ARMC6

ARMC6
Identifiers
Aliases	ARMC6 , R30923_1, armadillo repeat containing 6
External IDs	MGI: 1924063; HomoloGene: 14121; GeneCards: ARMC6; OMA:ARMC6 - orthologs
Gene location (Human) Chr. Chromosome 19 (human) [1] Band 19p13.11 Start 19,033,575 bp [1] End 19,060,311 bp [1]
Gene location (Mouse) Chr. Chromosome 8 (mouse) [2] Band 8|8 B3.3 Start 70,672,822 bp [2] End 70,687,116 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right lobe of liver gonad apex of heart ganglionic eminence granulocyte mucosa of transverse colon right lobe of thyroid gland prefrontal cortex left testis right testis Top expressed in barrel cortex dentate gyrus of hippocampal formation granule cell superior cervical ganglion visual cortex otic vesicle neural tube superior frontal gyrus primary visual cortex spinal ganglia lumbar spinal ganglion More reference expression data BioGPS More reference expression data
Orthologs Species Human Mouse Entrez 93436 76813 Ensembl ENSG00000105676 ENSMUSG00000002343 UniProt Q6NXE6 Q8BNU0 RefSeq (mRNA) NM_001199196 NM_033415 NM_133972 RefSeq (protein) NP_001186125 NP_219483 NP_598733 Location (UCSC) Chr 19: 19.03 – 19.06 Mb Chr 8: 70.67 – 70.69 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

The human gene ARMC6 encodes a protein called Armadillo repeat-containing protein 6. ^{[5] [6]}

The function of this gene's protein product has not been determined. A related protein in mouse suggests that this protein has a conserved function. ^[6]

The protein is characterized by the presence of armadillo repeats in its amino acid sequence. Diseases associated with ARMC6 include pancreatic cancer, and pancreatitis.

References

1. GRCh38: Ensembl release 89: ENSG00000105676 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000002343 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, et al. (Dec 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc Natl Acad Sci U S A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
6. "Entrez Gene: ARMC6 armadillo repeat containing 6".

External links

• Human ARMC6 genome location and ARMC6 gene details page in the UCSC Genome Browser .

Further reading

• Grimwood J, Gordon LA, Olsen A, Terry A, Schmutz J, Lamerdin J, et al. (2004). "The DNA sequence and biology of human chromosome 19" (PDF). Nature. 428 (6982): 529–35. Bibcode:2004Natur.428..529G. doi: 10.1038/nature02399 . PMID   15057824.
• Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC   1847948 . PMID   17353931.