ZGPAT

ZGPAT
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4II1
Identifiers
Aliases	ZGPAT , GPATC6, GPATCH6, KIAA1847, ZC3H9, ZC3HDC9, ZIP, zinc finger CCCH-type and G-patch domain containing
External IDs	MGI: 2449939; HomoloGene: 41874; GeneCards: ZGPAT; OMA:ZGPAT - orthologs
Gene location (Human) Chr. Chromosome 20 (human) [1] Band 20q13.33 Start 63,707,465 bp [1] End 63,736,142 bp [1]
Gene location (Mouse) Chr. Chromosome 2 (mouse) [2] Band 2|2 H4 Start 181,006,721 bp [2] End 181,025,421 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right lobe of liver granulocyte blood sural nerve spleen apex of heart monocyte mucosa of transverse colon human kidney right hemisphere of cerebellum Top expressed in bronchus hypothalamus cerebellar cortex olfactory bulb mesencephalon superior frontal gyrus primary visual cortex lens striatum of neuraxis neural tube More reference expression data BioGPS More reference expression data
Gene ontology Molecular function DNA-binding transcription factor activity RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding DNA binding DNA-binding transcription repressor activity, RNA polymerase II-specific protein binding metal ion binding nucleic acid binding DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component nucleus plasma membrane Biological process negative regulation of epidermal growth factor-activated receptor activity negative regulation of transcription, DNA-templated regulation of transcription, DNA-templated negative regulation of transcription by RNA polymerase II transcription, DNA-templated Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 84619 229007 Ensembl ENSG00000197114 ENSMUSG00000027582 UniProt Q8N5A5 Q8VDM1 RefSeq (mRNA) NM_181485 NM_001083113 NM_001195653 NM_001195654 NM_032527 NM_181484 NM_001048148 NM_144894 RefSeq (protein) NP_001076582 NP_001182582 NP_001182583 NP_115916 NP_852150 NP_001041613 NP_659143 Location (UCSC) Chr 20: 63.71 – 63.74 Mb Chr 2: 181.01 – 181.03 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Zinc finger CCCH-type with G patch domain-containing protein is a protein that in humans is encoded by the ZGPAT gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000197114 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000027582 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Ordway JM, Bedell JA, Citek RW, Nunberg A, Garrido A, Kendall R, Stevens JR, Cao D, Doerge RW, Korshunova Y, Holemon H, McPherson JD, Lakey N, Leon J, Martienssen RA, Jeddeloh JA (Nov 2006). "Comprehensive DNA methylation profiling in a human cancer genome identifies novel epigenetic targets". Carcinogenesis. 27 (12): 2409–23. doi: 10.1093/carcin/bgl161 . PMID   16952911.
6. "Entrez Gene: ZGPAT zinc finger, CCCH-type with G patch domain".

Further reading

• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi: 10.1016/j.cell.2006.09.026 . PMID   17081983. S2CID   7827573.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC   1356129 . PMID   16344560.
• Rual JF, Hirozane-Kishikawa T, Hao T, et al. (2004). "Human ORFeome Version 1.1: A Platform for Reverse Proteomics". Genome Res. 14 (10B): 2128–35. doi:10.1101/gr.2973604. PMC   528929 . PMID   15489335.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Deloukas P, Matthews LH, Ashurst J, et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. Bibcode:2001Natur.414..865D. doi: 10.1038/414865a . PMID   11780052.
• Nagase T, Nakayama M, Nakajima D, et al. (2001). "Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 8 (2): 85–95. doi: 10.1093/dnares/8.2.85 . PMID   11347906.