XTP3-transactivated gene A protein

DCTPP1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2A3Q, 2OIE, 2OIG, 2Q4P
Identifiers
Aliases	DCTPP1 , RS21C6, XTP3TPA, CDA03, XTP3-transactivated gene A protein, dCTP pyrophosphatase 1
External IDs	OMIM: 615840 MGI: 1913672 HomoloGene: 11329 GeneCards: DCTPP1
Gene location (Human)
Chr.	Chromosome 16 (human)
End	30,430,030 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	126,859,881 bp
RNA expression pattern
	Top expressed in
	rectum; ; parotid gland; ; oocyte; ; endothelial cell; ; hair follicle; ; pancreatic ductal cell; ; ganglionic eminence; ; kidney tubule; ; human penis; ; islet of Langerhans;
	Top expressed in
	yolk sac; ; otic placode; ; primitive streak; ; somite; ; medial ganglionic eminence; ; morula; ; abdominal wall; ; maxillary prominence; ; endocardial cushion; ; internal carotid artery;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	nucleotide binding ; pyrophosphatase activity ; protein binding ; hydrolase activity ; magnesium ion binding ; metal ion binding ; identical protein binding ; pyrimidine deoxyribonucleotide binding ; dCTP diphosphatase activity ; nucleoside-triphosphate diphosphatase activity ;
Cellular component	cytoplasm ; cytosol ; nucleus ; mitochondrion ;
Biological process	protein homotetramerization ; dCTP catabolic process ; nucleoside triphosphate catabolic process ; DNA protection ; dTTP catabolic process ;
	Sources:Amigo / QuickGO
Orthologs
	79077
	66422
	ENSG00000179958
	ENSMUSG00000042462
	Q9H773
	Q9QY93
	NM_024096
	NM_023203
	NP_077001
	NP_075692
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated January 05, 2024

dCTP pyrophosphatase 1 is an enzyme that in humans is encoded by the DCTPP1 gene.^[5]^[6]

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000179958 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000042462 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Moroz OV, Murzin AG, Makarova KS, Koonin EV, Wilson KS, Galperin MY (Mar 2005). "Dimeric dUTPases, HisE, and MazG belong to a new superfamily of all-alpha NTP pyrophosphohydrolases with potential "house-cleaning" functions". J Mol Biol. 347 (2): 243–55. doi:10.1016/j.jmb.2005.01.030. PMID 15740738.
↑ "Entrez Gene: XTP3TPA XTP3-transactivated protein A".

XTP3-transactivated gene A protein

Contents

See also

Related Research Articles

References

Further reading