BOC (gene)

Last updated
BOC
Protein BOC PDB 1x4y.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases BOC , CDON2, BOC cell adhesion associated, oncogene regulated, Boi
External IDs OMIM: 608708; MGI: 2151153; HomoloGene: 32819; GeneCards: BOC; OMA:BOC - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_172506

RefSeq (protein)

NP_766094

Location (UCSC) Chr 3: 113.21 – 113.29 Mb Chr 16: 44.31 – 44.38 Mb
PubMed search [3] [4]
Wikidata
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Brother of CDO is a protein that in humans is encoded by the BOC gene. [5] [6]

CDON (MIM 608707 [ dead link ]) and BOC are cell surface receptors of the immunoglobulin (Ig)/fibronectin type III (FNIII; see MIM 135600 [ dead link ]) repeat family involved in myogenic differentiation. CDON and BOC are coexpressed during development, form complexes with each other in a cis fashion, and are related to each other in their ectodomains, but each has a unique long cytoplasmic tail.[supplied by OMIM] [6]

Interactions

BOC (gene) has been shown to interact with CDON. [5]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000144857 Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000022687 Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. 1 2 Kang JS, Mulieri PJ, Hu Y, Taliana L, Krauss RS (Jan 2002). "BOC, an Ig superfamily member, associates with CDO to positively regulate myogenic differentiation". EMBO J. 21 (1–2): 114–24. doi:10.1093/emboj/21.1.114. PMC   125805 . PMID   11782431.
  6. 1 2 "Entrez Gene: BOC Boc homolog (mouse)".

Further reading