DNA-directed RNA polymerase I subunit RPA12 is an enzyme that in humans is encoded by the ZNRD1 gene. [5] [6] [7]
This gene encodes a protein with similarity to the Saccharomyces cerevisiae Rpa12p subunit of RNA polymerase I. Alternate splicing of this gene results in two transcript variants encoding the same protein. Additional splice variants have been described, but their full-length sequences have not been determined. [7]
Runt-related transcription factor 3 is a protein that in humans is encoded by the RUNX3 gene.
HLA class I histocompatibility antigen, alpha chain F is a protein that in humans is encoded by the HLA-F gene. It is an empty intracellular molecule that encodes a non-classical heavy chain anchored to the membrane and forming a heterodimer with a β-2 microglobulin light chain. It belongs to the HLA class I heavy chain paralogues that separate from most of the HLA heavy chains. HLA-F is localized in the endoplasmic reticulum and Golgi apparatus, and is also unique in the sense that it exhibits few polymorphisms in the human population relative to the other HLA genes; however, there have been found different isoforms from numerous transcript variants found for the HLA-F gene. Its pathways include INF-gamma signaling and CDK-mediated phosphorylation and removal of the Saccharomycescerevisiae Cdc6 protein, which is crucial for functional DNA replication.
Metastasis-associated protein MTA2 is a protein that in humans is encoded by the MTA2 gene.
Zinc finger homeobox protein 3 is a protein that in humans is encoded by the ZFHX3 gene.
Zinc finger protein 165 is a protein that in humans is encoded by the ZNF165 gene.
E3 ubiquitin-protein ligase RNF5 is an enzyme that in humans is encoded by the RNF5 gene.
60S ribosomal protein L23 is a protein that in humans is encoded by the RPL23 gene.
Metastasis-associated protein MTA3 is a protein that in humans is encoded by the MTA3 gene. MTA3 protein localizes in the nucleus as well as in other cellular compartments MTA3 is a component of the nucleosome remodeling and deacetylate (NuRD) complex and participates in gene expression. The expression pattern of MTA3 is opposite to that of MTA1 and MTA2 during mammary gland tumorigenesis. However, MTA3 is also overexpressed in a variety of human cancers.
Protein phosphatase 1 regulatory subunit 11 is an enzyme that in humans is encoded by the PPP1R11 gene.
Zinc transporter SLC39A7 (ZIP7), also known as solute carrier family 39 member 7, is a protein that in humans is encoded by the SLC39A7 gene. Its fruit fly orthologue is Catsup.
Protein odd-skipped-related 1 is a transcription factor that in humans is encoded by the OSR1 gene. The OSR1 and OSR2 transcription factors participate in the normal development of body parts such as the kidney.
Zinc finger protein 24 is a protein that in humans is encoded by the ZNF24 gene.
Zinc transporter ZIP6 is a protein that in humans is encoded by the SLC39A6 gene.
PHD finger protein 1 is a protein that in humans is encoded by the PHF1 gene.
RING finger protein 39 is a protein that in humans is encoded by the RNF39 gene.
In molecular biology, ZNRD1 antisense RNA 1, also known as ZNRD1-AS1 or HTEX4, is a long non-coding RNA. In humans, it is located in the MHC class I region of chromosome 6. It is expressed in testis and is alternatively spliced.
LIM zinc finger domain containing 2 is a protein that in humans is encoded by the LIMS2 gene.
Forkhead box O6 is a protein that in humans is encoded by the FOXO6 gene.
MicroRNA 495 is a protein that in humans is encoded by the MIR495 gene.
MicroRNA 141 is a non-coding RNA molecule that in humans is encoded by the MIR141 gene.