Geranoyl-CoA carboxylase

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Geranoyl-CoA carboxylase
Identifiers
EC no. 6.4.1.5
CAS no. 37324-35-9
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BRENDA BRENDA entry
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KEGG KEGG entry
MetaCyc metabolic pathway
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In enzymology, a geranoyl-CoA carboxylase (EC 6.4.1.5) is an enzyme that catalyzes the chemical reaction

ATP + geranoyl-CoA + HCO3- ADP + phosphate + 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA

The 3 substrates of this enzyme are ATP, geranoyl-CoA, and HCO3-, whereas its 3 products are ADP, phosphate, and 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA.

This enzyme belongs to the family of ligases, specifically those forming carbon–carbon bonds. The systematic name of this enzyme class is geranoyl-CoA:carbon-dioxide ligase (ADP-forming). Other names in common use include geranoyl coenzyme A carboxylase, and geranyl-CoA carboxylase. It employs one cofactor, biotin.

Related Research Articles

Holocarboxylase synthetase ), also known as protein—biotin ligase, is a family of enzymes. This enzyme is important for the effective use of biotin, a B vitamin found in foods such as liver, egg yolks, and milk. In many of the body's tissues, holocarboxylase synthetase activates other specific enzymes by attaching biotin to them. These carboxylases are involved in many critical cellular functions, including the production and breakdown of proteins, fats, and carbohydrates.

<span class="mw-page-title-main">Phosphoenolpyruvate carboxylase</span> Class of enzymes

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<span class="mw-page-title-main">Acetate—CoA ligase (ADP-forming)</span> Class of enzymes

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<span class="mw-page-title-main">Biotin carboxylase</span> Class of enzymes

In enzymology, a biotin carboxylase (EC 6.3.4.14) is an enzyme that catalyzes the chemical reaction

In enzymology, a biotin-[methylcrotonoyl-CoA-carboxylase] ligase is an enzyme that catalyzes the chemical reaction

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<span class="mw-page-title-main">Phosphoribosylaminoimidazolesuccinocarboxamide synthase</span> Class of enzymes

In molecular biology, the protein domain SAICAR synthase is an enzyme which catalyses a reaction to create SAICAR. In enzymology, this enzyme is also known as phosphoribosylaminoimidazolesuccinocarboxamide synthase. It is an enzyme that catalyzes the chemical reaction

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The enzyme isohexenylglutaconyl-CoA hydratase (EC 4.2.1.57) catalyzes the chemical reaction

The enzyme [acetyl-CoA carboxylase]-phosphatase (EC 3.1.3.44) catalyzes the reaction

Adenosylcobinamide-phosphate synthase is an enzyme with systematic name adenosylcobyric acid:(R)-1-aminopropan-2-yl phosphate ligase (ADP-forming). This enzyme catalyses the following chemical reaction

Acetophenone carboxylase (EC 6.4.1.8) is an enzyme with systematic name acetophenone:carbon-dioxide ligase (ADP-forming). This enzyme catalyses the following chemical reaction

References


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