ZFAND5

ZFAND5
Identifiers
Aliases	ZFAND5 , ZA20D2, ZFAND5A, ZNF216, zinc finger AN1-type containing 5
External IDs	OMIM: 604761 MGI: 1278334 HomoloGene: 21215 GeneCards: ZFAND5
Gene location (Human) Chr. Chromosome 9 (human) [1] Band 9q21.13 Start 72,351,413 bp [1] End 72,365,235 bp [1]
Gene location (Mouse) Chr. Chromosome 19 (mouse) [2] Band 19 B|19 14.32 cM Start 21,249,642 bp [2] End 21,264,204 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gastric mucosa seminal vesicula right lung oocyte tibial nerve tibia biceps brachii popliteal artery secondary oocyte postcentral gyrus Top expressed in habenula extensor digitorum longus muscle triceps brachii muscle plantaris muscle vastus lateralis muscle sternocleidomastoid muscle thoracic diaphragm digastric muscle supraoptic nucleus temporal muscle More reference expression data BioGPS n/a
Gene ontology Molecular function DNA binding zinc ion binding protein binding metal ion binding molecular function Cellular component cytoplasm cellular component Biological process fibroblast migration skeletal system morphogenesis platelet-derived growth factor receptor signaling pathway face development respiratory system process vasculature development in utero embryonic development smooth muscle tissue development biological process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 7763 22682 Ensembl ENSG00000107372 ENSMUSG00000024750 UniProt O76080 O88878 RefSeq (mRNA) NM_006007 NM_001102420 NM_001102421 NM_001278243 NM_001278244 NM_001278245 NM_009551 RefSeq (protein) NP_001095890 NP_001095891 NP_001265172 NP_001265173 NP_001265174 NP_005998 NP_033577 Location (UCSC) Chr 9: 72.35 – 72.37 Mb Chr 19: 21.25 – 21.26 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Zinc finger AN1-type containing 5 is a protein that in humans is encoded by the ZFAND5 gene. ^[5]

References

1. GRCh38: Ensembl release 89: ENSG00000107372 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000024750 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: Zinc finger AN1-type containing 5" . Retrieved 2020-04-12.

Further reading

• Huang J, Teng L, Li L, Liu T, Li L, Chen D, Xu LG, Zhai Z, Shu HB (April 2004). "ZNF216 Is an A20-like and IkappaB kinase gamma-interacting inhibitor of NFkappaB activation". J. Biol. Chem. 279 (16): 16847–53. doi: 10.1074/jbc.M309491200 . PMID   14754897.
• Hishiya A, Ikeda K, Watanabe K (2005). "A RANKL-inducible gene Znf216 in osteoclast differentiation". J. Recept. Signal Transduct. Res. 25 (3): 199–216. doi:10.1080/10799890500240781. PMID   16194934. S2CID   11227257.
• Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD (November 2009). "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip". Am. J. Hum. Genet. 85 (5): 628–42. doi:10.1016/j.ajhg.2009.10.014. PMC   2775832 . PMID   19913121.
• Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S (October 2010). "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study". Diabetes Care. 33 (10): 2250–3. doi:10.2337/dc10-0452. PMC   2945168 . PMID   20628086.
• He G, Sun D, Ou Z, Ding A (July 2012). "The protein Zfand5 binds and stabilizes mRNAs with AU-rich elements in their 3'-untranslated regions". J. Biol. Chem. 287 (30): 24967–77. doi: 10.1074/jbc.M112.362020 . PMC   3408148 . PMID   22665488.