Seven teams contested in the 2010 AFC Champions League qualifying play-off. The two winners advanced to the 2010 AFC Champions League group stage. The losers entered the 2010 AFC Cup group stage.
| Round 1 | Final | ||||||||
| 1 | | 3 | |||||||
| 4 | | 0 | |||||||
| | 0 (4) | ||||||||
| | 0 (3) | ||||||||
| 3 | | 0 | |||||||
| 2 | | 3 | |||||||
| Round 1 | Final | ||||||||
| 1 | | 0 | |||||||
| 4 | | 1 | |||||||
| | 5 | ||||||||
| | 2 | ||||||||
| 3 | | ||||||||
| 2 | (bye) | - | |||||||
| SHB Đà Nẵng | 0 – 3 | |
|---|---|---|
| Report | Wongsa Kouakou Kaewprom |
| Al-Karamah | 0 – 1 | |
|---|---|---|
| Report | Khamees |