Names | |
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IUPAC name 1-((3S,4S)-5-Hydroxy-4-methyloxolan-3-yl)ethanone | |
Other names (-)-Botryodiplodin | |
Identifiers | |
3D model (JSmol) | |
ChEBI | |
ChEMBL | |
ChemSpider | |
PubChem CID | |
UNII | |
CompTox Dashboard (EPA) | |
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Properties | |
C7H12O3 | |
Molar mass | 144.170 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). |
Botryodiplodin is an antibiotic mycotoxin produced by Penicillium . [1]
Mold health issues refer to the harmful health effects of molds and their mycotoxins. Approximately 47% of houses in the United States have substantial levels of mold, with over 85% of commercial and office buildings found to have water damage predictive of mold. As many as 21% of asthma cases may result from exposure to mold. Substantial and statistically significant increases in the risks of both respiratory infections and bronchitis have been associated with dampness in homes and the resulting mold.
A mold or mould is one of the structures that certain fungi can form. The dust-like, colored appearance of molds is due to the formation of spores containing fungal secondary metabolites. The spores are the dispersal units of the fungi. Not all fungi form molds. Some fungi form mushrooms; others grow as single cells and are called microfungi.
Penicillium is a genus of ascomycetous fungi that is part of the mycobiome of many species and is of major importance in the natural environment, in food spoilage, and in food and drug production.
A mycotoxin is a toxic secondary metabolite produced by fungi and is capable of causing disease and death in both humans and other animals. The term 'mycotoxin' is usually reserved for the toxic chemical products produced by fungi that readily colonize crops.
Blue cheese is any of a wide range of cheeses made with the addition of cultures of edible molds, which create blue-green spots or veins through the cheese. Blue cheeses vary in taste from very mild to strong, and from slightly sweet to salty or sharp; in colour from pale to dark; and in consistency from liquid to hard. They may have a distinctive smell, either from the mold or from various specially cultivated bacteria such as Brevibacterium linens.
Umqombothi, is a South African traditional beer made from maize (corn), maize malt, sorghum malt, yeast and water. It is very rich in vitamin B. The beer has a rather low alcohol content and is known to have a heavy and distinctly sour aroma. In appearance, the beer is opaque and light tan. It has a thick, creamy, and gritty consistency.
Penicillium roqueforti is a common saprotrophic fungus in the genus Penicillium. Widespread in nature, it can be isolated from soil, decaying organic matter, and plants.
Penicillium camemberti is a species of fungus in the genus Penicillium. It is used in the production of Camembert, Brie, Langres, Coulommiers, and Cambozola cheeses, on which colonies of P. camemberti form a hard, white crust. It is responsible for giving these cheeses their distinctive flavors. An allergy to the antibiotic penicillin does not necessarily imply an allergy to cheeses made using P. camemberti.
Ochratoxins are a group of mycotoxins produced by some Aspergillus species and some Penicillium species, especially P. verrucosum. Ochratoxin A is the most prevalent and relevant fungal toxin of this group, while ochratoxins B and C are of lesser importance.
Mycotoxicology is the branch of mycology that focuses on analyzing and studying the toxins produced by fungi, known as mycotoxins. In the food industry it is important to adopt measures that keep mycotoxin levels as low as practicable, especially those that are heat-stable. These chemical compounds are the result of secondary metabolism initiated in response to specific developmental or environmental signals. This includes biological stress from the environment, such as lower nutrients or competition for those available. Under this secondary path the fungus produces a wide array of compounds in order to gain some level of advantage, such as incrementing the efficiency of metabolic processes to gain more energy from less food, or attacking other microorganisms and being able to use their remains as a food source.
Roquefortine C is a mycotoxin that belongs to a class of naturally occurring 2,5-diketopiperazines produced by various fungi, particularly species from the genus Penicillium. It was first isolated from a strain of Penicillium roqueforti, a species commercially used as a source of proteolytic and lipolytic enzymes during maturation of the blue-veined cheeses, Roquefort, Danish Blue, Stilton and Gorgonzola.
Cyclochlorotine (CC), also known as islanditoxin, is a mycotoxin produced by the fungus Penicillium islandicum that causes liver damage and has carcinogenic properties. Japanese researchers confirmed that it was one of three strains of Penicillin fungi responsible for yellowed rice. It is listed as an IARC Group 3 carcinogen.
Verrucosidin is a toxic pyrone-type polyketide produced by Penicillium aurantiogriseum, Penicillium melanoconidium, and Penicillium polonicum.
Penicillium brunneum is an anamorph fungus species of the genus of Penicillium which was isolated in imported rice an produces rugulosin a substance which is hepatocarcinogenic to mice and rats.
Penicillium corynephorum is an anamorph species of the genus of Penicillium.
Yellowed rice refers to three kinds of rice grains contaminated with different strains of Penicillium fungi—Yellow rice, Citrinum yellow rice, and Islandia yellow rice. These rice grains were first identified in Japan in 1964, after the research was interrupted by World War II. The first of the yellowed rice strains has been linked to shoshin-kakke. Citrinum yellow rice and Islandia yellow rice are not known to have caused any adverse effects in human populations.
Penicillium marinum is a species in the genus Penicillium which produces patulin and roquefortine C.
Penicillium viridicatum is a psychrophilic species of fungus in the genus, penicillic acid and citrinin. Penicillium viridicatum can spoil grapes and melons.
Penicillium verrucosum is a psychrophilic fungus which was discovered in Belgium and introduced by Dierckx in 1901. Six varieties of this species have been recognized based primarily on differences in colony colour: P. verrucosum var. album, P. verrucosum var. corymbiferum, P. verrucosum var. cyclopium, P. verrucosum var. ochraceum, P. verrucosum var. melanochlorum and P. verrucosum var. verrucosum. This fungus has important implications in food, specifically for grains and other cereal crops on which it grows. Its growth is carefully regulated in order to reduce food spoilage by this fungi and its toxic products. The genome of P. verrucosum has been sequenced and the gene clusters for the biosyntheses of its mycotoxins have been identified.
Citreoviridin is a mycotoxin which is produced by Penicillium and Aspergillus species. If rice, corn, cereals or meat products are contaminated with Penicillin citreoviridin, citreoviridin can be produced if the food is stored in a damp place. Consuming food which is contaminated with citreoviridin can cause the disease cardiac beri beri. Furthermore, it damages liver and kidneys.