Zinc finger protein 2

ZNF2
Identifiers
Aliases	ZNF2 , A1-5, ZNF661, Zfp661, zinc finger protein 2
External IDs	OMIM: 194500 MGI: 1919430 HomoloGene: 23275 GeneCards: ZNF2
Gene location (Human) Chr. Chromosome 2 (human) [1] Band 2q11.1 Start 95,165,432 bp [1] End 95,184,317 bp [1]
Gene location (Mouse) Chr. Chromosome 2 (mouse) [2] Band 2|2 F1 Start 127,416,582 bp [2] End 127,429,014 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in secondary oocyte endothelial cell pancreatic ductal cell stromal cell of endometrium islet of Langerhans ganglionic eminence tibialis anterior muscle smooth muscle tissue gastrocnemius muscle left adrenal gland Top expressed in spermatocyte urethra male urethra ganglionic eminence sternocleidomastoid muscle neural tube supraoptic nucleus superior frontal gyrus quadriceps femoris muscle seminiferous tubule More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding nucleic acid binding zinc ion binding DNA-binding transcription factor activity metal ion binding DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component nucleus intracellular anatomical structure Biological process regulation of transcription, DNA-templated transcription, DNA-templated regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 7549 72180 Ensembl ENSG00000275111 ENSMUSG00000034800 UniProt Q9BSG1 Q8BIQ3 RefSeq (mRNA) NM_021088 NM_001017396 NM_001282398 NM_001291604 NM_001291605 NM_001111029 NM_028141 NM_001355622 NM_001355623 RefSeq (protein) NP_001017396 NP_001269327 NP_001278533 NP_001278534 NP_066574 NP_001104499 NP_082417 NP_001342551 NP_001342552 Location (UCSC) Chr 2: 95.17 – 95.18 Mb Chr 2: 127.42 – 127.43 Mb PubMed search [3] [4]
Wikidata
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Zinc finger protein 2 is a protein that in humans is encoded by the ZNF2 gene. ^[5]

Function

The protein encoded by this gene belongs to the C2H2-type zinc-finger protein family. The exact function of this gene is not known, however, zinc-finger proteins are known to interact with DNA and function as transcription regulators. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

References

1. GRCh38: Ensembl release 89: ENSG00000275111 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000034800 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: Zinc finger protein 2" . Retrieved 2017-08-27.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.