Akhilesh Pandey

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Akhilesh Pandey
Nationality Indian American
Alma mater
Scientific career
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Institutions

Akhilesh Pandey is an Indian-American proteomicist and a Professor at Department of Laboratory Medicine and Pathology, Center for Individualized Medicine of Mayo Clinic in Rochester, Minnesota, USA. [1] [2] [3] He is also the founding director and chief scientific advisor of the Institute of Bioinformatics in Bangalore, India. [4]

Contents

Education

Pandey earned his medical degree from Armed Forces Medical College in Pune and completed his pathology residency at Brigham and Women's Hospital, Harvard Medical School in Boston, Massachusetts. He received his Ph.D. in Molecular Biology from the University of Michigan in Ann Arbor, Michigan, USA. He was a Postdoctoral Fellow in Harvey Lodish's laboratory at the Whitehead Institute for Biomedical Research at the Massachusetts Institute of Technology in Cambridge, Massachusetts. He was a Visiting Scientist in Matthias Mann's group at the University of Southern Denmark. [5] [6]

Career

For 16 years, he was a Professor at the Johns Hopkins University School of Medicine's McKusick-Nathans Institute of Genetic Medicine and the Departments of Biological Chemistry, Oncology, and Pathology. In 2002, he founded the Institute of Bioinformatics (IOB) in Bangalore, India. [7] [8]

IOB's work on a virtually complete protein map of humans was featured on the cover of the Nature's volume in May 2014, with the title "The Human Proteome." [9] [10] The DST of the Government of India published "India's Research Landscape: Output, Collaboration, and Comparative Performance - Bibliometric Studies" on February 17, 2016, which contained two reports. The first study, "India's Research Output and Collaboration (2005–2014): A Bibliometric Study," was put together by Thomson Reuters, and the second, "International Comparative Performance of India's Research Base (2009–2014)," was put together independently by Elsevier. In the field of biology and biochemistry, the 2009 paper "Human Protein Reference Database" was ranked second among the top 10 publications with Indian affiliation, and the 2014 Nature cover article "A draft map of human proteome" was ranked sixth after receiving more than 400 citations in a short period of time. [11]

Awards and honours

Pandey has the Human Proteome Organization(HUPO)'s Discovery in Proteomic Sciences Award. The Wellcome Trust/DBT India Alliance named him a Margdarshi Fellow, and he established a Center for Molecular Medicine at NIMHANS in Bangalore as a result. He is an Associate Editor of Clinical Proteomics and a member of the Editorial Boards of Molecular and Cellular Proteomics, Proteomics, and the Journal of Clinical Investigation . He has received the Howard Temin Award from the National Cancer Institute, the Experimental Pathologist-In-Training Award from the American Society for Investigative Pathology, and the Sidney Kimmel Scholar Award from the Sidney Kimmel Foundation for Cancer Research. The United States Department of Defense also bestowed upon him the Era of Hope Scholar Award. [12]

Related Research Articles

<span class="mw-page-title-main">Proteomics</span> Large-scale study of proteins

Proteomics is the large-scale study of proteins. Proteins are vital parts of living organisms, with many functions such as the formation of structural fibers of muscle tissue, enzymatic digestion of food, or synthesis and replication of DNA. In addition, other kinds of proteins include antibodies that protect an organism from infection, and hormones that send important signals throughout the body.

<span class="mw-page-title-main">Max Planck Institute of Biochemistry</span> Research institute in Martinsried, Germany

The Max Planck Institute of Biochemistry is a research institute of the Max Planck Society located in Martinsried, a suburb of Munich. The institute was founded in 1973 by the merger of three formerly independent institutes: the Max Planck Institute of Biochemistry, the Max Planck Institute of Protein and Leather Research, and the Max Planck Institute of Cell Chemistry.

The Human Protein Reference Database (HPRD) is a protein database accessible through the Internet. It is closely associated with the premier Indian Non-Profit research organisation Institute of Bioinformatics (IOB), Bangalore, India. This database is a collaborative output of IOB and the Pandey Lab of Johns Hopkins University.

<span class="mw-page-title-main">National Institute of Mental Health and Neurosciences</span> Mental hospital in Bangalore, India

The National Institute of Mental Health and Neuro-Sciences is a medical institution in Bangalore, India. NIMHANS is the apex centre for mental health and neuroscience education in the country. It is an Institute of National Importance operating autonomously under the Ministry of Health and Family Welfare. NIMHANS is ranked 4th best medical institute in India, in the current National Institutional Ranking Framework.

<span class="mw-page-title-main">NetPath</span>

NetPath is a manually curated resource of human signal transduction pathways. It is a joint effort between Pandey Lab at the Johns Hopkins University and the Institute of Bioinformatics (IOB), Bangalore, India, and is also worked on by other parties.

Human Proteinpedia, which is closely associated with Institute of Bioinformatics (IOB), Bangalore and Johns Hopkins University, is a portal for sharing and integration of human proteomic data. It allows research laboratories to contribute and maintain protein annotations. Human Protein Reference Database (HPRD) integrates data, that is deposited in Human Proteinpedia along with the existing literature curated information at the context of an individual protein. In essence, researchers can add new data to HPRD by registering to Human Proteinpedia. The data deposited in Human Proteinpedia is freely available for download. Emphasizing the importance of proteomics data disposition to public repositories, Nature Methods recommends Human Proteinpedia in their editorial. More than 70 labs participate in this effort.

BIOBASE is an international bioinformatics company headquartered in Wolfenbüttel, Germany. The company focuses on the generation, maintenance, and licensing of databases in the field of molecular biology, and their related software platforms.

Marc R. Wilkins is an Australian scientist who is credited with the defining the concept of the proteome. Wilkins is a Professor in the School of Biotechnology and Biomolecular Sciences at the University of New South Wales, Sydney.

Samir Kumar Brahmachari is an Indian biophysicist and Former Director General of the Council of Scientific & Industrial Research (CSIR) and Former Secretary, Department of Scientific and Industrial Research (DSIR), Government of India. He is the Founder Director of Institute of Genomics and Integrative Biology (IGIB), New Delhi and the Chief Mentor of Open Source for Drug Discovery (OSDD) Project. He is the recipient of J.C Bose Fellowship Award, DST (2012). In addition, he is one of the featured researchers in the India Cancer Research Database developed by Institute of Bioinformatics (IOB), Bangalore with support from the Department of Biotechnology, Government of India.

<span class="mw-page-title-main">M. R. S. Rao</span> Indian scientist (1948–2023)

Manchanahalli Rangaswamy Satyanarayana Rao was an Indian scientist. He was awarded the fourth-highest civilian award, the Padma Shri, for Science and Engineering in 2010. From 2003 to 2013 he was president of Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR) in Bangalore, India.

<span class="mw-page-title-main">Rolf Apweiler</span>

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Ralph H. Hruban is professor of pathology and oncology at the Johns Hopkins School of Medicine. He is currently Director of the Sol Goldman Pancreatic Cancer Research Center at Johns Hopkins, and Baxley Professor and Director of the Department of Pathology. He is a world expert on pancreatic cancer.

David Fenyö is a Hungarian-Swedish-American computational biologist, physicist and businessman. He is currently professor in the Department of Biochemistry and Molecular Pharmacology at NYU Langone Medical Center. Fenyö's research focuses on the development of methods to identify, characterize and quantify proteins and in the integration of data from multiple modalities including mass spectrometry, sequencing and microscopy.

Debasis Dash is an Indian computational biologist and chief scientist at the Institute of Genomics and Integrative Biology (IGIB). Known for his research on proteomics and Big Data and Artificial Intelligence studies, his studies have been documented by way of a number of articles and ResearchGate, an online repository of scientific articles has listed 120 of them. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to biosciences, in 2014. He was appointed as the director of Institute of Life Sciences, Bhubaneswar on 18 May 2023.

<span class="mw-page-title-main">Ganesan Venkatasubramanian</span> Indian psychiatrist and clinician

Ganesan Venkatasubramanian is an Indian psychiatrist and clinician-scientist who works as a professor of psychiatry at the National Institute of Mental Health and Neurosciences, Bangalore (NIMHANS). His overarching research interest to learn the science that will facilitate a personalized approach to understand and treat severe mental disorders like schizophrenia. Venkatasubramanian is known for his studies in the fields of schizophrenia, transcranial Direct Current Stimulation (tDCS), brain imaging, neuroimmunology, neurometabolism and several other areas of biological psychiatry. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, for his contributions to medical sciences in 2018. He was also one of the collaborating scientists in the NIMHANS-IOB Bioinformatics and Proteomics laboratory of the Institute of Bioinformatics (IOB) in Bangalore and NIMHANS. Besides, he is an adjunct faculty at the Centre for Brain Research (CBR) in Bangalore.

Catherine E. Costello is the William Fairfield Warren distinguished professor in the department of biochemistry, Cell Biology and Genomics, and the director of the Center for Biomedical Mass Spectrometry at the Boston University School of Medicine.

Kathryn S Lilley is a professor of biochemistry at the University of Cambridge, director of the Cambridge Center for Proteomics, and an elected member of the European Molecular Biology Organization (EMBO).

The Institute of Bioinformatics, often referred to as IOB, is an Indian not-for-profit academic research organization based in Bangalore, India. It is involved in research in the fields of bioinformatics, multi-omics, systems biology and neurological disorders. In 2002, the institute was set up by The Genomics Research Trust and the Johns Hopkins University of Baltimore, Maryland. This organization is recognized as a 'Scientific and Industrial Research Organization' (SIRO) of the Department of Scientific and Industrial Research, Government of India. Renowned Proteomicist Akhilesh Pandey, Professor at Department of Laboratory Medicine and Pathology, Center for Individualized Medicine of Mayo Clinic in Rochester, Minnesota, USA is the Founding and current Director of IOB, and eminent Proteomicist Ravi Sirdeshmukh, Founder President of the 'Proteomic Society of India' is the current Associate Director of IOB.

Ravi Sirdeshmukh is an Indian cancer biologist and proteomicist. He is a distinguished scientist and incumbent associate director of the Institute of Bioinformatics (IOB) in Bangalore, founding president of the Proteomics Society of India and senior research advisor at the Mazumdar Shaw Center for Translational Research (MSCTR) in Bangalore. He is also an elected member of the Council of Human Proteome Organization. He is most noted for his contributions in the Human Proteome Project where he served as the Group Leader for the countries like India, Singapore, Taiwan and Thailand. Sirdeshmukh is also an invited member of the Council of Asian Oceanean HUPO (AOHUPO).

Prof. Susarla Krishna Shankar was a neuropathologist and neuroscientist who served as a Director of National Institute of Mental Health and Neuro Sciences (NIMHANS), Bengaluru, India. He also served as a Professor and Head of the Department of Neuropathology of NIMHANS from 1998 to 2012. He served in NIMHANS for more than three decades. He founded the first and only Brain Bank in India at NIMHANS to encourage neuroscience research in the nation. He, a former Research Associate in the AIIMS, New Delhi, was regarded as a pioneer in the field of biobanking. He was honored with the Pioneer in Biobanking Award by the Biobank of India Federation and is regarded as the 'Father of brain banking in India'. He also served as the President of the Neuropathology Society of India. He founded the Neuropathology Brain Museum, which is first of its kind in India, housed in NIMHANS. In addition, he was a consultant for the Bioinformatics and Proteomics Laboratory of the Institute of Bioinformatics (IOB) housed in NIMHANS. He was involved in the collaborative project of 'Human Proteome Map' of Institute of Bioinformatics (IOB), NIMHANS and Johns Hopkins University. He had been an elected fellow of various prestigious academic bodies like the College of Pathologists, the National Academy of Medical Sciences and the National Academy of Sciences.

References

  1. ↑ "Akhilesh Pandey, MD, PhD".
  2. ↑ "Akhilesh Pandey Mayo Clinic".
  3. ↑ "Akhilesh Pandey H-index and Awards".
  4. ↑ "Dr. Akhilesh Pandey Founder and Director of Institute of Bioinformatics".
  5. ↑ "Akhilesh Pandey, M.D., Ph.D."
  6. ↑ "Dr. Akhilesh Pandey, Founder and Director, Institute of Bioinformatics".
  7. ↑ Rohatgi, Ritu (22 April 2003). "Unravelling life". Times of India.
  8. ↑ "Akhilesh Pandey, M.D., Ph.D." Science Cafe in Japan. 22 April 2003.
  9. ↑ "Nature (Volume 509 Issue 7502, 29 May 2014)".
  10. ↑ "NDTV coverage on the Human Proteome Map".
  11. ↑ "India's Research Output and Collaboration (2005-14): A Bibliometric Study (Phase II)" (PDF). Thomson Reuters. 2017.
  12. ↑ "Akhilesh Pandey MD, PhD, Biochemistry and Molecular Genetics, Baltimore, Maryland, United States of America". eMedEvents. 2017.
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