10-Deacetylbaccatin

Last updated
10-Deacetylbaccatin III
Deacetylbaccatin.png
10-Deacetylbaccatin-III-3D-balls.png
Names
IUPAC name
(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(Acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,6,9,11-tetrahydroxy-4a,8,13,13-tetramethyl-7,11-methano-5H-cyclodeca(3,4)benz(1,2-b)oxet-5-one
Other names
10-Deacetylbaccatin III
10-Deacetylbaccatine III
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.128.614
PubChem CID
UNII
Properties
C29H36O10
Molar mass 544.59 g/mol
Appearancecolorless solid
Melting point 234 °C (453 °F; 507 K)
insoluble
Solubility soluble in methanol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

10-Deacetylbaccatins are a series of closely related natural organic compounds isolated from the yew tree (Genera Taxus ). 10-Deacetylbaccatin III is a precursor to the anti-cancer drug docetaxel (Taxotere).

10-deacetylbaccatin III 10-O-acetyltransferase converts 10-deacetylbaccatin to baccatin III:

acetyl-CoA + 10-deacetylbaccatin III CoA + baccatin III

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