XTP3-transactivated gene A protein

DCTPP1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2A3Q, 2OIE, 2OIG, 2Q4P
Identifiers
Aliases	DCTPP1 , RS21C6, XTP3TPA, CDA03, XTP3-transactivated gene A protein, dCTP pyrophosphatase 1
External IDs	OMIM: 615840; MGI: 1913672; HomoloGene: 11329; GeneCards: DCTPP1; OMA:DCTPP1 - orthologs
Gene location (Human) Chr. Chromosome 16 (human) [1] Band 16p11.2 Start 30,423,615 bp [1] End 30,430,030 bp [1]
Gene location (Mouse) Chr. Chromosome 7 (mouse) [2] Band 7|7 F3 Start 126,856,131 bp [2] End 126,859,881 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in mucosa of transverse colon rectum parotid gland oocyte gonad mucosa of sigmoid colon endothelial cell nasal epithelium hair follicle pancreatic ductal cell Top expressed in embryo embryo epiblast yolk sac otic placode primitive streak somite ventricular zone medial ganglionic eminence morula More reference expression data BioGPS More reference expression data
Gene ontology Molecular function nucleotide binding pyrophosphatase activity protein binding hydrolase activity magnesium ion binding metal ion binding identical protein binding pyrimidine deoxyribonucleotide binding dCTP diphosphatase activity nucleoside-triphosphate diphosphatase activity Cellular component cytoplasm cytosol nucleus mitochondrion Biological process protein homotetramerization dCTP catabolic process nucleoside triphosphate catabolic process DNA protection dTTP catabolic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 79077 66422 Ensembl ENSG00000179958 ENSMUSG00000042462 UniProt Q9H773 Q9QY93 RefSeq (mRNA) NM_024096 NM_023203 RefSeq (protein) NP_077001 NP_075692 Location (UCSC) Chr 16: 30.42 – 30.43 Mb Chr 7: 126.86 – 126.86 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

dCTP pyrophosphatase 1 is an enzyme that in humans is encoded by the DCTPP1 gene. ^{[5] [6]}

See also

• Deoxycytidine triphosphate (dCTP)
• Transactivation

References

1. GRCh38: Ensembl release 89: ENSG00000179958 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000042462 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Moroz OV, Murzin AG, Makarova KS, Koonin EV, Wilson KS, Galperin MY (Mar 2005). "Dimeric dUTPases, HisE, and MazG belong to a new superfamily of all-alpha NTP pyrophosphohydrolases with potential "house-cleaning" functions". J Mol Biol. 347 (2): 243–55. doi:10.1016/j.jmb.2005.01.030. PMID   15740738.
6. "Entrez Gene: XTP3TPA XTP3-transactivated protein A".

Further reading

• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Stelzl U, Worm U, Lalowski M, et al. (2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957–68. doi: 10.1016/j.cell.2005.08.029 . hdl: 11858/00-001M-0000-0010-8592-0 . PMID   16169070.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID   16189514. S2CID   4427026.