ZDHHC9

ZDHHC9
Identifiers
Aliases	ZDHHC9 , CGI89, CXorf11, DHHC9, MMSA1, MRXSZ, ZDHHC10, ZNF379, ZNF380, zinc finger DHHC-type containing 9, zinc finger DHHC-type palmitoyltransferase 9, MRXSR
External IDs	OMIM: 300646 MGI: 2444393 HomoloGene: 91149 GeneCards: ZDHHC9
Gene location (Human)
Chr.	X chromosome (human)
End	129,843,909 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	47,297,755 bp
RNA expression pattern
	Top expressed in
	corpus callosum; ; inferior ganglion of vagus nerve; ; external globus pallidus; ; subthalamic nucleus; ; internal globus pallidus; ; ventral tegmental area; ; pons; ; medulla oblongata; ; Stromal cell of endometrium; ; Brodmann area 46;
	Top expressed in
	esophagus; ; lip; ; left lobe of liver; ; ileum; ; intestinal villus; ; crypt of lieberkuhn of small intestine; ; yolk sac; ; Ankle joint; ; fossa; ; corneal stroma;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein-cysteine S-palmitoyltransferase activity ; Ras palmitoyltransferase activity ; transferase activity ; acyltransferase activity ; protein binding ; palmitoyltransferase activity ;
Cellular component	integral component of membrane ; palmitoyltransferase complex ; Golgi membrane ; Golgi apparatus ; intrinsic component of Golgi membrane ; endoplasmic reticulum membrane ; endoplasmic reticulum ; membrane ; cytosol ;
Biological process	peptidyl-L-cysteine S-palmitoylation ; protein palmitoylation ; protein targeting to membrane ;
	Sources:Amigo / QuickGO
Orthologs
	51114
	208884
	ENSG00000188706
	ENSMUSG00000036985
	Q9Y397
	P59268
	NM_001008222 ; NM_016032
	NM_172465
	NP_001008223 ; NP_057116
	NP_766053
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated September 05, 2022

Palmitoyltransferase ZDHHC9 is an enzyme that in humans is encoded by the ZDHHC9 gene that contains a DHHC domain.^[5]^[6]

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000188706 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000036985 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (Aug 2000). "Identification of Novel Human Genes Evolutionarily Conserved in Caenorhabditis elegans by Comparative Proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876 . PMID 10810093.
↑ "Entrez Gene: ZDHHC9 zinc finger, DHHC-type containing 9".

Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Clark HF, Gurney AL, Abaya E, et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697 . PMID 12975309.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–45. doi: 10.1038/ng1285 . PMID 14702039.
Fu GK, Wang JT, Yang J, et al. (2005). "Circular rapid amplification of cDNA ends for high-throughput extension cloning of partial genes". Genomics. 84 (1): 205–10. doi:10.1016/j.ygeno.2004.01.011. PMID 15203218.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–27. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome". Nature. 434 (7031): 325–37. Bibcode:2005Natur.434..325R. doi:10.1038/nature03440. PMC 2665286 . PMID 15772651.
Swarthout JT, Lobo S, Farh L, et al. (2005). "DHHC9 and GCP16 constitute a human protein fatty acyltransferase with specificity for H- and N-Ras". J. Biol. Chem. 280 (35): 31141–48. doi: 10.1074/jbc.M504113200 . PMID 16000296.
Raymond FL, Tarpey PS, Edkins S, et al. (2007). "Mutations in ZDHHC9, Which Encodes a Palmitoyltransferase of NRAS and HRAS, Cause X-Linked Mental Retardation Associated with a Marfanoid Habitus". Am. J. Hum. Genet. 80 (5): 982–87. doi:10.1086/513609. PMC 1852737 . PMID 17436253.
Mansilla F, Birkenkamp-Demtroder K, Kruhøffer M, et al. (2007). "Differential expression of DHHC9 in microsatellite stable and instable human colorectal cancer subgroups". Br. J. Cancer. 96 (12): 1896–903. doi:10.1038/sj.bjc.6603818. PMC 2359975 . PMID 17519897.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000188706 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000036985 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10810093-5] Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (Aug 2000). "Identification of Novel Human Genes Evolutionarily Conserved in Caenorhabditis elegans by Comparative Proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876 . PMID 10810093.

[entrez-6] "Entrez Gene: ZDHHC9 zinc finger, DHHC-type containing 9".

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ZDHHC9

Related Research Articles

References

Further reading