WDR26

WDR26
Identifiers
Aliases	WDR26 , CDW2, GID7, MIP2, WD repeat domain 26, SKDEAS
External IDs	OMIM: 617424 MGI: 1923825 HomoloGene: 11857 GeneCards: WDR26
Gene location (Human) Chr. Chromosome 1 (human) [1] Band 1q42.11-q42.12 Start 224,385,146 bp [1] End 224,437,033 bp [1]
Gene location (Mouse) Chr. Chromosome 1 (mouse) [2] Band 1|1 H4 Start 181,000,793 bp [2] End 181,039,566 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in sperm secondary oocyte bone marrow cells stromal cell of endometrium cancellous bone cavity of mouth amniotic fluid monocyte thymus blood Top expressed in aortic valve ascending aorta blood parotid gland left lung lobe lacrimal gland vas deferens calvaria supraoptic nucleus bone marrow More reference expression data BioGPS More reference expression data
Orthologs Species Human Mouse Entrez 80232 226757 Ensembl ENSG00000162923 ENSMUSG00000038733 UniProt Q9H7D7 Q8C6G8 RefSeq (mRNA) NM_001115113 NM_025160 NM_001379403 NM_145514 RefSeq (protein) NP_001108585 NP_079436 NP_001366332 NP_663489 NP_001390510 NP_001390511 NP_001390512 NP_001390513 NP_001390514 NP_001390515 NP_001390516 NP_001390517 NP_001390518 Location (UCSC) Chr 1: 224.39 – 224.44 Mb Chr 1: 181 – 181.04 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

WD repeat-containing protein 26 is a protein that in humans is encoded by the WDR26 gene. ^[5]

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. ^[5]

References

1. GRCh38: Ensembl release 89: ENSG00000162923 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000038733 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: WDR26 WD repeat domain 26".

Further reading

• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi: 10.1016/j.cell.2006.09.026 . PMID   17081983. S2CID   7827573.
• Higa LA, Wu M, Ye T, et al. (2006). "CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation". Nat. Cell Biol. 8 (11): 1277–83. doi:10.1038/ncb1490. PMID   17041588. S2CID   22180568.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Zhu Y, Wang Y, Xia C, et al. (2005). "WDR26: a novel Gbeta-like protein, suppresses MAPK signaling pathway". J. Cell. Biochem. 93 (3): 579–87. doi:10.1002/jcb.20175. PMID   15378603. S2CID   86601953.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID   9373149.
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID   8125298.