10-deacetylbaccatin III 10-O-acetyltransferase

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10-deacetylbaccatin III 10-O-acetyltransferase
Identifiers
EC no. 2.3.1.167
CAS no. 220946-63-4
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BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO
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NCBI proteins

In enzymology, a 10-deacetylbaccatin III 10-O-acetyltransferase (EC 2.3.1.167) is an enzyme that catalyzes the chemical reaction

acetyl-CoA + 10-deacetylbaccatin III CoA + baccatin III

Thus, the two substrates of this enzyme are acetyl-CoA and 10-deacetylbaccatin III, whereas its two products are CoA and baccatin III.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:taxan-10beta-ol O-acetyltransferase. This enzyme participates in diterpenoid biosynthesis.

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<span class="mw-page-title-main">Baccatin III</span> Chemical compound

Baccatin III is an isolate from the yew tree. Baccatin III is a precursor to the anti-cancer drug paclitaxel (Taxol).

References