Zeta Surgical

Last updated
Zeta Surgical Inc.
Company type Private
IndustryMedical devices
Founded2018
FoundersJose Amich (CEO), Raahil Sha (CTO), William Gormley
Headquarters Boston, Massachusetts, United States
ProductsSurgical navigation
Website https://zetasurgical.com

Zeta Surgical is a privately held American medical technology company based in Boston, Massachusetts. The company develops computer-assisted surgery systems for neurosurgery and interventional neuroradiology. The company was founded in 2018 by Harvard University graduates Jose Amich and Raahil Sha, along with Brigham and Women's Hospital neurosurgeon William Gormley. [1] [2]

Contents

Technology

Zeta Surgical's technology employs computer vision and artificial intelligence algorithms for real-time surgical navigation. The company's approach utilizes parallel computing for image registration and patient tracking without rigid head fixation. Preclinical studies have evaluated the system's ability to maintain submillimeter accuracy in applications such as neurotrauma, intracerebral hemorrhage and brain biopsy. [3] [4] [5]

The company's primary product, the Zeta Cranial Navigation System, has been described as a "GPS-like" system for neurosurgery. [1] It received 510(k) clearance from the US Food and Drug Administration for use in cranial surgical procedures in September 2023. [6] [7] [8] In 2024, Zeta Surgical reported the completion of its first multi-center trial at Singapore General Hospital and Tan Tock Seng Hospital. [9] The Zeta Cranial Navigation System received an iF Design Award and a Good Design Award in 2023. [10] [11] The company is partnered with Australian product design and consultancy firm Design + Industry. [12]

In 2022, Zeta Surgical announced that it was developing a Focused ultrasound for intracranial drug delivery system, navigated by the Zeta Cranial Navigation System. [13] The company is a member of the Focused Ultrasound Foundation. [14]

History

Zeta Surgical was started by Jose Amich and Raahil Sha while studying as undergraduate students at Harvard University, together with Harvard Medical School professor William Gormley, also a neurosurgeon at the Brigham and Women's Hospital. [15] Jose Amich and William Gormley are alumni of the MIT Sloan School of Management MBA program. [16] [17] The company has raised funding from notable investors such as Y Combinator, Artesian Hostplus VC, Innospark Ventures, Trevor Fetter, Gabriel Hammond and Marc de Garidel. [18] [15] Zeta Surgical is represented by law firm White & Case LLP. [19]

Raahil Sha was named one of Harvard's Most Interesting Seniors. [20] Together with Jose Amich, they have been recognized on the North American Forbes 30 Under 30 2024 list. [2]

Related Research Articles

<span class="mw-page-title-main">Neurosurgery</span> Medical specialty of disorders which affect any portion of the nervous system.

Neurosurgery or neurological surgery, known in common parlance as brain surgery, is the medical specialty concerned with the surgical treatment of disorders which affect any portion of the nervous system including the brain, spinal cord and peripheral nervous system.

Sonicaid Ltd was a medical electronics company headquartered in West Sussex best known for its range of Doppler fetal monitors. The company also developed early ultrasound scanners. The word "Sonicaid" is in generic use for Doppler fetal monitors. Sonicaid is now a registered trademark of Huntleigh Healthcare.

Image-guided surgery (IGS) is any surgical procedure where the surgeon uses tracked surgical instruments in conjunction with preoperative or intraoperative images in order to directly or indirectly guide the procedure. Image guided surgery systems use cameras, ultrasonic, electromagnetic or a combination of fields to capture and relay the patient's anatomy and the surgeon's precise movements in relation to the patient, to computer monitors in the operating room or to augmented reality headsets. This is generally performed in real-time though there may be delays of seconds or minutes depending on the modality and application.

INSIGHTEC Ltd., is a privately held medical device company that sells MR guided Focused Ultrasound equipment. The technology can destroy deep tissue in the body without the need for incisions.

OsteoMed L.P., formerly known as OsteoMed Corporation, is a medical device manufacturer specializing in craniofacial titanium fixation, small bone drills and saws, and a variety of implantable devices used in foot and ankle surgery. OsteoMed's focus is on neurosurgery, reconstructive plastic surgery, oral surgery, podiatry, and foot and ankle orthopedics.

Total disc replacement (TDR), or artificial disc replacement (ADR), is a type of arthroplasty in which degenerated intervertebral discs in the vertebral column are replaced with artificial disc implants in the lumbar (lower) or cervical (upper) spine. The procedure is used to treat chronic, severe low back pain and cervical pain resulting from degenerative disc disease. Disc replacement is also an alternative intervention for symptomatic disc herniation with associated arm and hand, or leg symptoms.

Computer-assisted surgery (CAS) represents a surgical concept and set of methods, that use computer technology for surgical planning, and for guiding or performing surgical interventions. CAS is also known as computer-aided surgery, computer-assisted intervention, image-guided surgery, digital surgery and surgical navigation, but these are terms that are more or less synonymous with CAS. CAS has been a leading factor in the development of robotic surgery.

<span class="mw-page-title-main">Surgical planning</span>

Surgical planning is the preoperative method of pre-visualising a surgical intervention, in order to predefine the surgical steps and furthermore the bone segment navigation in the context of computer-assisted surgery. The surgical planning is most important in neurosurgery and oral and maxillofacial surgery. The transfer of the surgical planning to the patient is generally made using a medical navigation system.

da Vinci Surgical System Robotic surgical system

The da Vinci Surgical System is a robotic surgical system that uses a minimally invasive surgical approach. The system is manufactured by the company Intuitive Surgical. The system is used for prostatectomies, increasingly for cardiac valve repair and for renal and gynecologic surgical procedures.

<span class="mw-page-title-main">ADAC Laboratories</span>

ADAC Laboratories was a Silicon Valley medical device company specialising in nuclear medicine gamma camera manufacturing and associated nuclear medicine processing computers and software. It was originally located at 10300 Bubb Road, Cupertino, California, 95014, then as the company expanded moved in turn to the following locations. 4747 Hellyer Avenue, San Jose, CA 951, then 255 San Geronimo Way, Sunnyvale, CA, then from ~1993, 540 Alder Drive Milpitas, CA 95035. Although most people called the company ADAC or adaclabs, the name ADAC was an acronym of Analytical Development Associates Corporation. It was incorporated in California on October 14, 1970.

<span class="mw-page-title-main">Nicholas Theodore</span> American neurosurgeon

Nicholas Theodore is an American neurosurgeon and researcher at Johns Hopkins University School of Medicine. He is known for his work in spinal trauma, minimally invasive surgery, robotics, and personalized medicine. He is Director of the Neurosurgical Spine Program at Johns Hopkins and Co-Director of the Carnegie Center for Surgical Innovation at Johns Hopkins.

<span class="mw-page-title-main">ROSA</span>

ROSA is a medical robotic technology, designed to minimize invasiveness of surgeries of the central nervous system. ROSA robots assist health professionals during surgical procedures.

<span class="mw-page-title-main">Mazor Robotics</span>

Mazor Robotics was an Israeli medical device company and manufacturer of a robotic guidance system for spine surgery that was acquired by Medtronic in December 2018. Surgeons that utilized Mazor Robotics Renaissance generally specialize in orthopedic surgery or neurosurgery.

The Dextroscope is a medical equipment system that creates a virtual reality (VR) environment in which surgeons can plan neurosurgical and other surgical procedures.

Volume Interactions Pte Ltd was a company that pioneered in the 1990s the use Virtual Reality technology in surgery planning. The company created and marketed the Dextroscope, the first commercial surgical planning system that used virtual reality principles going beyond the mouse and keyboard. The Dextroscope introduced a variation of Virtual Reality technology that didn't use Head-Mounted display that provided a natural and comfortable interface to work with multi-modality 3D medical images for long periods of time. This environment was applied to the planning of patient-specific surgical approaches for several clinical disciplines, including neurosurgery, Ear-Nose-Throat, and liver surgery. The Dextroscope received world-wide attention by being involved in the planning of several craniopagus twin separations, most notably the Zambian twins (1997) and the German twins (2004) at Johns Hopkins Hospital led by Dr Benjamin Carson, and the Nepali twins separation at the Singapore General Hospital in 2001.

Neuroplastic or neuroplastic and reconstructive surgery is the surgical specialty involved in reconstruction or restoration of patients who undergo surgery of the central or peripheral nervous system. The field includes a wide variety of surgical procedures that seek to restore or replace a patient's skull, face, scalp, dura, the spine and/or its overlying tissues.

<span class="mw-page-title-main">Integra LifeSciences</span> Device manufacturing company

Integra LifeSciences Holdings Corporation is a global medical device manufacturing company headquartered in Princeton, New Jersey. Founded in 1989, the company manufactures products for skin regeneration, neurosurgery, reconstructive and general surgery. Integra artificial skin became the first commercially reproducible skin tissue used to treat severe burns and other skin wounds.

<span class="mw-page-title-main">Claire Karekezi</span> Rwandan neurosurgeon

Claire Karekezi is a Rwandan neurosurgeon at the Rwanda Military Referral and Teaching Hospital in Kigali, Rwanda. As the first female neurosurgeon in Rwanda, and one of the eight Rwandan neurosurgeons serving a population of 14 million, Karekezi serves as an advocate for women in neurosurgery. She has become an inspiration for young people pursuing neurosurgery, particularly young women.

<span class="mw-page-title-main">Aroa Biosurgery</span> Regenerative medicine company background

Aroa Biosurgery Limited is a regenerative medicine company that develops, manufactures and distributes products for wound healing and soft tissue reconstruction. Aroa Biosurgery is headquartered in Auckland, New Zealand with a US office in San Diego, CA, USA and is listed on the Australian Securities Exchange. The company, originally known as Mesynthes Limited, was founded in 2008 by Veterinarian Surgeon Dr Brian Ward (BVSc). The company develops and commercializes products based on its proprietary ovine forestomach matrix technology platform with products in wound healing as well as plastics and reconstructive surgery and repair of hernia.

<span class="mw-page-title-main">Amir Manbachi</span> Iranian-Canadian academic and researcher

Amir Manbachi is an Iranian-born, Canadian-American academic and researcher, currently working as an Associate Professor of Neurosurgery and Biomedical Engineering at Johns Hopkins School of Medicine, and known for his work in Medical Ultrasound. He is the co-founder and current director of HEPIUS Innovation Lab at Johns Hopkins University.

References

  1. 1 2 Park, Andrea (13 September 2023). "Zeta Surgical zeroes in on FDA nod for 'GPS-like' neurosurgery navigation system". Fierce Biotech. Retrieved 13 June 2024. Zeta Surgical is zeroing in on an FDA clearance for its GPS-like neurosurgery navigation system
  2. 1 2 "30 Under 30 North America: Jose Amich and Raahil Sha". Forbes. 28 November 2023. Retrieved 13 June 2024.
  3. ↑ Chiurillo, I.; Sha, R. M.; Robertson, F. C. (2023). "High-Accuracy Neuro-Navigation with Computer Vision for Frameless Registration and Real-Time Tracking". Bioengineering. 10 (12): 1401. doi: 10.3390/bioengineering10121401 .
  4. ↑ Robertson, F. C.; Sha, R. M.; Amich, J. M. (2021). "Frameless neuronavigation with computer vision and real-time tracking for bedside external ventricular drain placement: a cadaveric study". Journal of Neurosurgery. 136 (5): 1475–1484. doi: 10.3171/2021.5.JNS211033 . PMID   34653985.
  5. ↑ Robertson, F. C.; Wu, K. C.; Sha, R. M. (2022). "Stereotactic Neurosurgical Robotics With Real-Time Patient Tracking: A Cadaveric Study". Operative Neurosurgery. 22 (6): 425–432. doi:10.1227/ons.0000000000000155. hdl:1887/3570570. PMID   35867082.
  6. ↑ "510(k) Premarket Notification". U.S. Food and Drug Administration. 11 September 2023. Retrieved 13 June 2024.
  7. ↑ "510(k) Premarket Notification". U.S. Food and Drug Administration. 11 January 2024. Retrieved 13 June 2024.
  8. ↑ "Zeta Surgical secures first FDA clearance for robotic surgery system". Boston Business Journal. 11 September 2023. Retrieved 13 June 2024.
  9. ↑ "Zeta Surgical sees positive results in guided neurosurgery trial". Medical Device Network. 7 June 2024. Retrieved 13 June 2024.
  10. ↑ "Zeta Cranial Navigation System". iF Design Award. 2023. Retrieved 13 June 2024.
  11. ↑ "Zeta Surgical Neurosurgical Navigation System". Good Design Award. 2023. Retrieved 13 June 2024.
  12. ↑ "Zeta Surgical". Design + Industry. Retrieved 13 June 2024.
  13. ↑ AiThority (22 January 2024). "Zeta Surgical Appoints Professor James Choi as Focused Ultrasound Lead in Push for Incision-Less Brain Surgery". AiThority. Retrieved 13 June 2024.
  14. ↑ "State of the Field Report 2024: Chapter 8 - FUS Industry" (PDF). Focused Ultrasound Foundation. July 2024. Retrieved 13 June 2024.
  15. 1 2 "Emles Venture Partners" . Retrieved 13 June 2024.
  16. ↑ "Forbes 30 Under 30 List Spotlights 35 from MIT". MIT Alumni Association. 14 December 2023. Retrieved 13 June 2024.
  17. ↑ "Clinical and Scientific Advisors". CoaguloMed. Retrieved 13 June 2024.
  18. ↑ "Zeta Surgical comes out of stealth with a $5.2M raise for image-guided surgery". TechCrunch. 10 March 2022. Retrieved 13 June 2024.
  19. ↑ "White & Case Advises Zeta Surgical Inc. on Preferred Stock Financing". White & Case LLP. 5 March 2024. Retrieved 13 June 2024.
  20. ↑ "The Most Interesting Seniors in the Harvard Class of 2018". The Harvard Crimson. 21 June 2018. Retrieved 13 June 2024.


This page is based on this Wikipedia article
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.