Al Aynsley-Green

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Anand, K.J.S.; Sippell, W.G.; Aynsley-Green, A. (January 1987). "Randomised Trial of Fentanyl Anaesthesia in Preterm Babies Undergoing Surgery: Effects on the Stress Response". The Lancet. 329 (8524): 62–66. doi:10.1016/S0140-6736(87)91907-6. PMID   2879174. S2CID   21766926.
  • Bitner-Glindzicz, Maria; Lindley, Keith J.; Rutland, Paul; et al. (September 2000). "A recessive contiguous gene deletion causing infantile hyperinsulinism, enteropathy and deafness identifies the Usher type 1C gene". Nature Genetics. 26 (1): 56–60. doi:10.1038/79178. PMID   10973248. S2CID   2237489.
  • Cornblath, M.; Hawdon, J. M.; Williams, A. F.; Aynsley-Green, A.; Ward-Platt, M. P.; Schwartz, R.; Kalhan, S. C. (1 May 2000). "Controversies Regarding Definition of Neonatal Hypoglycemia: Suggested Operational Thresholds". Pediatrics. 105 (5): 1141–1145. doi:10.1542/peds.105.5.1141. PMID   10790476.
  • Dunne, Mark J.; Cosgrove, Karen E.; Shepherd, Ruth M.; Aynsley-Green, Albert; Lindley, Keith J. (January 2004). "Hyperinsulinism in Infancy: From Basic Science to Clinical Disease". Physiological Reviews. 84 (1): 239–275. doi:10.1152/physrev.00022.2003. PMID   14715916. S2CID   2538093.
  • Bitner-Glindzicz, Maria; Lindley, Keith J.; Rutland, Paul; Blaydon, Diana; Smith, Virpi V.; Milla, Peter J.; Hussain, Khalid; Furth-Lavi, Judith; Cosgrove, Karen E.; Shepherd, Ruth M.; Barnes, Philippa D.; O'Brien, Rachel E.; Farndon, Peter A.; Sowden, Jane; Liu, Xue-Zhong; Scanlan, Matthew J.; Malcolm, Sue; Dunne, Mark J.; Aynsley-Green, Albert; Glaser, Benjamin (September 2000). "A recessive contiguous gene deletion causing infantile hyperinsulinism, enteropathy and deafness identifies the Usher type 1C gene". Nature Genetics. 26 (1): 56–60. doi:10.1038/79178. PMID   10973248. S2CID   2237489.
  • Clayton, Peter T.; Eaton, Simon; Aynsley-Green, Albert; Edginton, Mark; Hussain, Khalid; Krywawych, Steve; Datta, Vipan; Malingré, Helga E.M.; Berger, Ruud; van den Berg, Inge E.T. (1 August 2001). "Hyperinsulinism in short-chain L-3-hydroxyacyl-CoA dehydrogenase deficiency reveals the importance of β-oxidation in insulin secretion". Journal of Clinical Investigation. 108 (3): 457–465. doi:10.1172/jci200111294. PMC   209352 . PMID   11489939.
  • Dunne, Mark J.; Kane, Charlotte; Shepherd, Ruth M.; Sanchez, Jorge A.; James, Roger F.L.; Johnson, Paul R.V.; Aynsley-Green, Albert; Lu, Shan; Clement, John P.; Lindley, Keith J.; Seino, Susumu; Aguilar-Bryan, Lydia; Gonzalez, Gabriela; Milla, Peter J. (6 March 1997). "Familial Persistent Hyperinsulinemic Hypoglycemia of Infancy and Mutations in the Sulfonylurea Receptor". New England Journal of Medicine. 336 (10): 703–706. doi:10.1056/NEJM199703063361005. hdl: 2381/35991 . PMID   9041101.
  • Cornblath, Marvin; Schwartz, Robert; Aynsley-Green, Albert; Lloyd, June K. (May 1990). "Hypoglycemia in Infancy: The Need for a Rational Definition". Pediatrics. 85 (5): 834–837. doi:10.1542/peds.85.5.834. ISSN   0031-4005. S2CID   7172574.
  • The following are books that Aynsley-Green wrote or co-wrote:

    The following are proceedings that Aynsley-Green wrote or co-wrote:

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    References

    1. 1 2 "A champion for children: Sir Al Aynsley-Green". British Medical Association. 30 June 2016. Retrieved 26 October 2018.
    2. 1 2 3 "Professor Sir Albert Aynsley Green". RCPCH. Retrieved 2 September 2018.
    3. 1 2 "Professor Sir Albert Aynsley Green Kt". www.aynsley-green.com. Archived from the original on 3 September 2018. Retrieved 2 September 2018.
    4. Aynsley-Green, A. (2006). Bullying Today (PDF) (Report). London: Office of the Children's Commissioner. Retrieved 2 September 2018.
    5. "Aynsley-Green, Sir Albert, (born 30 May 1943), Founder and Director, Aynsley-Green Consulting, since 2010; Children's Commissioner for England, 2005–10; Nuffield Professor of Child Health, Institute of Child Health, University College London, 1993–2005, now Emeritus; President, British Medical Association, 2015–16". Aynsley-Green, Sir Albert. A & C Black, an imprint of Bloomsbury. 2007. doi:10.1093/ww/9780199540884.013.U6070. ISBN   978-0-19-954088-4 . Retrieved 3 November 2018.{{cite book}}: |website= ignored (help)
    6. 1 2 3 4 5 6 "Sir Al Aynsley-Green". The Conversation. Profile: The Conversation Trust. 22 October 2018. Retrieved 26 October 2018.
    7. 1 2 Aynsley-Green, Albert (2007). "Reflections on Children, Child Health and Society" (PDF). Nuffield Trust. Queen Elizabeth The Queen Mother Fellowship Lecture. p. 6. Retrieved 26 October 2018.
    8. 1 2 Aynsley-Green, A.; Barker, Maggie; Morgan, John; Turner, Tom; Waterston, Tony (22 July 2000). "Who is speaking for children and adolescents and for their health at the policy level?". BMJ. 321 (7255): 229–232. doi:10.1136/bmj.321.7255.229. PMC   1118224 . PMID   10903661.
    9. The Lancet (August 2001). "Time to be serious about children's health care". The Lancet. 358 (9280): 431. doi:10.1016/S0140-6736(01)05606-9. S2CID   2874279.
    10. Health, Department of. "National Clinical Directors". National Archives. Email message: UK Government. Archived from the original on 5 January 2012. Retrieved 4 November 2018.
    11. "Yesterday in Parliament". Telegraph Media Group. The Telegraph. 19 July 2001. Retrieved 10 November 2018.
    12. Butler, Patrick (3 August 2001). "Call to establish children's commissioner". Guardian News and Media Limited. The Guardian. Retrieved 3 November 2018.
    13. "National service framework: children, young people and maternity services" (pdf). United Kingdom Government. UK Gov. 4 October 2004. Retrieved 10 November 2018.
    14. "England kids' champion appointed". CBBC. NewsRound. 2 March 2005. Retrieved 9 November 2018.
    15. 1 2 Wardrop, Murray (3 February 2010). "'Britain is one of world's most unfriendly countries towards children'". Telegraph Media Group. The Telegraph. Retrieved 9 November 2018.
    16. 1 2 Wilby, Peter. "Children's champion". Guardian News and Media Limited. The Guardian. Retrieved 10 November 2018.
    17. "Sir Al Aynsley-Green". The Conversation. The Conversation Trust (UK) Limited. 22 October 2018. Retrieved 10 November 2018.
    18. 1 2 "A champion for children: Sir Al Aynsley-Green". British Medical Association. BMA. 26 February 2018. Retrieved 9 November 2018.
    19. Vevers, Vevers (2 May 2007). "Impact of Al Aynsley-Green as children's commissioner questioned". Community Care group. MA Education. Retrieved 10 November 2018.
    20. 1 2 "UK Children's Commissioners' Report to the UN Committee on the Rights of the Child" (PDF). Children’s Commissioner for Wales. June 2008. Retrieved 9 November 2018.
    21. Hollins, Sheila; Porter, Mark; Chand, Kailash; Hajioff, Steve; Dearden, Andrew; Mansfield, Averil; Dangerfield, Peter; Datta, Shreelata; Davis, Lucy-Jane; Harding, Louise; Maguire, Peter; Moorthy, Ram; Rees, Michael; Steadman, Philip; Thomson, Andrew; De Souza, Beryl (May 2013). Growing up in the UK - BMA (pdf). British Medical Association: BMA Board of Science. p. ix. ISBN   978-0-9575831-0-8 . Retrieved 4 November 2018.
    22. Kennedy, Ian (16 September 2010). "Getting it right for children and young people: Overcoming cultural barriers in the NHS so as to meet their needs" (pdf). UK Government. Department of Health. Retrieved 4 November 2018.
    23. "Sir Al Aynsley-Green appointed". Church of England. Diocese of Salisbury. 17 November 2010. Archived from the original on 26 October 2018. Retrieved 26 October 2018.
    24. "AYNSLEY-GREEN, Albert, Sir". Companies House. Retrieved 26 October 2018.
    25. "Previous Winners". European Society for Paediatric Endocrinology. ESPE. 1991. Retrieved 2 November 2018.
    26. Stewart, William (23 June 2006). "Head knighted for double act". Times Educational Supplement . Retrieved 2 September 2018.
    27. "Honorary Fellows". Oriel College Oxford. University of Oxford. 6 January 2016. Retrieved 26 October 2018.
    28. "Honorary graduates". Nottingham Trent University Alumni. Nottingham: Nottingham Trent University. 2011. Retrieved 2 November 2018.
    29. Ferguson, Donna (23 October 2018). "Britain has created a crisis in childhood, says former children's commissioner". Guardian News and Media Limited. The Guardian . Retrieved 3 November 2018.
    Sir
    Albert Aynsley-Green
    Children's Commissioner for England
    In office
    2005–2009