3-hydroxypropionyl-CoA synthase

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3-Hydroxypropionyl-CoA synthase
Identifiers
EC no. 6.2.1.36
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3-Hydroxypropionyl-CoA synthase (EC 6.2.1.36, 3-hydroxypropionyl-CoA synthetase (AMP-forming), 3-hydroxypropionate-CoA ligase) is an enzyme with systematic name hydroxypropionate:CoA ligase (AMP-forming). [1] [2] This enzyme catalyses the following chemical reaction

3-hydroxypropionate + ATP + CoA 3-hydroxypropionyl-CoA + AMP + diphosphate

This enzyme catalyses a step in the 3-hydroxypropionate/4-hydroxybutyrate cycle.

Related Research Articles

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References

  1. Berg IA, Kockelkorn D, Buckel W, Fuchs G (December 2007). "A 3-hydroxypropionate/4-hydroxybutyrate autotrophic carbon dioxide assimilation pathway in Archaea". Science. 318 (5857): 1782–6. doi:10.1126/science.1149976. PMID   18079405.
  2. Alber BE, Kung JW, Fuchs G (February 2008). "3-Hydroxypropionyl-coenzyme A synthetase from Metallosphaera sedula, an enzyme involved in autotrophic CO2 fixation". Journal of Bacteriology. 190 (4): 1383–9. doi:10.1128/JB.01593-07. PMC   2238213 . PMID   18165310.