ASCC2

ASCC2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2DI0
Identifiers
Aliases	ASCC2 , ASC1p100, p100, activating signal cointegrator 1 complex subunit 2
External IDs	OMIM: 614216; MGI: 1922702; HomoloGene: 41774; GeneCards: ASCC2; OMA:ASCC2 - orthologs
Gene location (Human) Chr. Chromosome 22 (human) [1] Band 22q12.2 Start 29,788,609 bp [1] End 29,838,304 bp [1]
Gene location (Mouse) Chr. Chromosome 11 (mouse) [2] Band 11|11 A1 Start 4,587,747 bp [2] End 4,635,699 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in granulocyte blood minor salivary glands right lobe of thyroid gland right lobe of liver left lobe of thyroid gland mucosa of transverse colon body of stomach left adrenal cortex right adrenal gland Top expressed in Paneth cell ciliary body yolk sac urothelium transitional epithelium of urinary bladder internal carotid artery external carotid artery cumulus cell lens retinal pigment epithelium More reference expression data BioGPS More reference expression data
Orthologs Species Human Mouse Entrez 84164 75452 Ensembl ENSG00000100325 ENSMUSG00000020412 UniProt Q9H1I8 Q91WR3 RefSeq (mRNA) NM_001242906 NM_032204 NM_029291 NM_001376980 RefSeq (protein) NP_001229835 NP_115580 NP_001356849 NP_001356850 NP_001356851 NP_001356852 NP_001356853 NP_001356854 NP_001356855 NP_001356856 NP_001356857 NP_001356858 NP_001356859 NP_001356860 NP_001356861 NP_001356862 NP_001356863 NP_001356864 NP_001356865 NP_001356866 NP_001356867 NP_001356868 NP_001356869 NP_001356870 NP_001356871 NP_001356872 NP_001356873 NP_001356874 NP_001356875 NP_001356876 NP_001356877 NP_001356878 NP_001356879 NP_083567 NP_001363909 Location (UCSC) Chr 22: 29.79 – 29.84 Mb Chr 11: 4.59 – 4.64 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Activating signal cointegrator 1 complex subunit 2 is a protein that in humans is encoded by the ASCC2 gene. ^{[5] [6] [7]}

References

1. GRCh38: Ensembl release 89: ENSG00000100325 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000020412 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Jung DJ, Sung HS, Goo YW, Lee HM, Park OK, Jung SY, Lim J, Kim HJ, Lee SK, Kim TS, Lee JW, Lee YC (2002). "Novel transcription coactivator complex containing activating signal cointegrator 1". Mol. Cell. Biol. 22 (14): 5203–11. doi:10.1128/MCB.22.14.5203-5211.2002. PMC   139772 . PMID   12077347.
6. Sanger Centre, The; Washington University Genome Sequencing Cente, The (1998). "Toward a complete human genome sequence". Genome Res. 8 (11): 1097–108. doi: 10.1101/gr.8.11.1097 . PMID   9847074.
7. "Entrez Gene: ASCC2 activating signal cointegrator 1 complex subunit 2".

External links

• Human ASCC2 genome location and ASCC2 gene details page in the UCSC Genome Browser .
• Overview of all the structural information available in the PDB for UniProt : Q9H1I8 (Activating signal cointegrator 1 complex subunit 2) at the PDBe-KB .

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID   8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID   9373149.
• Dunham I, Shimizu N, Roe BA, Chissoe S, Hunt AR, Collins JE, Bruskiewich R, Beare DM, Clamp M, Smink LJ, Ainscough R, Almeida JP, Babbage A, Bagguley C, Bailey J, Barlow K, Bates KN, Beasley O, Bird CP, Blakey S, Bridgeman AM, Buck D, Burgess J, Burrill WD, O'Brien KP (1999). "The DNA sequence of human chromosome 22". Nature. 402 (6761): 489–95. Bibcode:1999Natur.402..489D. doi: 10.1038/990031 . PMID   10591208.
• Colland F, Jacq X, Trouplin V, Mougin C, Groizeleau C, Hamburger A, Meil A, Wojcik J, Legrain P, Gauthier JM (2004). "Functional proteomics mapping of a human signaling pathway". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC   442148 . PMID   15231748.
• Carroll JS, Liu XS, Brodsky AS, Li W, Meyer CA, Szary AJ, Eeckhoute J, Shao W, Hestermann EV, Geistlinger TR, Fox EA, Silver PA, Brown M (2005). "Chromosome-wide mapping of estrogen receptor binding reveals long-range regulation requiring the forkhead protein FoxA1". Cell. 122 (1): 33–43. doi: 10.1016/j.cell.2005.05.008 . PMID   16009131.
• Stelzl U, Worm U, Lalowski M, Haenig C, Brembeck FH, Goehler H, Stroedicke M, Zenkner M, Schoenherr A, Koeppen S, Timm J, Mintzlaff S, Abraham C, Bock N, Kietzmann S, Goedde A, Toksöz E, Droege A, Krobitsch S, Korn B, Birchmeier W, Lehrach H, Wanker EE (2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957–68. doi:10.1016/j.cell.2005.08.029. hdl: 11858/00-001M-0000-0010-8592-0 . PMID   16169070. S2CID   8235923.