Positron emission tomography (PET) is a functional imaging technique that uses radioactive substances known as radiotracers to visualize and measure changes in metabolic processes, and in other physiological activities including blood flow, regional chemical composition, and absorption. Different tracers are used for various imaging purposes, depending on the target process within the body.
[18F]Fluorodeoxyglucose (INN), or fluorodeoxyglucose F 18, also commonly called fluorodeoxyglucose and abbreviated [18F]FDG, 2-[18F]FDG or FDG, is a radiopharmaceutical, specifically a radiotracer, used in the medical imaging modality positron emission tomography (PET). Chemically, it is 2-deoxy-2-[18F]fluoro-D-glucose, a glucose analog, with the positron-emitting radionuclide fluorine-18 substituted for the normal hydroxyl group at the C-2 position in the glucose molecule.
2-Deoxy-d-glucose is a glucose molecule which has the 2-hydroxyl group replaced by hydrogen, so that it cannot undergo further glycolysis. As such; it acts to competitively inhibit the production of glucose-6-phosphate from glucose at the phosphoglucoisomerase level. 2-Deoxyglucose labeled with tritium or carbon-14 has been a popular ligand for laboratory research in animal models, where distribution is assessed by tissue-slicing followed by autoradiography, sometimes in tandem with either conventional or electron microscopy.
Simon N. Powell is a British cancer researcher and radiation oncologist residing in New York City.
H. (Hubert) Rodney Withers was an Australian radiation biologist and physician. He made many contributions to the fields of radiobiology and clinical radiation therapy, but he is best known for his work on post-radiation tissue repair and the effects of ionizing radiation on normal tissues.
Ralph R. Weichselbaum is an American physician specializing in radiation oncology, a member of the Institute of Medicine of the National Academy of Sciences, Ludwig professor, He is Daniel K. Ludwig Distinguished Service Professor of Radiation Oncology and Chairman, Department of Radiation and Cellular Oncology, at the University of Chicago Pritzker School of Medicine, and Head of the University of Chicago Center for Radiation Therapy, and the director of the Chicago Tumor Institute. Weichselbaum is also Co- Director of the Ludwig Center for Metastasis Research at the University of Chicago.
Henry Harrington Janeway was an American physician and pioneer of radiation therapy.
Dr. Kodaganur S. Gopinath, MS, FAMS, FRCS (Edin) is an Indian surgical oncologist, known for his pioneering work on oncological research. He is a recipient of many awards including Dr. B. C. Roy Award, considered to be the premier medical honour in the country. The President of India recognised his services to the field of oncology, by awarding him the fourth highest civilian award, Padma Shri, in 2010.
Prahlada Rama Rao is an Indian missile scientist, former vice chancellor of Defence Institute of Advanced Technology and a former director of Defence Research and Development Laboratory, the largest of the Defence Research and Development Organization laboratories in India, known for his contributions to Indian space programme. He was honoured by the Government of India in 2015 with Padma Shri, the fourth highest Indian civilian award.
Metabolic trapping refers to a localization mechanism of synthesized radiocompounds in the human body. It can be defined as the intracellular accumulation of a radioactive tracer based on the relative metabolic activity of the body's tissues. It is a basic principle of the design of radiopharmaceuticals as metabolic probes for functional studies or tumor location.
Vakkaleri Narayana Rao was an Indian defence scientist and one of the pioneers of Electronic Warfare in India. He was a former director of the Defence Electronics Research Laboratory, Hyderabad. The Government of India awarded him the fourth highest Indian civilian honour of Padma Shri in 1982.
Marco Durante is an Italian physicist, recognized as an expert in the fields of radiobiology and medical physics in charged particle therapy.
Bilikere is a small town in Hunsur taluk of Mysore district in the Indian state of Karnataka.
Sandip Basu is an Indian physician of Nuclear Medicine and the Head, Nuclear Medicine Academic Program at the Radiation Medicine Centre. He is also the Dean-Academic (Health-Sciences), BARC at Homi Bhabha National Institute and is known for his services and research in Nuclear Medicine, particularly on Positron emission tomography diagnostics and Targeted Radionuclide Therapy in Cancer. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards for his contributions to Nuclear Medicine in 2012.
Lorenzo Galluzzi is an Italian and French cell biologist best known for his experimental and conceptual contributions to the fields of cell death, autophagy, tumor metabolism and tumor immunology.
Dr. Daniel Przybysz is a Brazilian Radiation-Oncologist. His practice is mainly focused on lung cancer treatment and high technology approaches toward better patient care
Bangalore Srinivasarao Madhava Rao was an Indian mathematician and physicist who served as a professor of mathematics at Central College, Bangalore. He worked on mathematical physics and collaborated with Max Born.
Sanjeev Das is an Indian cancer biologist and a scientist at National Institute of Immunology, New Delhi, India. He is well regarded for his studies on tumor suppressor proteins. He is a recipient of the National Bioscience Award for Career Development of the Department of Biotechnology. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, for his contributions to biological sciences in 2017.
Kristy Brock is a professor in the Department of Imaging Physics, Division of Diagnostic Imaging and is an adjunct professor in the Department of Radiation Physics, Division of Radiation Oncology at the University of Texas MD Anderson Cancer Center, Houston.
Vasudeva Kilara Iya is an Indian nuclear scientist and the First Head of the radioisotope and radiation technology programme of the Department of Atomic Energy (DAE) and a former Group Director at BARC (1974–1987).
