Names | |
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IUPAC name (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(Acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,6,9,11-tetrahydroxy-4a,8,13,13-tetramethyl-7,11-methano-5H-cyclodeca(3,4)benz(1,2-b)oxet-5-one | |
Other names 10-Deacetylbaccatin III 10-Deacetylbaccatine III | |
Identifiers | |
3D model (JSmol) | |
ChEBI | |
ChEMBL | |
ChemSpider | |
ECHA InfoCard | 100.128.614 |
PubChem CID | |
UNII | |
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Properties | |
C29H36O10 | |
Molar mass | 544.59 g/mol |
Appearance | colorless solid |
Melting point | 234 °C (453 °F; 507 K) |
insoluble | |
Solubility | soluble in methanol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
Infobox references | |
10-Deacetylbaccatins are a series of closely related natural organic compounds isolated from the yew tree (Genera Taxus ). 10-Deacetylbaccatin III is a precursor to the anti-cancer drug docetaxel (Taxotere).
10-deacetylbaccatin III 10-O-acetyltransferase converts 10-deacetylbaccatin to baccatin III:
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Enoyl-CoA-(∆) isomerase, also known as dodecenoyl-CoA-(∆) isomerase, 3,2-trans-enoyl-CoA isomerase, ∆3(cis),∆2(trans)-enoyl-CoA isomerase, or acetylene-allene isomerase, is an enzyme that catalyzes the conversion of cis- or trans-double bonds of coenzyme A (CoA) bound fatty acids at gamma-carbon to trans double bonds at beta-carbon as below:
Dodecane (also known as dihexyl, bihexyl, adakane 12, or duodecane) is a liquid alkane hydrocarbon with the chemical formula CH3(CH2)10CH3 (or C12H26), an oily liquid of the paraffin series. It has 355 isomers.
Tiletamine is a dissociative anesthetic and pharmacologically classified as an NMDA receptor antagonist. It is related chemically to ketamine. Tiletamine hydrochloride exists as odorless white crystals.
Paclitaxel total synthesis in organic chemistry is a major ongoing research effort in the total synthesis of paclitaxel (Taxol). This diterpenoid is an important drug in the treatment of cancer but, also expensive because the compound is harvested from a scarce resource, namely the Pacific yew. Not only is the synthetic reproduction of the compound itself of great commercial and scientific importance, but it also opens the way to paclitaxel derivatives not found in nature but with greater potential.
Ciguatoxins are a class of toxic polycyclic polyethers found in fish that cause ciguatera.
2,4 Dienoyl-CoA reductase also known as DECR1 is an enzyme which in humans is encoded by the DECR1 gene which resides on chromosome 8. This enzyme catalyzes the following reactions
The crotonase family comprises mechanistically diverse proteins that share a conserved trimeric quaternary structure, the core of which consists of 4 turns of a (beta/beta/alpha)n superhelix.
Piperidinediones are a derivatives of piperidine with two ketone functional groups. There are six isomers, each of which has a molecular weight of 113.115 and a formula of C5H7NO2. Piperidinediones form the core structure of a variety of pharmaceutical drugs.
In enzymology, an isovaleryl-CoA dehydrogenase is an enzyme that catalyzes the chemical reaction
In enzymology, a long-chain-enoyl-CoA hydratase (EC 4.2.1.74) is an enzyme that catalyzes the chemical reaction
In enzymology, a 10-deacetylbaccatin III 10-O-acetyltransferase is an enzyme that catalyzes the chemical reaction
In enzymology, a beta-ketoacyl-acyl-carrier-protein synthase II (EC 2.3.1.179) is an enzyme that catalyzes the chemical reaction
Peroxisomal 3,2-trans-enoyl-CoA isomerase is an enzyme that in humans is encoded by the PECI gene.
Enoyl Coenzyme A hydratase, short chain, 1, mitochondrial, also known as ECHS1, is a human gene.
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial is an enzyme that in humans is encoded by the ECH1 gene.
Alkylpyrazines are chemical compounds based on pyrazine with different substitution patterns. Some alkylpyrazines are naturally occurring highly aromatic substances which often have a very low odor threshold and contribute to the taste and aroma of various foods including cocoa, baked goods, coffee and wines. Alkylpyrazines are also formed during the cooking of some foods via Maillard reactions.
Peroxisomal trans-2-enoyl-CoA reductase is an enzyme that in humans is encoded by the PECR gene.
1-Naphthyl isothiocyanate is a chemical compound which is an isothiocyanate derivative of naphthalene.
Baccatin III is an isolate from the yew tree. Baccatin III is a precursor to the anti-cancer drug paclitaxel (Taxol).