ZDHHC4

ZDHHC4
Identifiers
Aliases	ZDHHC4 , ZNF374, zinc finger DHHC-type containing 4
External IDs	MGI: 1920131; HomoloGene: 10006; GeneCards: ZDHHC4; OMA:ZDHHC4 - orthologs
Gene location (Human) Chr. Chromosome 7 (human) [1] Band 7p22.1 Start 6,577,434 bp [1] End 6,589,374 bp [1]
Gene location (Mouse) Chr. Chromosome 5 (mouse) [2] Band 5|5 G2 Start 143,316,489 bp [2] End 143,329,256 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in left testis right testis islet of Langerhans body of pancreas stromal cell of endometrium muscle layer of sigmoid colon gastric mucosa gastrocnemius muscle body of stomach right adrenal cortex Top expressed in spermatocyte spermatid seminiferous tubule right kidney interventricular septum lip muscle of thigh granulocyte otic vesicle saccule More reference expression data BioGPS More reference expression data
Gene ontology Molecular function acyltransferase activity protein-cysteine S-palmitoyltransferase activity transferase activity Cellular component Golgi apparatus membrane integral component of membrane endoplasmic reticulum endoplasmic reticulum membrane Biological process protein targeting to membrane peptidyl-L-cysteine S-palmitoylation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55146 72881 Ensembl ENSG00000136247 ENSMUSG00000001844 UniProt Q9NPG8 Q9D6H5 RefSeq (mRNA) NM_001134387 NM_001134388 NM_001134389 NM_018106 NM_028379 NM_001359445 RefSeq (protein) NP_001127859 NP_001127860 NP_001127861 NP_060576 NP_001358221 NP_001358222 NP_001358223 NP_001358224 NP_001358225 NP_001358226 NP_001358227 NP_001358228 NP_082655 NP_001346374 Location (UCSC) Chr 7: 6.58 – 6.59 Mb Chr 5: 143.32 – 143.33 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Probable palmitoyltransferase ZDHHC4 is an enzyme that in humans is encoded by the ZDHHC4 gene. ^[5]

See also

• Chromosome 7 (human)
• Cytochrome c oxidase
• DHHC domain

References

1. GRCh38: Ensembl release 89: ENSG00000136247 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000001844 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: ZDHHC4 zinc finger, DHHC-type containing 4".

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID   8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID   9373149.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC   311072 . PMID   11230166.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology". Science. 300 (5620): 767–72. Bibcode:2003Sci...300..767S. doi:10.1126/science.1083423. PMC   2882961 . PMID   12690205.
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC   403697 . PMID   12975309.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Grimsby S, Jaensson H, Dubrovska A, et al. (2005). "Proteomics-based identification of proteins interacting with Smad3: SREBP-2 forms a complex with Smad3 and inhibits its transcriptional activity". FEBS Lett. 577 (1–2): 93–100. doi: 10.1016/j.febslet.2004.09.069 . PMID   15527767. S2CID   82568.