ARL6IP1

ARL6IP1
Identifiers
Aliases	ARL6IP1 , AIP1, ARL6IP, ARMER, SPG61, ADP ribosylation factor like GTPase 6 interacting protein 1
External IDs	OMIM: 607669 MGI: 1858943 HomoloGene: 41008 GeneCards: ARL6IP1
Gene location (Human)
Chr.	Chromosome 16 (human)
End	18,801,572 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	117,728,885 bp
RNA expression pattern
	Top expressed in
	retinal pigment epithelium; ; superior frontal gyrus; ; embryo; ; ganglionic eminence; ; postcentral gyrus; ; pons; ; Brodmann area 9; ; orbitofrontal cortex; ; prefrontal cortex; ; superior vestibular nucleus;
	Top expressed in
	retinal pigment epithelium; ; spermatocyte; ; yolk sac; ; ciliary body; ; kidney; ; median eminence; ; thymus; ; dorsomedial hypothalamic nucleus; ; neural tube; ; proximal tubule;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding ; identical protein binding ;
Cellular component	cytoplasm ; cytosol ; membrane ; Sec61 translocon complex ; endoplasmic reticulum ; endomembrane system ; endoplasmic reticulum membrane ; integral component of endoplasmic reticulum membrane ; integral component of membrane ;
Biological process	cotranslational protein targeting to membrane ; endoplasmic reticulum tubular network formation ; apoptotic process ; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process ; endoplasmic reticulum tubular network membrane organization ; negative regulation of apoptotic process ; positive regulation of L-glutamate import across plasma membrane ;
	Sources:Amigo / QuickGO
Orthologs
	23204
	54208
	ENSG00000170540
	ENSMUSG00000030654
	Q15041
	Q9JKW0
	NM_015161 ; NM_001313858
	NM_019419
	NP_001300787 ; NP_055976
	NP_062292
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated August 19, 2023

ADP-ribosylation factor-like protein 6-interacting protein 1 is a protein that in humans is encoded by the ARL6IP1 gene.^[5]

Related Research Articles

ADP-ribosylation factor 6 (ARF6) is a member of the ADP ribosylation factor family of GTP-binding proteins. ARF6 has a variety of cellular functions that are frequently involved in trafficking of biological membranes and transmembrane protein cargo. ARF6 has specifically been implicated in endocytosis of plasma membrane proteins and also, to a lesser extent, plasma membrane protein recycling.

ADP-ribosylation factor 1 is a protein that in humans is encoded by the ARF1 gene.

Cytohesin-2 is a protein that in humans is encoded by the CYTH2 gene.

PRA1 family protein 3 is a protein that in humans is encoded by the ARL6IP5 gene.

ADP-ribosylation factor 5 is a protein that in humans is encoded by the ARF5 gene.

ADP-ribosylation factor-like protein 4A is a protein that in humans is encoded by the ARL4A gene.

ADP-ribosylation factor-like protein 3 is a protein that in humans is encoded by the ARL3 gene.

ADP-ribosylation factor-like protein 1 is a protein that in humans is encoded by the ARL1 gene.

Tubulin-specific chaperone D is a protein that in humans is encoded by the TBCD gene.

ADP-ribosylation factor-like protein 2 is a protein that in humans is encoded by the ARL2 gene.

ADP-ribosylation factor-like protein 6 is a protein that in humans is encoded by the ARL6 gene.

ADP-ribosylation factor-related protein 1 is a protein that in humans is encoded by the ARFRP1 gene.

ADP-ribosylation factor-like protein 4D is a protein that in humans is encoded by the ARL4D gene.

Cytohesin-3 is a protein that in humans is encoded by the CYTH3 gene.

Arfaptin-2 is a protein that in humans is encoded by the ARFIP2 gene.

ADP-ribosylation factor-like protein 11 is a protein that in humans is encoded by the ARL11 gene.

ADP-ribosylation factor-like protein 8A is a protein that in humans is encoded by the ARL8A gene.

ADP-ribosylation factor-like protein 13B (ARL13B), also known as ADP-ribosylation factor-like protein 2-like 1, is a protein that in humans is encoded by the ARL13B gene.

ADP-ribosylation-like factor 6 interacting protein 4 (ARL6IP4), also called SRp25 is the product of the ARL6IP4 gene located on chromosome 12q24. 31. Its function is unknown.

ADP ribosylation factor like GTPase 6 interacting protein 6 is a protein that in the humans is encoded by the ARL6IP6 gene. It spans from 152,717,893 to 152,761,253 on the plus strand.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000170540 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000030654 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1".

External links

Human ARL6IP1 genome location and ARL6IP1 gene details page in the UCSC Genome Browser .

Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
Lui HM, Chen J, Wang L, Naumovski L (2003). "ARMER, apoptotic regulator in the membrane of the endoplasmic reticulum, a novel inhibitor of apoptosis". Mol. Cancer Res. 1 (7): 508–18. PMID 12754298.
Pettersson M, Bessonova M, Gu HF, Groop LC, Jönsson JI (2000). "Characterization, chromosomal localization, and expression during hematopoietic differentiation of the gene encoding Arl6ip, ADP-ribosylation-like factor-6 interacting protein (ARL6)". Genomics. 68 (3): 351–4. doi:10.1006/geno.2000.6278. PMID 10995579.
Ingley E, Williams JH, Walker CE, Tsai S, Colley S, Sayer MS, Tilbrook PA, Sarna M, Beaumont JG, Klinken SP (1999). "A novel ADP-ribosylation like factor (ARL-6), interacts with the protein-conducting channel SEC61beta subunit". FEBS Lett. 459 (1): 69–74. doi:10.1016/S0014-5793(99)01188-6. PMID 10508919. S2CID 30948975.
Nomura N, Nagase T, Miyajima N, Sazuka T, Tanaka A, Sato S, Seki N, Kawarabayasi Y, Ishikawa K, Tabata S (1994). "Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1". DNA Res. 1 (5): 223–9. doi: 10.1093/dnares/1.5.223 . PMID 7584044.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000170540 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000030654 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1".

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ARL6IP1

Contents

Related Research Articles

References

External links

Further reading