Vibratory angioedema

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Vibratory angioedema
Specialty Dermatology

Vibratory angioedema is a form of physical urticaria that may be an inherited autosomal dominant trait, [1] or may be acquired after prolonged exposure to occupational vibration. [2] :155 [3]

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Cold urticaria Allergic reaction to low temperatures

Cold urticaria is a disorder where hives (urticaria) or large red welts form on the skin after exposure to a cold stimulus. The welts are usually itchy and often the hands and feet will become itchy and swollen as well. Hives vary in size from about 7mm in diameter to as big as about 27mm diameter or larger. This disorder, or perhaps two disorders with the same clinical manifestations, can be inherited or acquired. The acquired form is most likely to occur between ages 18–25, although it can occur as early as 5 years old in some cases. Life-threatening risks include suffocation resulting from pharyngeal angioedema induced by cold foods or beverages, drowning after shock from swimming in cold water and anaphylactic shock.

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Aquagenic pruritus is a skin condition characterized by the development of severe, intense, prickling-like epidermal itching without observable skin lesions and evoked by contact with water.

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Physical urticaria is a distinct subgroup of the urticaria that are induced by an exogenous physical stimulus rather than occurring spontaneously. There are seven subcategories that are recognized as independent diseases. Physical urticaria is known to be painful, itchy and physically unappealing; it can recur for months to years of a person's life.

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Cholinergic urticaria (CU) is a type of physical urticaria that appears when a person is sweating or their core body temperature increases.

Solar urticaria

Solar urticaria (SU) is a rare condition in which exposure to ultraviolet or UV radiation, or sometimes even visible light, induces a case of urticaria or hives that can appear in both covered and uncovered areas of the skin. It is classified as a type of physical urticaria. The classification of disease types is somewhat controversial. One classification system distinguished various types of SU based on the wavelength of the radiation that causes the breakout; another classification system is based on the type of allergen that initiates a breakout.

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Aquagenic urticaria, also known as water allergy and water urticaria, is a rare form of physical urticaria in which hives develop on the skin after contact with water, regardless of its temperature. It is sometimes described as an allergy, although it is not a true histamine-releasing allergic reaction like some other forms of urticaria. The condition typically results from contact with water of any type, temperature or additive.

Id reactions are types of acute dermatitis developing after days or weeks at skin locations distant from the initial inflammatory or infectious site. They can be localised or generalised. This is also known as an 'autoeczematous response' and there must be an identifiable initial inflammatory or infectious skin problem which leads to the generalised eczema. Often intensely itchy, the red papules and pustules can also be associated with blisters and scales and are always remote from the primary lesion. It is most commonly a blistering rash with itchy vesicles on the sides of fingers and feet as a reaction to fungal infection on the feet, athlete's foot. Stasis dermatitis, allergic contact dermatitis, acute irritant contact eczema and infective dermatitis have been documented as possible triggers, but the exact cause and mechanism is not fully understood. Several other types of id reactions exist including erythema nodosum, erythema multiforme, Sweet's syndrome and urticaria.

Drug-induced urticaria occurs by immunologic and nonimmunologic mechanisms, urticaria most commonly caused by aspirin and NSAIDs.

Adrenergic urticaria is a skin condition characterized by an eruption consisting of small (1-5mm) red macules and papules with a pale halo, appearing within 10 to 15 min after emotional upset. There have been 10 cases described in medical literature, and involve a trigger followed by a rise in catechomines and IgE. Treatment involves propranolol and trigger avoidance.

Heat urticaria presents within five minutes after the skin has been exposed to heat above 43 degrees Celsius, with the exposed area becoming burned, stinging, and turning red, swollen, and indurated.

Pressure urticaria is a physical urticaria caused by pressure applied to the skin, and is characterized by the development of swelling and pain that usually occurs 3 to 12 hours after local pressure has been applied.

Galvanic urticaria has been described after exposure to a galvanic (electrical) device used to treat hyperhidrosis.

Larva currens is an itchy, cutaneous condition caused by infections with Strongyloides stercoralis. It is caused by the intradermal migration of strongyloides and distinguished from cutaneous larva migrans by its rapid migration, perianal involvement and wide band of urticaria.

Contact stomatitis is characterized by cutaneous lesions that may be located where the offending agent contacts the mucosa for a prolonged time.

Urticarial allergic eruption is a cutaneous condition characterized by annular or gyrate urticarial plaques that persist for greater than 24 hours.

References

  1. Boyden SE, Desai A, Cruse G, Young ML, Bolan HC, Scott LM, et al. (February 2016). "Vibratory Urticaria Associated with a Missense Variant in ADGRE2". N. Engl. J. Med. 374 (7): 656–63. doi:10.1056/NEJMoa1500611. PMC   4782791 . PMID   26841242.
  2. James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN   0-7216-2921-0.
  3. Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. p. 267. ISBN   978-1-4160-2999-1.