ZBED6

ZBED6
Identifiers
Aliases	ZBED6 , MGR, zinc finger BED-type containing 6
External IDs	OMIM: 613512 MGI: 3828086 HomoloGene: 130066 GeneCards: ZBED6
Gene location (Human) Chr. Chromosome 1 (human) [1] Band 1q32.1 Start 203,795,714 bp [1] End 203,854,999 bp [1]
Gene location (Mouse) Chr. Chromosome 1 (mouse) [2] Band 1|1 E4 Start 133,547,678 bp [2] End 133,589,056 bp [2]
RNA expression pattern Bgee Top expressed in stomach kidney lung heart corpus callosum colon Achilles tendon liver More reference expression data BioGPS n/a
Gene ontology Molecular function DNA binding protein dimerization activity metal ion binding GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity RNA polymerase II transcription regulatory region sequence-specific DNA binding GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component nucleolus nucleus Biological process negative regulation of transcription, DNA-templated regulation of transcription, DNA-templated transcription, DNA-templated regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	100381270	667118
Ensembl	ENSG00000257315	ENSMUSG00000094410
UniProt	P86452	D2EAC2
RefSeq (mRNA)	NM_001174108 NM_001395895	NM_001166552 NM_001395904
RefSeq (protein)	NP_001167579	NP_001160024 NP_001382833
Location (UCSC)	Chr 1: 203.8 – 203.85 Mb	Chr 1: 133.55 – 133.59 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

Zinc finger, BED-type containing 6 is a protein that in humans is encoded by the ZBED6 gene. ^[5]

References

1. GRCh38: Ensembl release 89: ENSG00000257315 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000094410 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: Zinc finger, BED-type containing 6" . Retrieved 2012-03-15.

Further reading

• Markljung E, Jiang L, Jaffe JD, Mikkelsen TS, Wallerman O, Larhammar M, Zhang X, Wang L, Saenz-Vash V, Gnirke A, Lindroth AM, Barrés R, Yan J, Strömberg S, De S, Pontén F, Lander ES, Carr SA, Zierath JR, Kullander K, Wadelius C, Lindblad-Toh K, Andersson G, Hjälm G, Andersson L (Dec 2009). O'Rahilly S (ed.). "ZBED6, a novel transcription factor derived from a domesticated DNA transposon regulates IGF2 expression and muscle growth". PLOS Biology. 7 (12): e1000256. doi:10.1371/journal.pbio.1000256. PMC   2780926 . PMID   20016685.
• Butter F, Kappei D, Buchholz F, Vermeulen M, Mann M (Apr 2010). "A domesticated transposon mediates the effects of a single-nucleotide polymorphism responsible for enhanced muscle growth". EMBO Reports. 11 (4): 305–11. doi:10.1038/embor.2010.6. PMC   2854606 . PMID   20134481.
• Andersson L (2010). "Studying phenotypic evolution in domestic animals: a walk in the footsteps of Charles Darwin". Cold Spring Harbor Symposia on Quantitative Biology. 74: 319–25. doi: 10.1101/sqb.2009.74.039 . PMID   20375320.