Asphodelin A

Last updated
Asphodelin A
Asphodelin A.svg
Names
IUPAC name
2′,4,4′,7-Tetrahydroxyisoflav-3-en-2-one
Systematic IUPAC name
3-(2,4-Dihydroxyphenyl)-4,7-dihydroxy-2H-1-benzopyran-2-one
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
PubChem CID
  • InChI=1S/C15H10O6/c16-7-1-3-9(11(18)5-7)13-14(19)10-4-2-8(17)6-12(10)21-15(13)20/h1-6,16-19H
    Key: OZOZCKVLUMXFGS-UHFFFAOYSA-N
  • InChI=1/C15H10O6/c16-7-1-3-9(11(18)5-7)13-14(19)10-4-2-8(17)6-12(10)21-15(13)20/h1-6,16-19H
    Key: OZOZCKVLUMXFGS-UHFFFAOYAL
  • C1=CC(=C(C=C1O)O)C2=C(C3=C(C=C(C=C3)O)OC2=O)O
Properties
C15H10O6
Molar mass 286.236
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Asphodelin A is an antimicrobial arylcoumarin made by Asphodelus microcarpus . [1]

Related Research Articles

<span class="mw-page-title-main">Antimicrobial resistance</span> Resistance of microbes to drugs directed against them

Antimicrobial resistance (AMR) occurs when microbes evolve mechanisms that protect them from the effects of antimicrobials. All classes of microbes can evolve resistance where the drugs are no longer effective. Fungi evolve antifungal resistance. Viruses evolve antiviral resistance. Protozoa evolve antiprotozoal resistance, and bacteria evolve antibiotic resistance. Together all of these come under the umbrella of antimicrobial resistance. Microbes resistant to multiple antimicrobials are called multidrug resistant (MDR) and are sometimes referred to as a superbugs. Although antimicrobial resistance is a naturally occurring process, it is often the result of improper usage of the drugs and management of the infections.

<i>Asphodelus ramosus</i> Species of flowering plant

Asphodelus ramosus, the branched asphodel, is a perennial herbaceous plant in the order Asparagales. Similar in appearance to Asphodelus albus and particularly Asphodelus cerasiferus and Asphodelus aestivus, it may be distinguished by its highly branched stem and smaller fruits. There has been a lot of confusion over the nomenclature and taxonomy of the species, owing to its similarity to Asphodelus aestivus.

<i>Asphodelus</i> Genus of flowering plants in the asphodel family Asphodelaceae

Asphodelus is a genus of mainly perennial flowering plants in the asphodel family Asphodelaceae that was first described by Carl Linnaeus in 1753. The genus was formerly included in the lily family (Liliaceae). The genus is native to temperate Europe, the Mediterranean, Africa, the Middle East, and the Indian Subcontinent, and some species have been introduced to, and are now naturalized in, other places such as New Zealand, Australia, Mexico and southwestern United States. Many asphodels are popular garden plants, which grow in well-drained soils with abundant natural light.

<span class="mw-page-title-main">Asphodeloideae</span> Subfamily of flowering plants, in monocot family Asphodelaceae

Asphodeloideae is a subfamily of the monocot family Asphodelaceae in the order Asparagales. It has previously been treated as a separate family, Asphodelaceae sensu stricto. The family Asphodelaceae has now been proposed to be a nomen conservandum, and the proposal has been recommended for ratification in 2017. In that case, Asphodelaceae will have priority over Xanthorrhoeaceae. This is reflected in the APG IV family lists.

An antimicrobial is an agent that kills microorganisms (microbicide) or stops their growth. Antimicrobial medicines can be grouped according to the microorganisms they act primarily against. For example, antibiotics are used against bacteria, and antifungals are used against fungi. They can also be classified according to their function. The use of antimicrobial medicines to treat infection is known as antimicrobial chemotherapy, while the use of antimicrobial medicines to prevent infection is known as antimicrobial prophylaxis.

<i>Asphodelus fistulosus</i> Species of flowering plant

Asphodelus fistulosus is a species of plant known as hollow-stemmed asphodel, onionweed, onion-leafed asphodel, and pink asphodel. It is native to the Mediterranean region. It is an invasive exotic weed in the United States, with significant infestations in California, Arizona, New Mexico, and Texas. It is listed as a Federal Noxious Weed by the United States Department of Agriculture. It is also a common weed in parts of Australia, New Zealand, and Mexico, and it thrives in any area with a Mediterranean climate.

<span class="mw-page-title-main">Antimicrobial peptides</span> Class of peptides that have antimicrobial activity

Antimicrobial peptides (AMPs), also called host defence peptides (HDPs) are part of the innate immune response found among all classes of life. Fundamental differences exist between prokaryotic and eukaryotic cells that may represent targets for antimicrobial peptides. These peptides are potent, broad spectrum antibiotics which demonstrate potential as novel therapeutic agents. Antimicrobial peptides have been demonstrated to kill Gram negative and Gram positive bacteria, enveloped viruses, fungi and even transformed or cancerous cells. Unlike the majority of conventional antibiotics it appears that antimicrobial peptides frequently destabilize biological membranes, can form transmembrane channels, and may also have the ability to enhance immunity by functioning as immunomodulators.

<i>Asphodelus albus</i> Species of plant

Asphodelus albus, common name white asphodel, is a herbaceous perennial plant belonging to the genus Asphodelus.

<i>Lupinus microcarpus</i> Species of legume

Lupinus microcarpus, the wide-bannered lupine or chick lupine, is a species of lupine native to western North America from southwestern British Columbia south through Oregon and California, including the Mojave Desert, and into Baja California. There is also a disjunct population in South America, with locations in central Chile and western Argentina.

Wild onion can refer to

Asphodel can refer to:

<span class="mw-page-title-main">Alonei Yitzhak</span> Place in Haifa, Israel

Alonei Yitzhak is a youth village in northern Israel. Located near Binyamina, it falls under the jurisdiction of Menashe Regional Council. In 2021 it had a population of 305.

<i>Asphodelus tenuifolius</i> Species of flowering plant

Asphodelus tenuifolius is a species of plant in the asphodel family Asphodelaceae. It is native to North Africa, Southern Europe, the Middle East and South Asia. It has been introduced to Australia and the Mascarene Islands. It is generally present from the Canary Islands, across the Mediterranean to the Middle East and Afghanistan. It has a fibrous root system. It is also known as wild onion or "jungli piyaz" in Pakistan.

<i>Mylothris asphodelus</i> Species of butterfly

Mylothris asphodelus is a butterfly in the family Pieridae. It is found in eastern Nigeria, Cameroon, Gabon, the Republic of the Congo, the Democratic Republic of the Congo, Uganda, north-western Tanzania and possibly Angola. The habitat consists of lowland forests. Mylothris asphodelus, like other Mylothris species, occupies the upper portions of forests where the host plants for their larvae are found.

<i>Asphodelus aestivus</i> Species of plant

Asphodelus aestivus, the summer asphodel, is a species of asphodel, a common Western Mediterranean geophyte with a short vertical rhizome and basal leaves. Its flowers are actinomorphic, pinkish-white, with six perianth segments, 14–19 mm long and six stamens of the same length, in two whorls. Its distribution is limited to the Western Mediterranean, mainly found in Portugal and Spain on the European mainland. There has been a lot of confusion over the nomenclature and taxonomy of the species, owing to its similarity to Asphodelus ramosus. It grows in dry grasslands, phrygana and on rocky or sandy ground.

Calothamnus microcarpus is a plant in the myrtle family, Myrtaceae and is endemic to the south-west of Western Australia. It is an erect, either compact or spreading shrub with flat leaves and clusters of red flowers in spring.

Asphodelus bento-rainhae is a species of asphodel, endemic to the Iberian Peninsula.

Asphodelus lusitanicus is a species of asphodel, endemic to the Iberian Peninsula.

<i>Asphodelus acaulis</i> Species of plant

Asphodelus acaulis is a species of asphodel found in North Africa.

Asphodelus viscidulus is a species of asphodel found in North Africa and the Middle East.

References

  1. ↑ El-Seedi, HR (2007). "Antimicrobial arylcoumarins from Asphodelus microcarpus". Journal of Natural Products. 70 (1): 118–20. doi:10.1021/np060444u. PMID   17253862.


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