Cranial neural crest

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Cranial neural crest
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Identifiers
Latin crista neuralis cranialis
TE E5.15.1.0.2.0.1
Anatomical terminology

The cranial neural crest is one of the four regions of the neural crest. [1]

The cranial neural crest arises in the anterior and populates the face and the pharyngeal arches giving rise to bones, cartilage, nerves and connective tissue. [2] The endocranium and facial bones of the skull are ultimately derived from crest cells.

Other Migration Locations:

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Mesoderm Middle germ layer that forms muscle, bone, blood vessels and more

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Neural crest cells are multipotent cells required for the development of cells, tissues and organ systems. A subpopulation of neural crest cells are the cardiac neural crest complex. This complex refers to the cells found amongst the midotic placode and somite 3 destined to undergo epithelial-mesenchymal transformation and migration to the heart via pharyngeal arches 3, 4 and 6.

The face and neck development of the human embryo refers to the development of the structures from the third to eighth week that give rise to the future head and neck. They consist of three layers, the ectoderm, mesoderm and endoderm, which form the mesenchyme, neural crest and neural placodes. The paraxial mesoderm forms structures named somites and somitomeres that contribute to the development of the floor of the brain and voluntary muscles of the craniofacial region. The lateral plate mesoderm consists of the laryngeal cartilages. The three tissue layers give rise to the pharyngeal apparatus, formed by six pairs of pharyngeal arches, a set of pharyngeal pouches and pharyngeal grooves, which are the most typical feature in development of the head and neck. The formation of each region of the face and neck is due to the migration of the neural crest cells which come from the ectoderm. These cells determine the future structure to develop in each pharyngeal arch. Eventually, they also form the neurectoderm, which forms the forebrain, midbrain and hindbrain, cartilage, bone, dentin, tendon, dermis, pia mater and arachnoid mater, sensory neurons, and glandular stroma.

Trabecular cartilage

Trabecular cartilages are paired, rod-shaped cartilages, which develop in the head of the vertebrate embryo. They are the primordia of the anterior part of the cranial base, and are derived from the cranial neural crest cells.

References

  1. "The Neural Crest" . Retrieved 2009-05-31.
  2. Grenier J, Teillet MA, Grifone R, Kelly RG, Duprez D (2009). Callaerts P (ed.). "Relationship between Neural Crest Cells and Cranial Mesoderm during Head Muscle Development". PLOS ONE. 4 (2): e4381. doi:10.1371/journal.pone.0004381. PMC   2634972 . PMID   19198652.
  3. Jiang HB, Tian WD, Liu LK, Xu Y (June 2008). "In vitro odontoblast-like cell differentiation of cranial neural crest cells induced by fibroblast growth factor 8 and dentin non-collagen proteins". Cell Biol. Int. 32 (6): 671–8. doi:10.1016/j.cellbi.2008.01.293. PMID   18339562. S2CID   5586748.
  4. Nie X, Zhang YJ, Tian WD, et al. (January 2007). "Improvement of peripheral nerve regeneration by a tissue-engineered nerve filled with ectomesenchymal stem cells". Int J Oral Maxillofac Surg. 36 (1): 32–8. doi:10.1016/j.ijom.2006.06.005. PMID   17169530.