List of EC numbers (EC 6)

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This list contains a list of EC numbers for the sixth group, EC 6, ligases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology. All official information is tabulated at the website of the committee. [1] The database is developed and maintained by Andrew McDonald. [2]

Contents

EC 6.1: Forming Carbon-Oxygen Bonds

EC 6.1.2: Acid—alcohol ligases (ester synthases)

* No Wikipedia article

EC 6.1.3: Cyclo-ligases

* No Wikipedia article

EC 6.2: Forming Carbon-Sulfur Bonds

EC 6.2.1: Acid-Thiol Ligases

+ EC 6.2.1.75: indoleacetate—CoA ligase

* No Wikipedia article

EC 6.2.2: Amide—thiol ligases

* No Wikipedia article

EC 6.3: Forming Carbon-Nitrogen Bonds

EC 6.3.1: Acid—Ammonia (or Amine) Ligases (Amide Synthases)

* No Wikipedia article

EC 6.3.2: Acid—Amino-Acid Ligases (Peptide Synthases)

* No Wikipedia article

EC 6.3.3: Cyclo-Ligases

* No Wikipedia article

EC 6.3.4: Other Carbon-Nitrogen Ligases

* No Wikipedia article

EC 6.3.5: Carbon-nitrogen ligases with glutamine as amido-N-donor

* No Wikipedia article

EC 6.4: Forming Carbon-Carbon Bonds

EC 6.4.1: Ligases that form carbon-carbon bonds (only sub-subclass identified to date)

*No Wikipedia article

EC 6.5: Forming Phosphoric Ester Bonds

EC 6.5.1: Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)

* No Wikipedia article

EC 6.6: Forming Nitrogen-Metal Bonds

EC 6.6.1: Forming Coordination Complexes

EC 6.7: Forming nitrogen-nitrogen bonds

EC 6.7.1: Forming diazo bonds

* No Wikipedia article

Related Research Articles

In enzymology, an adenosylcobyric acid synthase (glutamine-hydrolysing) (EC 6.3.5.10) is an enzyme that catalyzes the chemical reaction

In enzymology, an alanine—tRNA ligase is an enzyme that catalyzes the chemical reaction

In enzymology, an asparaginyl-tRNA synthase (glutamine-hydrolysing) is an enzyme that catalyzes the chemical reaction

Aspartate—tRNAAsn ligase is an enzyme with systematic name L-aspartate:tRNAAsx ligase (AMP-forming). This enzyme catalyses the following chemical reaction

In enzymology, a D-alanine—poly(phosphoribitol) ligase is an enzyme that catalyzes the chemical reaction

In enzymology, a glutaminyl-tRNA synthase (glutamine-hydrolysing) is an enzyme that catalyzes the chemical reaction

In enzymology, a hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing) (EC 6.3.5.9) is an enzyme that catalyzes the chemical reaction

In enzymology, a UDP-N-acetylmuramate—L-alanine ligase is an enzyme that catalyzes the chemical reaction

In enzymology, a UDP-N-acetylmuramoyl-L-alanine—D-glutamate ligase is an enzyme that catalyzes the chemical reaction

In enzymology, a UDP-N-acetylmuramoyl-L-alanyl-D-glutamate—L-lysine ligase is an enzyme that catalyzes the chemical reaction

In enzymology, a UDP-N-acetylmuramoyl-tripeptide—D-alanyl-D-alanine ligase is an enzyme that catalyzes the chemical reaction

In enzymology, an UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase (EC 2.3.2.10) is an enzyme that catalyzes the chemical reaction

The bacterial cell wall provides strength and rigidity to counteract internal osmotic pressure, and protection against the environment. The peptidoglycan layer gives the cell wall its strength, and helps maintain the overall shape of the cell. The basic peptidoglycan structure of both Gram-positive and Gram-negative bacteria comprises a sheet of glycan chains connected by short cross-linking polypeptides. Biosynthesis of peptidoglycan is a multi-step process comprising three main stages:

  1. formation of UDP-N-acetylmuramic acid (UDPMurNAc) from N-acetylglucosamine (GlcNAc).
  2. addition of a short polypeptide chain to the UDPMurNAc.
  3. addition of a second GlcNAc to the disaccharide-pentapeptide building block and transport of this unit through the cytoplasmic membrane and incorporation into the growing peptidoglycan layer.

N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-(N6-triglycine)-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine:glycine glycyltransferase (EC 2.3.2.18, femB (gene)) is an enzyme with systematic name N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-(N6-triglycine)-D-alanyl-D-alanine-ditrans,octacis-diphosphoundecaprenyl-N-acetylglucosamine:glycine glycyltransferase. This enzyme catalyses the following chemical reaction

Muramoylpentapeptide carboxypeptidase is an enzyme. This enzyme catalyses the following chemical reaction.

UDP-N-acetylmuramoyl-L-alanyl-D-glutamate—2,6-diaminopimelate ligase is an enzyme with systematic name UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:meso-2,6-diaminoheptanedioate gamma-ligase (ADP-forming). This enzyme catalyses the following chemical reaction

UDP-N-acetylmuramoyl-L-alanyl-D-glutamate—D-lysine ligase is an enzyme with systematic name UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:D-lysine alpha-ligase (ADP-forming). This enzyme catalyses the following chemical reaction

References

  1. "ExplorEnz – The Enzyme Database".
  2. McDonald, A.G.; Boyce, S.; K.F., Tipton (2009). "ExplorEnz: the primary source of the IUBMB enzyme list". Nucleic Acids Res. 37: D593–D597. doi:10.1093/nar/gkn582.