YBX2

YBX2
Identifiers
Aliases	YBX2 , CONTRIN, CSDA3, DBPC, MSY2, Y-box binding protein 2
External IDs	OMIM: 611447 MGI: 1096372 HomoloGene: 22942 GeneCards: YBX2
Gene location (Human)
Chr.	Chromosome 17 (human)
End	7,294,639 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	69,941,605 bp
RNA expression pattern
	Top expressed in
	duodenum; ; medulla oblongata; ; rectum; ; skeletal muscle tissue; ; salivary gland; ; minor salivary gland; ; gastrocnemius muscle; ; subcutaneous adipose tissue; ; left uterine tube; ; right lobe of liver;
	Top expressed in
	seminiferous tubule; ; spermatid; ; spermatocyte; ; secondary oocyte; ; interventricular septum; ; brown adipose tissue; ; morula; ; skeletal muscle tissue; ; thymus; ; left colon;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding ; RNA binding ; nucleic acid binding ; DNA-binding transcription factor activity, RNA polymerase II-specific ;
Cellular component	cytoplasm ; nucleus ; fibrillar center ;
Biological process	regulation of transcription, DNA-templated ; translational attenuation ; transcription by RNA polymerase II ; spermatogenesis ; oocyte development ; regulation of transcription by RNA polymerase II ; positive regulation of cold-induced thermogenesis ;
	Sources:Amigo / QuickGO
Orthologs
	51087
	53422
	ENSG00000006047 ; ENSG00000288504
	ENSMUSG00000018554
	Q9Y2T7
	Q9Z2C8
	NM_015982
	NM_016875 ; NM_001347634
	NP_057066
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated January 16, 2024

Y-box-binding protein 2 is a protein that in humans is encoded by the YBX2 gene.^[5]^[6]^[7]

Related Research Articles

Y box binding protein 1 also known as Y-box transcription factor or nuclease-sensitive element-binding protein 1 is a protein that in humans is encoded by the YBX1 gene.

MHC class II regulatory factor RFX1 is a protein that, in humans, is encoded by the RFX1 gene located on the short arm of chromosome 19.

Zinc finger protein RFP is a protein that in humans is encoded by the TRIM27 gene.

DNA-binding protein A is a protein that in humans is encoded by the CSDA gene.

Quaking homolog, KH domain RNA binding (mouse), also known as QKI, is a protein which in humans is encoded by the QKI gene.

TRIO and F-actin-binding protein is a protein that in humans is encoded by the TRIOBP gene.

RNA-binding motif protein, Y chromosome, family 1 member A1/C is a protein that in humans is encoded by the RBMY1A1 gene.

Chorion-specific transcription factor GCMa is a protein that, in humans, is encoded by the GCM1 gene.

TFIIA-alpha and beta-like factor is a protein that in humans is encoded by the GTF2A1L gene.

Neighbor of BRCA1 gene 1 protein is a protein that in humans is encoded by the NBR1 gene.

Target of rapamycin complex 2 subunit MAPKAP1 is a protein that in humans is encoded by the MAPKAP1 gene. As the name indicates, it is a subunit of mTOR complex 2.

Serine/threonine-protein kinase PLK2 is an enzyme that in humans is encoded by the PLK2 gene.

Cold-inducible RNA-binding protein is a protein that in humans is encoded by the CIRBP gene. The cold inducible RNA-binding protein CIRBP plays a critical role in controlling the cellular response upon confronting a variety of cellular stresses, including short wavelength ultraviolet light, hypoxia, and hypothermia.

CDK5 regulatory subunit-associated protein 1 is a protein that in humans is encoded by the CDK5RAP1 gene.

Thyrotroph embryonic factor is a protein that in humans is encoded by the TEF gene.

Calmegin, also known as CLGN, is a protein which in humans is encoded by the CLGN gene. Calmegin is also present in other animals including mice.

Single-stranded DNA-binding protein 2 is a protein that in humans is encoded by the SSBP2 gene.

Forkhead box protein D4 is a protein that in humans is encoded by the FOXD4 gene.

Paired mesoderm homeobox protein 2 is a protein that in humans is encoded by the PRRX2 gene.

High mobility group nucleosome-binding domain-containing protein 3 is a protein that in humans is encoded by the HMGN3 gene.

References

1 2 3 ENSG00000288504 GRCh38: Ensembl release 89: ENSG00000006047, ENSG00000288504 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000018554 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Tekur S, Pawlak A, Guellaen G, Hecht NB (Jul 1999). "Contrin, the human homologue of a germ-cell Y-box-binding protein: cloning, expression, and chromosomal localization". J Androl. 20 (1): 135–44. doi:10.1002/j.1939-4640.1999.tb02506.x. PMID 10100484.
↑ Gu W, Tekur S, Reinbold R, Eppig JJ, Choi YC, Zheng JZ, Murray MT, Hecht NB (Dec 1998). "Mammalian male and female germ cells express a germ cell-specific Y-Box protein, MSY2". Biol Reprod. 59 (5): 1266–74. doi: 10.1095/biolreprod59.5.1266 . PMID 9780336.
↑ "Entrez Gene: YBX2 Y box binding protein 2".

Hammoud S, Emery BR, Dunn D, et al. (2009). "Sequence alterations in the YBX2 gene are associated with male factor infertility". Fertil. Steril. 91 (4): 1090–5. doi: 10.1016/j.fertnstert.2008.01.009 . PMID 18339382.
Yoshida T, Izumi H, Uchiumi T, et al. (2006). "Expression and cellular localization of dbpC/Contrin in germ cell tumor cell lines". Biochim. Biophys. Acta. 1759 (1–2): 80–8. doi:10.1016/j.bbaexp.2006.02.005. PMID 16624424.
Kohno Y, Matsuki Y, Tanimoto A, et al. (2006). "Expression of Y-box-binding protein dbpC/contrin, a potentially new cancer/testis antigen". Br. J. Cancer. 94 (5): 710–6. doi:10.1038/sj.bjc.6602987. PMC 2361212 . PMID 16479255.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129 . PMID 16344560.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.

This article on a gene on human chromosome 17 is a stub. You can help Wikipedia by expanding it.

This page is based on this Wikipedia article
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.

[refGRCh38Ensembl-1] 1 2 3 ENSG00000288504 GRCh38: Ensembl release 89: ENSG00000006047, ENSG00000288504 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000018554 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10100484-5] Tekur S, Pawlak A, Guellaen G, Hecht NB (Jul 1999). "Contrin, the human homologue of a germ-cell Y-box-binding protein: cloning, expression, and chromosomal localization". J Androl. 20 (1): 135–44. doi:10.1002/j.1939-4640.1999.tb02506.x. PMID 10100484.

[pmid9780336-6] Gu W, Tekur S, Reinbold R, Eppig JJ, Choi YC, Zheng JZ, Murray MT, Hecht NB (Dec 1998). "Mammalian male and female germ cells express a germ cell-specific Y-Box protein, MSY2". Biol Reprod. 59 (5): 1266–74. doi: 10.1095/biolreprod59.5.1266 . PMID 9780336.

[entrez-7] "Entrez Gene: YBX2 Y box binding protein 2".

[1]

[2]

[3]

[4]

[5]

[6]

[7]

YBX2

Contents

See also

Related Research Articles

References

Further reading