| Singles | |
|---|---|
| 2006 Western & Southern Financial Group Women's Open | |
| Champion |  Vera Zvonareva |
| Runner-up |  Katarina Srebotnik |
| Final score | 6–2, 6–4 |
| Draw | 32 |
| Seeds | 8 |
Patty Schnyder was the defending champion, but lost in semifinals to Katarina Srebotnik
Vera Zvonareva won the title, defeating Srebotnik 6–2, 6–4 in the final. It was the 2nd title of the year and the 5th on her career.
Patty Schnyder (semifinals) Anastasia Myskina (first round)
Katarina Srebotnik (final)
Jelena Janković (quarterfinals)
Marion Bartoli (quarterfinals) Tatiana Golovin (first round)
Gisela Dulko (second round)
Sania Mirza (quarterfinals)| Semifinals | Final | ||||||||||||
| 1 | Patty Schnyder | 6 | 3 | 66 | |||||||||
| 4 | Katarina Srebotnik | 4 | 6 | 78 | |||||||||
| 4 | Katarina Srebotnik | 2 | 4 | ||||||||||
| Vera Zvonareva | 6 | 6 | |||||||||||
| Vera Zvonareva | 6 | 6 | |||||||||||
 Serena Williams | 2 | 3 | |||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 1 | P Schnyder | 5 | 6 | 77 | |||||||||||||||||||||||
| L Osterloh | 7 | 2 | 61 | 1 | P Schnyder | 6 | 6 | ||||||||||||||||||||
| Q | A Spears | 6 | 5 | 6 | Q | A Spears | 1 | 0 | |||||||||||||||||||
| WC | A Glatch | 3 | 7 | 4 | 1 | P Schnyder | 79 | 7 | |||||||||||||||||||
 S Bammer | 3 | 1 | 9 | S Mirza | 67 | 5 | |||||||||||||||||||||
 E Laine | 6 | 6 | E Laine | 1 | 6 | 1 | |||||||||||||||||||||
| LL | A Stevenson | 1 | 0r | 9 | S Mirza | 6 | 0 | 6 | |||||||||||||||||||
| 9 | S Mirza | 6 | 2 | 1 | P Schnyder | 6 | 3 | 66 | |||||||||||||||||||
| 4 | K Srebotnik | 6 | 77 | 4 | K Srebotnik | 4 | 6 | 78 | |||||||||||||||||||
| Q |  R de los Ríos | 3 | 63 | 4 | K Srebotnik | 77 | 6 | ||||||||||||||||||||
 M Yuan | 6 | 7 | M Yuan | 63 | 1 | ||||||||||||||||||||||
| M Díaz Oliva | 3 | 5 | 4 | K Srebotnik | 6 | 6 | |||||||||||||||||||||
| Q | V Bardina | 63 | 6 | 6 | 6 | M Bartoli | 2 | 1 | |||||||||||||||||||
 H Šromová | 77 | 4 | 2 | Q | V Bardina | 2 | 6 | 3 | |||||||||||||||||||
| Q |  C-w Chan | 2 | 3 | 6 | M Bartoli | 6 | 2 | 6 | |||||||||||||||||||
| 6 | M Bartoli | 6 | 6 | ||||||||||||||||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 7 | T Golovin | 3 | 0 | ||||||||||||||||||||||||
| V Zvonareva | 6 | 6 | V Zvonareva | 6 | 6 | ||||||||||||||||||||||
 V Lepchenko | 4 | 6 | 6 | V Lepchenko | 0 | 2 | |||||||||||||||||||||
| LL |  N Grandin | 6 | 1 | 3 | V Zvonareva | 6 | 6 | ||||||||||||||||||||
| LL | C Gullickson | 1 | 1 | 5 | J Janković | 1 | 1 | ||||||||||||||||||||
 ME Camerin | 6 | 6 | ME Camerin | 4 | 4 | ||||||||||||||||||||||
 O Savchuk | 3 | 2 | 5 | J Janković | 6 | 6 | |||||||||||||||||||||
| 5 | J Janković | 6 | 6 | V Zvonareva | 6 | 6 | |||||||||||||||||||||
| 8 | G Dulko | 7 | 6 | S Williams | 2 | 3 | |||||||||||||||||||||
 M Domachowska | 5 | 3 | 8 | G Dulko | 3 | 1 | |||||||||||||||||||||
| WC | J Kirkland | 3 | 4 | A Frazier | 6 | 6 | |||||||||||||||||||||
| A Frazier | 6 | 6 | A Frazier | 2 | 2 | ||||||||||||||||||||||
| B Mattek | 3 | 6 | 6 | S Williams | 6 | 6 | |||||||||||||||||||||
| S Perry | 6 | 1 | 2 | B Mattek | 3 | 1 | |||||||||||||||||||||
| S Williams | 6 | 6 | S Williams | 6 | 6 | ||||||||||||||||||||||
| 2 | A Myskina | 2 | 2 | ||||||||||||||||||||||||
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