| 2020 Cary Challenger | |
|---|---|
| Date | 9–15 November |
| Edition | 6th |
| Surface | Hard |
| Location | Cary, United States |
| Champions | |
| Singles | |
 Denis Kudla | |
| Doubles | |
 Teymuraz Gabashvili / Dennis Novikov | |
The 2020 Cary Challenger was a professional tennis tournament played on hard courts. It was the 6th edition of the tournament which was part of the 2020 ATP Challenger Tour. It took place in Cary, North Carolina, United States between 9 and 15 November 2020.
| Country | Player | Rank1 | Seed |
|---|---|---|---|
 BRA | Thiago Monteiro | 80 | 1 |
| USA | Denis Kudla | 122 | 2 |
 COL | Daniel Elahi Galán | 131 | 3 |
 IND | Prajnesh Gunneswaran | 146 | 4 |
 EGY | Mohamed Safwat | 155 | 5 |
| USA | Michael Mmoh | 172 | 6 |
 KAZ | Dmitry Popko | 173 | 7 |
| USA | Mackenzie McDonald | 191 | 8 |
The following players received wildcards into the singles main draw:
The following players received entry from the qualifying draw:
Denis Kudla def. Prajnesh Gunneswaran 3–6, 6–3, 6–0. Teymuraz Gabashvili / Dennis Novikov def. 
Luke Bambridge / Nathaniel Lammons 7–5, 4–6, [10–8].