BTBD14B

NACC1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3GA1, 4U2N
Identifiers
Aliases	NACC1 , BEND8, BTBD14B, BTBD30, NAC-1, NAC1, nucleus accumbens associated 1, NECFM
External IDs	OMIM: 610672; MGI: 1914080; HomoloGene: 12042; GeneCards: NACC1; OMA:NACC1 - orthologs
Gene location (Human) Chr. Chromosome 19 (human) [1] Band 19p13.13 Start 13,116,862 bp [1] End 13,141,147 bp [1]
Gene location (Mouse) Chr. Chromosome 8 (mouse) [2] Band 8 C3|8 41.02 cM Start 85,397,108 bp [2] End 85,414,531 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in pancreatic ductal cell nasal epithelium skin of arm stromal cell of endometrium myocardium of left ventricle prefrontal cortex amygdala anterior cingulate cortex buccal mucosa cell decidua Top expressed in tail of embryo genital tubercle epiblast zygote ventricular zone pyloric antrum yolk sac dentate gyrus of hippocampal formation granule cell crypt of lieberkuhn of small intestine superior frontal gyrus More reference expression data BioGPS More reference expression data
Orthologs Species Human Mouse Entrez 112939 66830 Ensembl ENSG00000160877 ENSMUSG00000001910 UniProt Q96RE7 Q7TSZ8 RefSeq (mRNA) NM_052876 NM_025788 RefSeq (protein) NP_443108 NP_080064 Location (UCSC) Chr 19: 13.12 – 13.14 Mb Chr 8: 85.4 – 85.41 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Nucleus accumbens-associated protein 1 is a protein that in humans is encoded by the NACC1 gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000160877 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000001910 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Strausberg RL, Feingold EA, Grouse LH, et al. (Dec 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc Natl Acad Sci U S A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
6. "Entrez Gene: BTBD14B BTB (POZ) domain containing 14B".

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External links

• Human NACC1 genome location and NACC1 gene details page in the UCSC Genome Browser .
• PDBe-KB provides an overview of all the structure information available in the PDB for Human Nucleus accumbens-associated protein 1 (BTBD14B)

Further reading

• Nakayama K, Nakayama N, Wang TL, Shih IeM (2007). "NAC-1 controls cell growth and survival by repressing transcription of Gadd45GIP1, a candidate tumor suppressor". Cancer Res. 67 (17): 8058–64. doi: 10.1158/0008-5472.CAN-07-1357 . PMID   17804717.
• Davidson B, Berner A, Trope' CG, et al. (2007). "Expression and clinical role of the bric-a-brac tramtrack broad complex/poxvirus and zinc protein NAC-1 in ovarian carcinoma effusions". Hum. Pathol. 38 (7): 1030–6. doi:10.1016/j.humpath.2006.12.009. PMID   17391728.
• Nakayama K, Nakayama N, Davidson B, et al. (2007). "A BTB/POZ protein, NAC-1, is related to tumor recurrence and is essential for tumor growth and survival". Proc. Natl. Acad. Sci. U.S.A. 103 (49): 18739–44. doi: 10.1073/pnas.0604083103 . PMC   1693732 . PMID   17130457.
• Korutla L, Wang PJ, Mackler SA (2005). "The POZ/BTB protein NAC1 interacts with two different histone deacetylases in neuronal-like cultures". J. Neurochem. 94 (3): 786–93. doi: 10.1111/j.1471-4159.2005.03206.x . PMID   16033423. S2CID   42787411.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi: 10.1073/pnas.0404720101 . PMC   514446 . PMID   15302935.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Korutla L, Wang PJ, Lewis DM, et al. (2002). "Differences in expression, actions and cocaine regulation of two isoforms for the brain transcriptional regulator NAC1". Neuroscience. 110 (3): 421–9. doi:10.1016/S0306-4522(01)00518-8. PMID   11906783. S2CID   13388723.