ZBED3

ZBED3
Identifiers
Aliases	ZBED3 , zinc finger BED-type containing 3
External IDs	OMIM: 615250 MGI: 1919364 HomoloGene: 12442 GeneCards: ZBED3
Gene location (Human)
Chr.	Chromosome 5 (human)
End	77,087,285 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	95,337,841 bp
Gene ontology
Molecular function	• DNA binding ; • metal ion binding ; • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific ;
Cellular component	• cytoplasm ; • membrane ; • cytosol ;
Biological process	• positive regulation of canonical Wnt signaling pathway ; • negative regulation of protein phosphorylation ; • protein stabilization ; • Wnt signaling pathway ; • positive regulation of transcription by RNA polymerase II ;
	Sources:Amigo / QuickGO
Orthologs
	84327
	72114
	ENSG00000132846
	ENSMUSG00000041995
	Q96IU2
	Q9D0L1
	NM_032367 ; NM_001329564
	NM_028106 ; NM_001302538 ; NM_001302539
	NP_001316493 ; NP_115743
	NP_001289467 ; NP_001289468 ; NP_082382
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated September 25, 2021

Zinc finger BED domain-containing protein 3 also known as axin-interacting protein is a protein in humans that is encoded by the ZBED3 gene.^[5]

Related Research Articles

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000132846 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000041995 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: Zinc finger, BED-type containing 3".

Hayward A, Ghazal A, Andersson G, Andersson L, Jern P (2013). Robinson-Rechavi M (ed.). "ZBED evolution: repeated utilization of DNA transposons as regulators of diverse host functions". PLOS ONE. 8 (3): e59940. Bibcode:2013PLoSO...859940H. doi: 10.1371/journal.pone.0059940 . PMC 3606216 . PMID 23533661.
de Miguel-Yanes JM, Shrader P, Pencina MJ, Fox CS, Manning AK, Grant RW, Dupuis J, Florez JC, D'Agostino RB, Cupples LA, Meigs JB (Jan 2011). "Genetic risk reclassification for type 2 diabetes by age below or above 50 years using 40 type 2 diabetes risk single nucleotide polymorphisms" (PDF). Diabetes Care. 34 (1): 121–5. doi:10.2337/dc10-1265. PMC 3005447 . PMID 20889853.
Chen T, Li M, Ding Y, Zhang LS, Xi Y, Pan WJ, Tao DL, Wang JY, Li L (Mar 2009). "Identification of zinc-finger BED domain-containing 3 (Zbed3) as a novel Axin-interacting protein that activates Wnt/beta-catenin signaling". The Journal of Biological Chemistry. 284 (11): 6683–9. doi: 10.1074/jbc.M807753200 . PMC 2652294 . PMID 19141611.
Voight BF, Scott LJ, Steinthorsdottir V, Morris AP, Dina C, Welch RP, Zeggini E, Huth C, et al. (Jul 2010). "Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis". Nature Genetics. 42 (7): 579–89. doi:10.1038/ng.609. PMC 3080658 . PMID 20581827.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000132846 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000041995 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Zinc finger, BED-type containing 3".

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ZBED3

Related Research Articles

References

Further reading