ARL6IP1

ARL6IP1
Identifiers
Aliases	ARL6IP1 , AIP1, ARL6IP, ARMER, SPG61, ADP ribosylation factor like GTPase 6 interacting protein 1
External IDs	OMIM: 607669; MGI: 1858943; HomoloGene: 41008; GeneCards: ARL6IP1; OMA:ARL6IP1 - orthologs
Gene location (Human) Chr. Chromosome 16 (human) [1] Band 16p12.3 Start 18,791,669 bp [1] End 18,801,572 bp [1]
Gene location (Mouse) Chr. Chromosome 7 (mouse) [2] Band 7|7 F1 Start 117,718,114 bp [2] End 117,728,885 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in retinal pigment epithelium ventricular zone superior frontal gyrus embryo ganglionic eminence postcentral gyrus pons Brodmann area 9 orbitofrontal cortex prefrontal cortex Top expressed in retinal pigment epithelium Epithelium of choroid plexus spermatocyte neural layer of retina right kidney yolk sac choroid plexus of fourth ventricle ciliary body fetal liver hematopoietic progenitor cell human kidney More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding identical protein binding Cellular component cytoplasm cytosol membrane Sec61 endoplasmic reticulum endomembrane system endoplasmic reticulum membrane integral component of endoplasmic reticulum membrane integral component of membrane Biological process cotranslational protein targeting to membrane endoplasmic reticulum tubular network formation apoptotic process negative regulation of cysteine-type endopeptidase activity involved in apoptotic process endoplasmic reticulum tubular network membrane organization negative regulation of apoptotic process positive regulation of L-glutamate import across plasma membrane Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 23204 54208 Ensembl ENSG00000170540 ENSMUSG00000030654 UniProt Q15041 Q9JKW0 RefSeq (mRNA) NM_015161 NM_001313858 NM_019419 RefSeq (protein) NP_001300787 NP_055976 NP_062292 Location (UCSC) Chr 16: 18.79 – 18.8 Mb Chr 7: 117.72 – 117.73 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

ADP-ribosylation factor-like protein 6-interacting protein 1 is a protein that in humans is encoded by the ARL6IP1 gene. ^[5]

References

1. GRCh38: Ensembl release 89: ENSG00000170540 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000030654 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1".

External links

• Human ARL6IP1 genome location and ARL6IP1 gene details page in the UCSC Genome Browser .

Further reading

• Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID   16189514. S2CID   4427026.
• Lui HM, Chen J, Wang L, Naumovski L (2003). "ARMER, apoptotic regulator in the membrane of the endoplasmic reticulum, a novel inhibitor of apoptosis". Mol. Cancer Res. 1 (7): 508–18. PMID   12754298.
• Pettersson M, Bessonova M, Gu HF, Groop LC, Jönsson JI (2000). "Characterization, chromosomal localization, and expression during hematopoietic differentiation of the gene encoding Arl6ip, ADP-ribosylation-like factor-6 interacting protein (ARL6)". Genomics. 68 (3): 351–4. doi:10.1006/geno.2000.6278. PMID   10995579.
• Ingley E, Williams JH, Walker CE, Tsai S, Colley S, Sayer MS, Tilbrook PA, Sarna M, Beaumont JG, Klinken SP (1999). "A novel ADP-ribosylation like factor (ARL-6), interacts with the protein-conducting channel SEC61beta subunit". FEBS Lett. 459 (1): 69–74. doi:10.1016/S0014-5793(99)01188-6. PMID   10508919. S2CID   30948975.
• Nomura N, Nagase T, Miyajima N, Sazuka T, Tanaka A, Sato S, Seki N, Kawarabayasi Y, Ishikawa K, Tabata S (1994). "Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1". DNA Res. 1 (5): 223–9. doi: 10.1093/dnares/1.5.223 . PMID   7584044.