is a protein that in humans is encoded by the CORO1C gene.
WD repeat-containing protein 36 is a protein that in humans is encoded by the WDR36 gene.
KN motif and ankyrin repeat domain-containing protein 2 is a protein that in humans is encoded by the KANK2 gene.
ATP synthase subunit O, mitochondrial is an enzyme that in humans is encoded by the ATP5PO gene.
KIAA0196 is a human gene. The product is a protein that is a component of the WASH complex, which regulates actin assembly on intracellular vesicles. Mutations in KIAA0196 are implicated in some forms of hereditary spastic paraplegia.
tRNA -methyltransferase subunit WDR4 is an enzyme that in humans is encoded by the WDR4 gene.
WD repeat-containing protein 6 is a protein that in humans is encoded by the WDR6 gene.
Spermatogenesis-defective protein 39 homolog is a protein that in humans is encoded by the VIPAS39 gene. This protein is involved in the sorting of lysosomal proteins. Mutations in this gene are associated with ARCS2. Alternative splicing results in multiple transcript variants.
WD repeat domain phosphoinositide-interacting protein 4 (WIPI-4) is a protein that in humans is encoded by the WDR45 gene. Mutations in this gene cause a distinct form of Neurodegeneration with brain iron accumulation (NBIA).
WD repeat-containing protein 26 is a protein that in humans is encoded by the WDR26 gene.