F. Hoffmann-La Roche AG, commonly known as Roche, is a Swiss multinational holding healthcare company that operates worldwide under two divisions: Pharmaceuticals and Diagnostics. Its holding company, Roche Holding AG, has shares listed on the SIX Swiss Exchange. The company headquarters are located in Basel. Roche is the fifth-largest pharmaceutical company in the world by revenue and the leading provider of cancer treatments globally. In 2023, the company’s seat in Forbes Global 2000 was 76.
Arthur Mitchell Sackler was an American psychiatrist and marketer of pharmaceuticals whose fortune originated in medical advertising and trade publications. He was also an art collector. He was one of the three patriarchs of the controversial Sackler family pharmaceutical dynasty.
C.H. Boehringer Sohn AG & Co. KG is the parent company of the Boehringer Ingelheim group, which was founded in 1885 by Albert Boehringer (1861–1939) in Ingelheim am Rhein, Germany. As of 2018, Boehringer Ingelheim is one of the world's largest pharmaceutical companies, and the largest private one. Headquartered in Ingelheim, it operates globally with 146 affiliates and more than 47,700 employees. Unlike most large pharmaceutical companies which are listed, the company is private and fully owned by the Boehringer, Liebrecht and von Baumbach families. The company's key areas of interest are: respiratory diseases, metabolism, immunology, oncology and diseases of the central nervous system. Boehringer Ingelheim is a full member of the European Federation of Pharmaceutical Industries and Associations (EFPIA). The corporate logo of Boehringer Ingelheim depicts a stylized rendition of the central section of the imperial palace of Charlemagne.
Sackler is a surname. Notable people with the surname include:
Endo International plc is an American Irish-domiciled generics and specialty branded pharmaceutical company that generated over 93% of its 2017 sales from the U.S. healthcare system. While Endo's management, operations, and customers are almost exclusively U.S.–based, in 2013 Endo executed a corporate tax inversion to Ireland to avoid U.S. corporate taxes on their U.S. drug sales, and to avail of Ireland's corporate tax system.
Purdue Pharma L.P., formerly the Purdue Frederick Company (1892–2019), was an American privately held pharmaceutical company founded by John Purdue Gray. It was sold to Arthur, Mortimer, and Raymond Sackler in 1952, and then owned principally by the Sackler family and their descendants.
Raymond Sackler was an American physician and businessman. He acquired Purdue Pharma together with his brothers Arthur M. Sackler and Mortimer Sackler. Purdue Pharma is the developer of OxyContin, the drug at the center of the opioid epidemic in the United States.
Mortimer David Sackler was an American-born psychiatrist and entrepreneur who was a co-owner, with his brothers Arthur and Raymond, of Purdue Pharma. During his lifetime, Sackler's philanthropy included donations to the Metropolitan Museum of Art, the Tate Gallery, the Royal College of Art, the Louvre and Berlin's Jewish Museum.
Elizabeth Ann Sackler is a public historian, arts activist, and the daughter of Arthur M. Sackler and descendant of the Sackler family. She is the founder of the American Indian Ritual Object Repatriation Foundation and the Elizabeth A. Sackler Center for Feminist Art at the Brooklyn Museum.
Richard Stephen Sackler is an American businessman and physician who was the chairman and president of Purdue Pharma, a former company best known as the developer of OxyContin, whose initiation of the opioid epidemic in the United States became the subject of many lawsuits and fines, filing for bankruptcy in 2019. The company's downfall was the subject of the 2021 Hulu miniseries Dopesick and the 2023 Netflix miniseries Painkiller, in which Sackler is portrayed by Michael Stuhlbarg and Matthew Broderick, respectively.
Massachusetts v. Purdue is a lawsuit filed on August 14, 2018, suing the Stamford, Connecticut-based company Purdue Pharma LP, which created and manufactures OxyContin, "one of the most widely used and prescribed opioid drugs on the market", and Purdue's owners, the Sacklers accusing them of "widespread fraud and deception in the marketing of opioids, and contributing to the opioid crisis, the nationwide epidemic that has killed thousands." Purdue denied the allegations.
The Sackler family is an American family who owned the pharmaceutical company Purdue Pharma and later founded Mundipharma. Purdue Pharma, and some members of the family, have faced lawsuits regarding overprescription of addictive pharmaceutical drugs, including OxyContin. Purdue Pharma has been criticized for its role in the opioid epidemic in the United States. They have been described as the "most evil family in America", and "the worst drug dealers in history".
Napp Pharmaceuticals Limited is a private pharmaceutical company in Cambridge, United Kingdom that was founded in 1923 and bought by the Sackler family in 1966. Headquartered together with the related Napp Research Centre in the Cambridge Science Park since the 1980s, it is a sister company of Purdue Pharma and Mundipharma, all of which are owned by the descendants of Mortimer and Raymond Sackler.
The timeline of the opioid epidemic includes selected events related to the origins of Stamford, Connecticut-based Purdue Pharma, the Sackler family, the development and marketing of oxycodone, selected FDA activities related to the abuse and misuse of opioids, the recognition of the opioid epidemic, the social impact of the crisis, lawsuits against Purdue and the Sackler family.
Empire of Pain: The Secret History of the Sackler Dynasty is a 2021 book by Patrick Radden Keefe. The book examines the history of the Sackler family, including the founding of Purdue Pharma, its role in the marketing of pharmaceuticals, and the family's central role in the opioid epidemic. The book followed Keefe's 2017 article on the Sackler family in The New Yorker, titled "The Family That Built an Empire of Pain".
The Crime of the Century is an American two-part documentary film directed, produced, and written by Alex Gibney. The film follows the opioid epidemic in the United States, and the political operatives, government regulations and corporations that enable the abuse of opioids, particularly the Sackler family and Purdue Pharma.
Joss Sackler is a fashion designer. She is also known for her marriage to David Sackler, whose father Richard Sackler was the chairman and president of Purdue Pharma, and oversaw its manufacturing of the highly addictive opioid Oxycontin, a leading drug in the opioid epidemic.
Curtis Wright IV is an American former government official known for his role in the Food and Drug Administration's approval of OxyContin for Purdue Pharma in 1995, followed by his subsequent employment by the company, which led to portrayals in films and reports in nonfiction books, magazines, and news media outlets of his alleged role as one of the key figures in the current opioid epidemic in the United States. Wright was implicated in a criminal conspiracy outlined in a 2006 United States Department of Justice review document that was first made public in Purdue Pharma's 2019 bankruptcy proceedings. Although that case was settled in a 2007 plea agreement deal, members of United States Congress have requested the full 2006 documentation from the Department of Justice with the goal of opening a new case based upon the evidence then gathered. Parts of Wright's sworn depositions in 2003 and 2018 have internal contradictions and differ from documentary evidence described the 2003–2006 U.S. Federal Government investigation into Purdue Pharma.
Painkiller is an American drama television miniseries created by Micah Fitzerman-Blue and Noah Harpster. Based on Patrick Radden Keefe's New Yorker article "The Family That Built an Empire of Pain" and Pain Killer: An Empire of Deceit and the Origin of America's Opioid Epidemic by Barry Meier, the series focuses on the birth of the opioid crisis, with an emphasis on Purdue Pharma, the company owned by Richard Sackler and his family that was the manufacturer of OxyContin. The Sackler family has been described as the "most evil family in America", and "the worst drug dealers in history".
Harrington v. Purdue Pharma L.P., 603 U.S. ___ (2024), is a United States Supreme Court case regarding Chapter 11 of the Bankruptcy Code. This case is about the settlement by Purdue Pharma for opioid victims who overdosed with the OxyContin drug produced by the company. The justices determined that the Bankruptcy Code does not authorize the claimant's order, blocking the bankruptcy plan.
