Amersham plc

Last updated

Amersham plc
FormerlyThe Radiochemical Centre at Amersham
The Radiochemical Centre Ltd
Amersham International plc
Type Private
Industry Health care
Founded1946;76 years ago (1946)
Defunct2003;19 years ago (2003)
FateAcquired by GE Healthcare
Headquarters,

Amersham plc was a manufacturer of radiopharmaceutical products, to be used in diagnostic and therapeutic nuclear medicine procedures. The company became GE Healthcare following a takeover in 2003, which was based at the original site in Amersham, Buckinghamshire until 2016, when the headquarters moved to Chicago. [1]

Contents

History

Chilcote House in Little Chalfont near Amersham was first used for extraction of radium from radium concentrates in 1940, under Walter Patrick Grove. Over the next four years over 500 kilograms of radium bromide was produced, to be used to make luminous dials and instruments. [2] In 1946 the facility was taken over by the Ministry of Supply and it became known as the “national centre for the processing and distribution of radium, radon and artificial radioactive substances for scientific, medical and industrial purposes”. [3] With a new focus on healthcare and industrial applications, the site was expanded and by 1949 when the name changed to "The Radiochemical Centre (TRC), Amersham", production included radium gas capsules for cancer treatment and carbon-14. The following year it became an outstation of the Atomic Energy Research Establishment (UKAERA) at Harwell, processing materials produced in its reactors. [2] [4]

By the 1960s, TRC had over 1000 catalogue items, using over 100 isotopes and exporting to 60 countries. A cyclotron was installed, the first for medical isotope production. [3] With restructuring of the UKAERA in 1971, TRC became a limited company. [5] By this time TRC had several international subsidiaries for example Amersham Buchler GmbH & Co. KG a Joint Venture with the Quinine Factory Buchler GmbH in Braunschweig (West-Germany). In 1976 work began on a second production site in Cardiff.

The Radiochemical Centre Limited became Amersham International Limited in 1981 and was the first company to be privatised by the Thatcher Government [2] in 1982 under the new name Amersham International plc. [4] It was the first privatisation in which the government sold 100% of its shares in a company. The offer was 24.6 times subscribed, meaning the share price rose from 142p per share to 188p per share by closing on the first day. [6] The government retained a special share, allowing the veto of any outsourcing attempts, until it was redeemed in 1988.

In the early 1990s, the in-vitro diagnostic assay business was divested to a joint venture with Eastman Kodak called Amerlite Diagnostics Ltd, this was later wholly acquired by Eastman Kodak and renamed Kodak Clinical Diagnostics Ltd. This business was sold by Kodak to Johnson & Johnson and became known as Johnson & Johnson Clinical Diagnostics Ltd. The business is now called Ortho-Clinical Diagnostics Ltd.

In 1997 Pharmacia Biotech (Sweden), then owned by Pharmacia & Upjohn, was fused with Amersham Life Science and renamed Amersham Pharmacia Biotech. [7] The Pharmacia name of this subsidiary was later dropped when Pharmacia & Upjohn sold its share of the company to Amersham plc, and changed its name to Amersham Biosciences in 2001.

In 1997, Amersham merged with Nycomed (Norway) [7] to form Nycomed Amersham plc. In 1999, the Nycomed Pharma subsidiary was sold to Nordic Capital, [8] and in 2001 Nycomed Amersham plc was renamed to Amersham plc. [9]

In 2004, Amersham was acquired by the American firm General Electric (GE) and incorporated into the GE Healthcare business segment. [10]

In 2005 the Royal Society of Chemistry named the former Amersham Laboratories, known as the Grove Centre under GE, as an historic chemical landmark for its "achievements in the fields of industrial and medical applications" over the past six decades. [11] [12]

Operations

GE Healthcare has a UK office in Chalfont St. Giles, near Amersham.

In 2018 part of the company's 30- acre (12  ha ) Cardiff site was sold for redevelopment as operations consolidated into a smaller area. [13]

Amersham's former business segments became GE Healthcare Medical Diagnostics and GE Healthcare Life Sciences. In 2020 GE Healthcare Life Sciences was acquired by Danaher Corporation and renamed Cytiva. [14]

See also

Related Research Articles

Pharmacia Pharmaceutical and biotechnological company

Pharmacia was a pharmaceutical and biotechnological company in Sweden that merged with the American pharmaceutical company Upjohn in 1995.

Amersham Human settlement in England

Amersham is a market town and civil parish within the unitary authority of Buckinghamshire, England, in the Chiltern Hills, 27 miles (43 km) northwest of central London, 15 miles (24 km) from Aylesbury and 9 miles (14 km) from High Wycombe. Amersham is part of the London commuter belt.

Little Chalfont Human settlement in England

Little Chalfont is a village and civil parish in south-east Buckinghamshire, England. It is one of a group of villages known collectively as The Chalfonts, which also comprises Chalfont St Giles and Chalfont St Peter. Little Chalfont is located around 2 miles (3.2 km) east of Amersham and 21.9 miles (35.2 km) northwest of Charing Cross, central London.

GE Healthcare is a subsidiary of American multinational conglomerate General Electric incorporated in New York and headquartered in Chicago, Illinois. As of 2017, it is a manufacturer and distributor of diagnostic imaging agents and radiopharmaceuticals for imaging modalities used in medical imaging procedures. It offers dyes used in magnetic-resonance-imaging procedures; manufactures medical diagnostic equipment, including CT image machines; and develops Health technology for medical imaging and information technologies, medical diagnostics, patient monitoring systems, disease research, drug discovery, and biopharmaceutical manufacturing. It was incorporated in 1994 and operates in more than 100 countries.

Pharmacia & Upjohn

Pharmacia & Upjohn was a global pharmaceutical company formed by the merger of Sweden-based Pharmacia AB and the American company Upjohn in 1995. Today the remainder of the company is owned by Pfizer. In 1997, Pharmacia & Upjohn sold several brands to Johnson & Johnson, including Motrin and Cortaid.

Tolbutamide Chemical compound

Tolbutamide is a first-generation potassium channel blocker, sulfonylurea oral hypoglycemic medication. This drug may be used in the management of type 2 diabetes if diet alone is not effective. Tolbutamide stimulates the secretion of insulin by the pancreas.

Fresenius SE & Co. KGaA is a health care company based in Bad Homburg vor der Höhe, Germany. It provides products and services for dialysis, in hospitals and inpatient and outpatient medical care. It is involved in hospital management and in engineering and services for medical centers and other health care facilities.

Biacore was a life science products company based in Sweden. In June 2006 Biacore was sold for $390 million and became a product brand under GE Healthcare life Sciences, which became Cytiva in April 2020.

Hikma Pharmaceuticals plc is a British multinational pharmaceutical company with headquarters in London, UK that manufactures non-branded generic and in-licensed pharmaceutical products. It was founded by Samih Darwazah in Amman, Jordan in 1978. It is listed on the London Stock Exchange and is a constituent of the FTSE 100 Index.

Fred Hassan, is a Pakistan-born American business executive who works for Warburg Pincus and was CEO of three global pharmaceutical companies.

Ioflupane (<sup>123</sup>I) Chemical compound

Ioflupane (123I) is the international nonproprietary name (INN) of a cocaine analogue which is a neuro-imaging radiopharmaceutical drug, used in nuclear medicine for the diagnosis of Parkinson's disease and the differential diagnosis of Parkinson's disease over other disorders presenting similar symptoms. During the DaT scan procedure it is injected into a patient and viewed with a gamma camera in order to acquire SPECT images of the brain with particular respect to the striatum, a subcortical region of the basal ganglia. The drug is sold under the brand name Datscan and is manufactured by GE Healthcare, formerly Amersham plc.

Whatman plc is a Cytiva brand specialising in laboratory filtration products and separation technologies.

SeHCAT Chemical compound

SeHCAT is a drug used in a clinical test to diagnose bile acid malabsorption.

Nycomed Swiss pharmaceutical company

Nycomed is a Swiss pharmaceutical company. Nycomed was acquired by Takeda Pharmaceuticals in September 2011. Production was located in Norway, Denmark, Poland, Austria, Belgium, Germany, Estonia, India, Mexico, Brazil and Argentina. Head office is located in Zürich, Switzerland. Total revenue was €3,400 million in 2006 and the group had 12,000 employees then. The company awarded an annual prize totaling 20,000 euros to four excellent junior scientists at the University of Konstanz. Also, the award promoted the concept of scientific exchange and networking of its winners.

EKF Diagnostics

EKF Diagnostics is a publicly listed Healthcare company founded 1990 in Barleben, Germany and currently headquartered in Cardiff, Wales, UK.

Stefano Buono Italian physicist

Stefano Buono is an Italian physicist, Chief Executive Officer and member of the board of directors of Advanced Accelerator Applications, a company he founded in 2002 to develop a patent from the European Organization for Nuclear Research (CERN) in the radioisotope production field.

Viatris Inc. is an American global healthcare company headquartered in Canonsburg, Pennsylvania. The company was formed through the merger of Mylan and Upjohn, a division of Pfizer, on November 16, 2020.

References

  1. Ray, Justin (11 January 2016). "GE Healthcare Moving Global Headquarters to Chicago". NBC Chicago.
  2. 1 2 3 Clutterbuck, John. "Amersham's Modern Alchemists". Amersham Museum. Retrieved 6 November 2018.
  3. 1 2 Kitson, Sean L. (August 2007). "Amersham radiochemistry to GE Healthcare". Journal of Labelled Compounds and Radiopharmaceuticals. 50 (9–10): 737–745. doi:10.1002/jlcr.1427.
  4. 1 2 "The findings of NII's assessment of Amersham plc's 'site' periodic safety review". HM Nuclear Installations Inspectorate. April 2002. Retrieved 12 June 2009.{{cite journal}}: Cite journal requires |journal= (help)
  5. Walter C. Patterson (1985). Going Critical: An Unofficial History of British Nuclear Power (PDF). Paladin. ISBN   0-586-08516-5 . Retrieved 12 June 2009.
  6. "House of Commons Library Research Paper" (PDF). 2014.
  7. 1 2 "Amersham plc – Our Heritage". Archived from the original on 2 February 2004. Retrieved 2 February 2004.
  8. "Nycomed sells pharma unit to Nordic Capital - May 5, 1999". money.cnn.com. Retrieved 13 April 2021.
  9. "Nycomed Amersham changes name to Amersham PLC". AuntMinnie.com. Retrieved 13 April 2021.
  10. "General Electric buys Amersham". BBC. 10 October 2003. Retrieved 12 June 2009.
  11. "The Royal Society of Chemistry names the Grove Centre an historic chemical landmark" (Press release). Royal Society of Chemistry. 17 February 2005.
  12. Warschauer, Judy (16 March 2005). "Landmark award for Grove Centre". Bucks Free Press.
  13. Barry, Sion (28 May 2018). "Huge GE Healthcare site in Cardiff acquired in a £18m deal". walesonline.
  14. Hargreaves, Ben (1 April 2020). "GE Healthcare Life Sciences completes transition into Cytiva". BioPharma-Reporter.