ASZ1

ASZ1
Identifiers
Aliases	ASZ1 , ALP1, ANKL1, C7orf7, CT1.19, GASZ, Orf3, ankyrin repeat, SAM and basic leucine zipper domain containing 1
External IDs	OMIM: 605797; MGI: 1921318; HomoloGene: 11374; GeneCards: ASZ1; OMA:ASZ1 - orthologs
Gene location (Human) Chr. Chromosome 7 (human) [1] Band 7q31.2 Start 117,363,222 bp [1] End 117,428,123 bp [1]
Gene location (Mouse) Chr. Chromosome 6 (mouse) [2] Band 6|6 A2 Start 18,050,963 bp [2] End 18,109,060 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle gonad right testis left testis buccal mucosa cell corpus callosum sperm stromal cell of endometrium lower lobe of lung granulocyte Top expressed in spermatocyte primary oocyte zygote secondary oocyte spermatid seminiferous tubule Gonadal ridge left lung lobe morula urethra More reference expression data BioGPS More reference expression data
Gene ontology Molecular function signal transducer activity Cellular component cytoplasm pi-body Biological process male meiotic nuclear division multicellular organism development cell differentiation meiosis spermatogenesis DNA methylation involved in gamete generation gene silencing signal transduction piRNA metabolic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 136991 74068 Ensembl ENSG00000154438 ENSMUSG00000010796 UniProt Q8WWH4 Q49AP3 Q8VD46 RefSeq (mRNA) NM_001301821 NM_001301822 NM_130768 NM_023729 RefSeq (protein) NP_001288750 NP_001288751 NP_570124 NP_076218 Location (UCSC) Chr 7: 117.36 – 117.43 Mb Chr 6: 18.05 – 18.11 Mb PubMed search [3] [4]
Wikidata
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Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 is a protein that in humans is encoded by the ASZ1 gene. ^{[5] [6] [7]}

References

1. GRCh38: Ensembl release 89: ENSG00000154438 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000010796 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Yan W, Rajkovic A, Viveiros MM, Burns KH, Eppig JJ, Matzuk MM (May 2002). "Identification of Gasz, an evolutionarily conserved gene expressed exclusively in germ cells and encoding a protein with four ankyrin repeats, a sterile-alpha motif, and a basic leucine zipper". Mol Endocrinol. 16 (6): 1168–84. doi: 10.1210/mend.16.6.0864 . PMID   12040005.
6. Zenklusen JC, Conti CJ, Green ED (Mar 2001). "Mutational and functional analyses reveal that ST7 is a highly conserved tumor-suppressor gene on human chromosome 7q31". Nat Genet. 27 (4): 392–8. doi:10.1038/86891. PMID   11279520. S2CID   2749283.
7. "Entrez Gene: ASZ1 ankyrin repeat, SAM and basic leucine zipper domain containing 1".

External links

• Human ASZ1 genome location and ASZ1 gene details page in the UCSC Genome Browser .

Further reading

• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Zink D, Amaral MD, Englmann A, et al. (2004). "Transcription-dependent spatial arrangements of CFTR and adjacent genes in human cell nuclei". J. Cell Biol. 166 (6): 815–25. doi:10.1083/jcb.200404107. PMC   2172106 . PMID   15364959.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology". Science. 300 (5620): 767–72. Bibcode:2003Sci...300..767S. doi:10.1126/science.1083423. PMC   2882961 . PMID   12690205.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.